Implementation of FoldMark: Safeguarding Protein Structure Generative Models with Distributional and Evolutionary Watermarking
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Updated
Apr 19, 2026 - Python
Implementation of FoldMark: Safeguarding Protein Structure Generative Models with Distributional and Evolutionary Watermarking
Safety concept for Global Health Engineering
Safety-facing carve-out: PBS-stratified abstention/calibration on 5 biology domains (CT/ADMET/SC-Perturbation/ClinVar/GWAS) × 2 providers × 2 prompt conditions
Mapping the distribution of high-containment laboratories and projected climate-related hazards
Public-safe synthetic agentic bio-safeguard eval. 26 cases / 52 fixtures / 9 deterministic hard gates / Replay Ledger export. Not a capability benchmark.
LabCraft-Eval: a stochastic Inspect AI environment for evaluating AI agents on benign molecular-microbiology protocols, with deterministic four-axis trajectory scoring.
Biological dual-use content classifier using Constitutional Classifiers methodology — biosafety constitution, synthetic data pipeline, DeBERTa-v3-base classifier
Public runtime library for microorganism risk-reference data derived from NITE/MRINDA.
30 machine-readable constitutional rules for biological dual-use content across 6 bio domains. JSON format for Constitutional Classifier pipeline integration.
Empirical dual-use risk assessment of protein language models (ESM-2) and structure-based design tools (ProteinMPNN)
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