diff --git a/CHANGELOG.md b/CHANGELOG.md
index 41155363..6045196c 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -1,5 +1,9 @@
 ## [Unreleased]
 
+### Added
+
+- Implement `FiberScheduler#fiber_interrupt` (#283).
+
 ## [1.24.0] - 2026-05-12
 
 ### Added
diff --git a/lib/rage/fiber.rb b/lib/rage/fiber.rb
index eb9ed97d..a7e02d08 100644
--- a/lib/rage/fiber.rb
+++ b/lib/rage/fiber.rb
@@ -111,23 +111,7 @@ def __get_id
   end
 
   # @private
-  def __block_channel(force = false)
-    @__block_channel_i ||= 0
-    @__block_channel_i += 1 if force
-
-    "block:#{object_id}:#{@__block_channel_i}"
-  end
-
-  # @private
-  def __await_channel(force = false)
-    @__fiber_channel_i ||= 0
-    @__fiber_channel_i += 1 if force
-
-    "await:#{object_id}:#{@__fiber_channel_i}"
-  end
-
-  # @private
-  attr_accessor :__awaited_fileno
+  attr_accessor :__awaited_fileno, :__wait_generation, :__block_channel, :__await_channel
 
   # @private
   # pause a fiber and resume in the next iteration of the event loop
@@ -156,7 +140,10 @@ class << self
   # @note This method should only be used when multiple fibers have to be processed in parallel. There's no need to use `Fiber.await` for single IO calls.
   def self.await(fibers)
     f, fibers = Fiber.current, Array(fibers)
-    await_channel = f.__await_channel(true)
+
+    f.__wait_generation ||= 0
+    gen = (f.__wait_generation += 1)
+    channel = f.__await_channel = "await:#{f.object_id}:#{gen}"
 
     Rage::Telemetry.tracer.span_core_fiber_await(fibers:) do
       # check which fibers are alive (i.e. have yielded) and which have errored out
@@ -179,17 +166,21 @@ def self.await(fibers)
       end
 
       # wait on async fibers; resume right away if one of the fibers errors out
-      Iodine.subscribe(await_channel) do |_, err|
-        if err == AWAIT_ERROR_MESSAGE
-          f.resume
+      Iodine.subscribe(channel) do |_, err|
+        done = if err == AWAIT_ERROR_MESSAGE
+          true
         else
           num_wait_for -= 1
-          f.resume if num_wait_for == 0
+          num_wait_for == 0
+        end
+
+        if done
+          Iodine.defer { Iodine.unsubscribe(channel) }
+          f.resume if f.alive? && gen == f.__wait_generation
         end
       end
 
       Fiber.defer(-1)
-      Iodine.defer { Iodine.unsubscribe(await_channel) }
 
       # if num_wait_for is not 0 means we exited prematurely because of an error
       if num_wait_for > 0
diff --git a/lib/rage/fiber_scheduler.rb b/lib/rage/fiber_scheduler.rb
index 5bec50c0..65e0a48e 100644
--- a/lib/rage/fiber_scheduler.rb
+++ b/lib/rage/fiber_scheduler.rb
@@ -12,7 +12,11 @@ def initialize
 
   def io_wait(io, events, timeout = nil)
     f = Fiber.current
-    ::Iodine::Scheduler.attach(io.fileno, events, timeout&.ceil) { |err| f.resume(err) }
+    gen = (f.__wait_generation += 1)
+
+    ::Iodine::Scheduler.attach(io.fileno, events, timeout&.ceil) do |err|
+      f.resume(err) if f.alive? && gen == f.__wait_generation
+    end
 
     err = Fiber.defer(io.fileno)
     if err == false || (err && err < 0)
@@ -91,13 +95,16 @@ def address_resolve(hostname)
   end
 
   def block(_blocker, timeout = nil)
-    f, fulfilled, channel = Fiber.current, false, Fiber.current.__block_channel(true)
+    f, fulfilled = Fiber.current, false
+
+    gen = (f.__wait_generation += 1)
+    channel = f.__block_channel = "block:#{f.object_id}:#{gen}"
 
     resume_fiber_block = proc do
       unless fulfilled
         fulfilled = true
         ::Iodine.defer { ::Iodine.unsubscribe(channel) }
-        f.resume if f.alive?
+        f.resume if f.alive? && gen == f.__wait_generation
       end
     end
 
@@ -110,7 +117,12 @@ def block(_blocker, timeout = nil)
   end
 
   def unblock(_blocker, fiber)
-    ::Iodine.publish(fiber.__block_channel, "", Iodine::PubSub::PROCESS)
+    ::Iodine.publish(fiber.__block_channel, "", Iodine::PubSub::PROCESS) if fiber.__block_channel
+  end
+
+  def fiber_interrupt(fiber, exception)
+    fiber.__wait_generation += 1
+    fiber.raise(exception)
   end
 
   def fiber(&block)
@@ -131,13 +143,14 @@ def fiber(&block)
           Fiber.current.__set_result(block.call)
         end
         # send a message for `Fiber.await` to work
-        Iodine.publish(parent.__await_channel, "", Iodine::PubSub::PROCESS) if parent.alive?
+        Iodine.publish(parent.__await_channel, "", Iodine::PubSub::PROCESS) if parent.__await_channel
       rescue Exception => e
         Fiber.current.__set_err(e)
-        Iodine.publish(parent.__await_channel, Fiber::AWAIT_ERROR_MESSAGE, Iodine::PubSub::PROCESS) if parent.alive?
+        Iodine.publish(parent.__await_channel, Fiber::AWAIT_ERROR_MESSAGE, Iodine::PubSub::PROCESS) if parent.__await_channel
       end
     end
 
+    fiber.__wait_generation = 0
     fiber.resume
 
     fiber
diff --git a/spec/fiber_scheduler_spec.rb b/spec/fiber_scheduler_spec.rb
index f5f49ba9..3f8bdc91 100644
--- a/spec/fiber_scheduler_spec.rb
+++ b/spec/fiber_scheduler_spec.rb
@@ -356,4 +356,163 @@
       -> { raise e }
     end
   end
+
+  context "fiber interruption" do
+    before do
+      skip("skipping on Ruby < 4") if Gem::Version.create(RUBY_VERSION) < Gem::Version.create(4)
+    end
+
+    it "correctly interrupts a fiber" do
+      within_reactor do
+        error = begin
+          r, _ = IO.pipe
+
+          child = Fiber.schedule do
+            r.gets
+          end
+
+          Fiber.schedule do
+            r.close # This will interrupt the child fiber.
+          end
+
+          Fiber.await(child)
+        rescue => e
+          e
+        end
+
+        -> { expect(error).to be_a(IOError) }
+      end
+    end
+  end
+
+  context "with wait generation tracking" do
+    it "initializes __wait_generation to 0 for scheduled fibers" do
+      within_reactor do
+        fiber = Fiber.schedule { Fiber.current.__wait_generation }
+        result = Fiber.await(fiber)
+
+        -> { expect(result).to eq([0]) }
+      end
+    end
+
+    it "increments __wait_generation on each block call" do
+      queue1 = Queue.new
+      queue2 = Queue.new
+
+      Thread.new do
+        sleep 0.2
+        queue1 << "first"
+        sleep 0.2
+        queue2 << "second"
+      end
+
+      within_reactor do
+        gen_before = Fiber.current.__wait_generation
+        queue1.pop
+        gen_after_first = Fiber.current.__wait_generation
+        queue2.pop
+        gen_after_second = Fiber.current.__wait_generation
+
+        -> do
+          expect(gen_after_first).to eq(gen_before + 1)
+          expect(gen_after_second).to eq(gen_before + 2)
+        end
+      end
+    end
+
+    it "increments __wait_generation on Fiber.await" do
+      within_reactor do
+        gen_before = Fiber.current.__wait_generation
+
+        Fiber.await(Fiber.schedule { sleep 0.1 })
+        gen_after_first = Fiber.current.__wait_generation
+
+        Fiber.await(Fiber.schedule { sleep 0.1 })
+        gen_after_second = Fiber.current.__wait_generation
+
+        -> do
+          expect(gen_after_first).to eq(gen_before + 1)
+          expect(gen_after_second).to eq(gen_before + 2)
+        end
+      end
+    end
+
+    it "prevents stale resume when fiber moves to new wait state" do
+      queue1 = Queue.new
+      queue2 = Queue.new
+      old_channel = nil
+      results = []
+
+      within_reactor do
+        fiber = Fiber.schedule do
+          f = Fiber.current
+
+          # Start a thread that will:
+          # 1. Unblock the first wait
+          # 2. Capture the old channel
+          # 3. Try to publish to the old channel while fiber is in second wait
+          Thread.new do
+            sleep 0.1
+            old_channel = f.__block_channel
+            queue1 << "first"
+
+            sleep 0.2
+            # Try to publish to the old channel (simulating a stale unblock)
+            # This shouldn't resume the fiber because generation has changed
+            Iodine.publish(old_channel, "", Iodine::PubSub::PROCESS)
+          end
+
+          results << queue1.pop
+          results << "starting second wait"
+
+          # Start second unblock thread
+          Thread.new { sleep 0.5; queue2 << "second" }
+
+          # Now block on second queue - stale resume from old_channel should be ignored
+          results << queue2.pop
+          results
+        end
+
+        result = Fiber.await(fiber)
+        -> { expect(result.first).to eq(["first", "starting second wait", "second"]) }
+      end
+    end
+
+    it "fiber_interrupt increments generation before raising" do
+      test_fiber = nil
+      generation_before = nil
+      generation_in_rescue = nil
+
+      within_reactor do
+        test_fiber = Fiber.schedule do
+          generation_before = Fiber.current.__wait_generation
+
+          begin
+            sleep 10 # Block for a long time
+          rescue => e
+            generation_in_rescue = Fiber.current.__wait_generation
+            raise e
+          end
+        end
+
+        # Give the fiber time to start sleeping
+        sleep 0.1
+
+        # Interrupt the fiber
+        Fiber.scheduler.fiber_interrupt(test_fiber, RuntimeError.new("interrupted"))
+
+        # Wait for fiber to process the exception
+        sleep 0.1
+
+        -> do
+          # generation_before is 0 (after init)
+          # sleep increments to 1
+          # fiber_interrupt increments to 2
+          expect(generation_in_rescue).to eq(generation_before + 2)
+          expect(test_fiber.__get_err).to be_a(RuntimeError)
+          expect(test_fiber.__get_err.message).to eq("interrupted")
+        end
+      end
+    end
+  end
 end
diff --git a/spec/fiber_spec.rb b/spec/fiber_spec.rb
index a1954984..3116cd9b 100644
--- a/spec/fiber_spec.rb
+++ b/spec/fiber_spec.rb
@@ -193,4 +193,75 @@
       -> {}
     end
   end
+
+  it "correctly processes killed fibers" do
+    within_reactor do
+      f = Fiber.schedule { sleep 30 }
+
+      Fiber.schedule do
+        sleep 1
+        f.kill
+      end
+
+      result = Fiber.await(f)
+
+      -> { expect(result).to eq([nil]) }
+    end
+  end
+
+  it "correctly processes killed fibers" do
+    within_reactor do
+      f1 = Fiber.schedule { sleep 30 }
+
+      f2 = Fiber.schedule do
+        sleep 0.5
+        "test result"
+      end
+
+      Fiber.schedule do
+        sleep 1
+        f1.kill
+      end
+
+      result = Fiber.await([f1, f2])
+
+      -> { expect(result).to eq([nil, "test result"]) }
+    end
+  end
+
+  context "with wait generation tracking" do
+    it "uses unique await channels for each Fiber.await call" do
+      within_reactor do
+        channels = []
+
+        Fiber.await(Fiber.schedule { sleep 0.05 })
+        channels << Fiber.current.__await_channel
+
+        Fiber.await(Fiber.schedule { sleep 0.05 })
+        channels << Fiber.current.__await_channel
+
+        Fiber.await(Fiber.schedule { sleep 0.05 })
+        channels << Fiber.current.__await_channel
+
+        -> { expect(channels.uniq.size).to eq(3) }
+      end
+    end
+
+    it "increments __wait_generation for each await" do
+      within_reactor do
+        generations = [Fiber.current.__wait_generation]
+
+        Fiber.await(Fiber.schedule { sleep 0.05 })
+        generations << Fiber.current.__wait_generation
+
+        Fiber.await(Fiber.schedule { sleep 0.05 })
+        generations << Fiber.current.__wait_generation
+
+        -> do
+          expect(generations[1]).to eq(generations[0] + 1)
+          expect(generations[2]).to eq(generations[0] + 2)
+        end
+      end
+    end
+  end
 end