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IMAT

IMO Methods & Tools Lecture Series

Goal

The purpose of this series is to offer additional training in common methods used in IMO. Topics will be chosen based on student feedback, and we aim to build a resource & library of lecture materials, examples, and code to be used year-on-year.

List of lectures

1. Visualization, analysis and design

Summary: A review of the construction of scientific figures and illustrations, including topics like data encoding using size, shape, color. We review the physical limits of human perception, the history of illustration methods, and make recommendations on best practices. Presented by Jeffrey West.

2. Integrating HAL with EvoFreq

Summary: An overview of lineage tracing, with a tutorial of Hybrid Automata Library (HAL) and its integration with EvoFreq, a tool for visualizing lineage information. Presented by Chandler Gatenbee & Sadegh Marzban.

3. Cancer Medicine and Action Mechanisms of Drugs

Summary: an overview of common drugs used in cancer, along with description of mechanism of action. Presented by Vural Tagal.

4. Bayesian inference: a theory of parameter estimation

Summary: An overview of the fundamental theory of Bayesian inference underlying parameter estimation using the exponential tumor growth law as a motivating example. Maximum a posteriori (MAP) estimation is motivated and demonstrated. Sampling methods are motivated for future exploration. Presented by Daniel Glazar.

5. Virtual Patient Cohorts

Summary: An overview of the motivation and process for generating virtual patient cohorts, with included explanation and examples from the Evolutionary Tumor Board at Moffitt Cancer Center. Presented by Mark Robertson-Tessi.

6. Clustering & visualization of high-dimensional data

Summary: An overview of the motivation and process for visualization of high-dimensional data using techniques like UMAP, t-SNE, and PCA. Presented by Sandhya Prabhakaran.

7. Science Communication

Summary: "How I learned to start worrying and love SciComm" -- an overview of strategies for science communication, presented by Parmvir Bahia.

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