π Columbus, OH | 𧬠Biomedical AI Infrastructure
Building AI agent infrastructure for biomedical research β bridging LLMs, cloud computing, and multi-omics data at Ohio State's Comprehensive Cancer Center.
- A platform for the biomedical application of large language models β Nature Biotechnology 2025 doi
- Common and divergent cellular aetiologies underlying HLHS and HRHS β European Heart Journal 2025 doi
- Cell-free RNA signatures in maternal blood with fetal congenital heart disease β Circulation Research 2024 doi
- Identifying intratumoral microbes from the ORIEN dataset β Cancer Research Communications 2024 doi β
- Abnormal progenitor cell differentiation in hypoplastic right heart syndrome β Circulation 2024 doi
- Impaired human cardiac cell development due to NOTCH1 deficiency β Circulation Research 2023 doi β
- Microglia coordinate cellular interactions during spinal cord repair β Nature Communications 2022 doi
- NIH SenNet Consortium to map senescent cells throughout the human lifespan β Nature Aging 2022 doi
- ssREAD: A single-cell and spatial RNA-seq database for Alzheimer's disease β Nature Communications 2024 doi β
- scGNN: A novel graph neural network framework for single-cell RNA-Seq β Nature Communications 2021 doi
- IRIS3: Integrated cell-type-specific regulon inference server from scRNA-Seq β Nucleic Acids Research 2020 doi β
- scREAD: A single-cell RNA-Seq database for Alzheimer's disease β iScience 2020 doi β
β first or co-first author
- AI Agent Systems - RAG pipelines, knowledge graphs, LLM integration for biomedical research workflows
- Cloud Infrastructure - Designing and managing HIPAA-compliant research computing platforms (AWS, Azure)
- Multi-omics Analysis - Single-cell, spatial transcriptomics, and multi-omics data for cancer immunotherapy and neurodegenerative diseases
- Full-stack Development - Research web applications, databases, and knowledgebases (Vue.js, NestJS, TypeScript, MySQL)
Background
- MS Plant Science, South Dakota State University
- BS Software Engineering, Beijing Jiaotong University
- 7+ years building bioinformatics tools and cloud infrastructure at OSU
- Pelotonia Institute for Immuno-Oncology, Ohio State Comprehensive Cancer Center





