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Contributor submission PumG #210

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Merged
mmzdouc merged 6 commits into from
Feb 27, 2026
Merged

Contributor submission PumG #210

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8cd5bd4
Add submission UUID file
mite-bot Feb 27, 2026
92568a0
Update entry MITE0000100
mite-bot Feb 27, 2026
45f55a7
Update submission
mite-bot Feb 27, 2026
236435e
Update submission
mite-bot Feb 27, 2026
913e685
Delete mite_data/data/0dbbc78e-13c1-11f1-8244-9f391af45cf2.json
mite-bot Feb 27, 2026
5fbc9c3
Update submission
mite-bot Feb 27, 2026
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21 changes: 17 additions & 4 deletions mite_data/data/MITE0000100.json
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Original file line number Diff line number Diff line change
Expand Up @@ -26,6 +26,17 @@
"0000-0001-6534-6609"
],
"comment": "Replaced retired UniProtKB ID with UniParc ID"
},
{
"version": "3",
"date": "2026-02-27",
"contributors": [
"AAAAAAAAAAAAAAAAAAAAAAAA"
],
"reviewers": [
"0000-0001-6534-6609"
],
"comment": "Added reaction description, removed MIBiG accession BGC0001476 (does not exist in MIBiG 4.0)."
}
],
"enzyme": {
Expand All @@ -36,28 +47,30 @@
],
"databaseIds": {
"uniprot": "UPI000D218CF8",
"genpept": "AVT42376.1",
"mibig": "BGC0001476"
"genpept": "AVT42376.1"
}
},
"reactions": [
{
"tailoring": [
"Amination"
],
"description": "Performs amination of 5'-oxo-pseudouridine in the pseudouridimycin pathway.",
"reactionSMARTS": "[#8:1]\\[#6@:2]1-[#6@@:6](\\[#8:7])-[#6@:5](/[#6:8]2:[#6:14](=[#8:15]):[nH:13]:[#6:11](=[#8:12]):[nH:10]:[#6:9]:2)-[#8:4]-[#6@@:3]-1/[#6:16]=[#8]>>[#7]-[#6:16]/[#6@@:3]1-[#6@@:2](\\[#8:1])-[#6@@:6](\\[#8:7])-[#6@:5](/[#6:8]2:[#6:14](=[#8:15]):[nH:13]:[#6:11](=[#8:12]):[nH:10]:[#6:9]:2)-[#8:4]-1",
"reactions": [
{
"substrate": "O=C[C@H]1O[C@@H](c2c[nH]c(=O)[nH]c2=O)[C@H](O)[C@@H]1O",
"products": [
"NC[C@H]1O[C@@H](c2c[nH]c(=O)[nH]c2=O)[C@H](O)[C@@H]1O"
],
"isIntermediate": false
"isIntermediate": true,
"description": "Converts 5'-oxo-pseudouridine to 5'-aminopseudouridine"
}
],
"evidence": {
"evidenceCode": [
"Knock-out studies"
"Knock-out studies",
"Site-directed mutagenesis"
],
"references": [
"doi:10.1016/j.chembiol.2018.02.008"
Expand Down