diff --git a/.github/docker-image-mirror-config.yaml b/.github/docker-image-mirror-config.yaml
new file mode 100644
index 0000000000..e4d5746a9f
--- /dev/null
+++ b/.github/docker-image-mirror-config.yaml
@@ -0,0 +1,27 @@
+# Mirror configuration with SHA256 digests for immutability
+# Format: source → destination with SHA digest
+
+images:
+  # Flyway images (Docker Hub)
+  - source: flyway/flyway:10-alpine
+    destination: ghcr.io/loculus-project/flyway:10-alpine
+    digest: "sha256:f736d2d71e8a120d3950a67c1b4cdf155cf3a6d8be149b4ec784f24dbf22f50f"
+  
+  - source: flyway/flyway:11.10.0-alpine-mongo
+    destination: ghcr.io/loculus-project/flyway:11.10.0-alpine-mongo
+    digest: "sha256:1398d6a9223ae0f2164d15282c029614d60df826c500f6b78d86498422837945"
+  
+  # MinIO (Quay.io)
+  - source: quay.io/minio/minio:latest
+    destination: ghcr.io/loculus-project/minio:latest
+    digest: "sha256:9966a92a734f9411e32f4f41d7d9d826fcdc0f68c4e20b70295bd4e7c11f8a2f"
+  
+  # Keycloak (Quay.io)
+  - source: quay.io/keycloak/keycloak:23.0
+    destination: ghcr.io/loculus-project/keycloak:23.0
+    digest: "sha256:461bdabba2bd2de667b19b0c1831754cb0f1c6c1d1c85cd35ccfa65335078962"
+  
+  # Busybox (K8s registry)
+  - source: registry.k8s.io/busybox:latest
+    destination: ghcr.io/loculus-project/busybox:latest
+    digest: "sha256:d8d3bc2c183ed2f9f10e7258f84971202325ee6011ba137112e01e30f206de67"
diff --git a/.github/workflows/ena-submission-workflow-tests.yml b/.github/workflows/ena-submission-workflow-tests.yml
index f039ae5717..e9558c11b0 100644
--- a/.github/workflows/ena-submission-workflow-tests.yml
+++ b/.github/workflows/ena-submission-workflow-tests.yml
@@ -17,7 +17,7 @@ jobs:
       ENA_PASSWORD: ${{ secrets.ENA_SUBMISSION_PASSWORD }}
     services:
       postgres:
-        image: postgres:15
+        image: ghcr.io/cloudnative-pg/postgresql@sha256:8e08e8d876545a0ce1cd5aa3c13923181f1d51d419cb618bc52832f4c89fda06
         env:
           POSTGRES_USER: postgres
           POSTGRES_PASSWORD: unsecure
diff --git a/.github/workflows/mirror-docker-images.yml b/.github/workflows/mirror-docker-images.yml
new file mode 100644
index 0000000000..64f9f67979
--- /dev/null
+++ b/.github/workflows/mirror-docker-images.yml
@@ -0,0 +1,79 @@
+name: Mirror Images to GHCR
+
+on:
+  schedule:
+    - cron: '0 3 * * *'  # Daily at 3 AM UTC
+  workflow_dispatch:
+    inputs:
+      force_mirror:
+        description: 'Force mirror all images'
+        type: boolean
+        default: false
+
+permissions:
+  packages: write
+  contents: write  # Need write to update config with digests
+
+jobs:
+  mirror:
+    runs-on: ubuntu-latest
+    steps:
+      - uses: actions/checkout@v6
+
+      - name: Log in to GHCR
+        uses: docker/login-action@v3
+        with:
+          registry: ghcr.io
+          username: ${{ github.actor }}
+          password: ${{ secrets.GITHUB_TOKEN }}
+
+      - name: Log in to Docker Hub (if secrets available)
+        if: ${{ secrets.DOCKERHUB_USERNAME != '' }}
+        uses: docker/login-action@v3
+        with:
+          username: ${{ secrets.DOCKERHUB_USERNAME }}
+          password: ${{ secrets.DOCKERHUB_TOKEN_READ_PUBLIC }}
+
+      - name: Mirror images and update digests
+        env:
+          FORCE: ${{ inputs.force_mirror || 'false' }}
+        run: |
+          set -euo pipefail
+          
+          images=$(yq eval '.images | length' .github/docker-image-mirror-config.yaml)
+          updated=false
+          
+          for i in $(seq 0 $((images - 1))); do
+            source=$(yq eval ".images[$i].source" .github/docker-image-mirror-config.yaml)
+            dest=$(yq eval ".images[$i].destination" .github/docker-image-mirror-config.yaml)
+            current_digest=$(yq eval ".images[$i].digest" .github/docker-image-mirror-config.yaml)
+            
+            # Get source digest
+            source_digest=$(docker manifest inspect "$source" 2>/dev/null | jq -r 'if .manifests then .manifests[0].digest else .config.digest // "unknown" end')
+            
+            # Skip if digest matches and not forced
+            if [ "$FORCE" != "true" ] && [ "$current_digest" = "$source_digest" ]; then
+              echo "$source: skipping (unchanged)"
+              continue
+            fi
+            
+            echo "$source → $dest"
+            docker pull "$source" >/dev/null 2>&1
+            docker tag "$source" "$dest"
+            docker push "$dest" >/dev/null 2>&1
+            
+            # Update digest in config
+            yq eval ".images[$i].digest = \"$source_digest\"" -i .github/docker-image-mirror-config.yaml
+            updated=true
+          done
+          
+          echo "updated=$updated" >> $GITHUB_ENV
+
+      - name: Commit digest updates
+        if: env.updated == 'true'
+        run: |
+          git config user.name "github-actions[bot]"
+          git config user.email "github-actions[bot]@users.noreply.github.com"
+          git add .github/docker-image-mirror-config.yaml
+          git commit -m "chore: Update image digests after mirroring"
+          git push
diff --git a/.github/workflows/schema-dump.yml b/.github/workflows/schema-dump.yml
index a49e61fbbb..653c32c05e 100644
--- a/.github/workflows/schema-dump.yml
+++ b/.github/workflows/schema-dump.yml
@@ -19,7 +19,7 @@ jobs:
 
     services:
       postgres:
-        image: postgres:15
+        image: ghcr.io/cloudnative-pg/postgresql@sha256:8e08e8d876545a0ce1cd5aa3c13923181f1d51d419cb618bc52832f4c89fda06
         env:
           POSTGRES_PASSWORD: postgres
           POSTGRES_DB: postgres
@@ -40,7 +40,7 @@ jobs:
         fetch-depth: 0
 
     - name: Run Flyway migrations
-      uses: docker://flyway/flyway:10-alpine
+      uses: docker://ghcr.io/loculus-project/flyway@sha256:f736d2d71e8a120d3950a67c1b4cdf155cf3a6d8be149b4ec784f24dbf22f50f
       env:
         FLYWAY_URL: jdbc:postgresql://postgres:5432/postgres
         FLYWAY_USER: postgres
@@ -49,7 +49,7 @@ jobs:
         args: -locations=filesystem:./backend/src/main/resources/db/migration/ migrate
 
     - name: Generate new schema
-      uses: docker://postgres:16
+      uses: docker://ghcr.io/cloudnative-pg/postgresql@sha256:8e08e8d876545a0ce1cd5aa3c13923181f1d51d419cb618bc52832f4c89fda06
       with:
         args: >
           bash -c "PGPASSWORD=postgres pg_dump 
diff --git a/ena-submission/flyway/Dockerfile b/ena-submission/flyway/Dockerfile
index a0ab7a695b..613b998cf7 100644
--- a/ena-submission/flyway/Dockerfile
+++ b/ena-submission/flyway/Dockerfile
@@ -1,6 +1,6 @@
 # The version number is also used in the ena-submission-workflow-tests.yml file to extract the Flyway version dynamically.
 # We thus require a specific major.minor.patch version here
-FROM flyway/flyway:11.10.0-alpine-mongo
+FROM ghcr.io/loculus-project/flyway@sha256:1398d6a9223ae0f2164d15282c029614d60df826c500f6b78d86498422837945
 
 # Copy configuration and SQL files
 COPY conf /flyway/conf
diff --git a/kubernetes/loculus/templates/ingest-deployment.yaml b/kubernetes/loculus/templates/ingest-deployment.yaml
index 4beb7cb35d..99d75d3f95 100644
--- a/kubernetes/loculus/templates/ingest-deployment.yaml
+++ b/kubernetes/loculus/templates/ingest-deployment.yaml
@@ -28,7 +28,7 @@ spec:
       {{- include "possiblePriorityClassName" $ | nindent 6 }}
       initContainers:
         - name: version-check
-          image: busybox
+          image: ghcr.io/loculus-project/busybox@sha256:d8d3bc2c183ed2f9f10e7258f84971202325ee6011ba137112e01e30f206de67
           {{- include "loculus.resources" (list "ingest-init" $.Values) | nindent 10 }}
           command: ['sh', '-c', '
             CONFIG_VERSION=$(grep "verify_loculus_version_is:" /package/config/config.yaml | sed "s/verify_loculus_version_is: //;");
diff --git a/kubernetes/loculus/templates/keycloak-database-standin.yaml b/kubernetes/loculus/templates/keycloak-database-standin.yaml
index 0856b47227..4f31156000 100644
--- a/kubernetes/loculus/templates/keycloak-database-standin.yaml
+++ b/kubernetes/loculus/templates/keycloak-database-standin.yaml
@@ -24,7 +24,7 @@ spec:
     spec:
       containers:
         - name: loculus-keycloak-database
-          image: postgres:15.12
+          image: ghcr.io/cloudnative-pg/postgresql@sha256:8e08e8d876545a0ce1cd5aa3c13923181f1d51d419cb618bc52832f4c89fda06
           resources:
             requests:
               memory: "30Mi"
diff --git a/kubernetes/loculus/templates/keycloak-deployment.yaml b/kubernetes/loculus/templates/keycloak-deployment.yaml
index 78bd59233f..f629ca612e 100644
--- a/kubernetes/loculus/templates/keycloak-deployment.yaml
+++ b/kubernetes/loculus/templates/keycloak-deployment.yaml
@@ -36,7 +36,7 @@ spec:
       containers:
         - name: keycloak
           # TODO #1221
-          image: quay.io/keycloak/keycloak:23.0
+          image: ghcr.io/loculus-project/keycloak@sha256:461bdabba2bd2de667b19b0c1831754cb0f1c6c1d1c85cd35ccfa65335078962
           {{- include "loculus.resources" (list "keycloak" $.Values) | nindent 10 }}
           env:
             - name: REGISTRATION_TERMS_MESSAGE
diff --git a/kubernetes/loculus/templates/loculus-database-standin.yaml b/kubernetes/loculus/templates/loculus-database-standin.yaml
index 1324d2827a..8343c23148 100644
--- a/kubernetes/loculus/templates/loculus-database-standin.yaml
+++ b/kubernetes/loculus/templates/loculus-database-standin.yaml
@@ -22,7 +22,7 @@ spec:
     spec:
       containers:
       - name: database
-        image: postgres:15.12
+        image: ghcr.io/cloudnative-pg/postgresql@sha256:8e08e8d876545a0ce1cd5aa3c13923181f1d51d419cb618bc52832f4c89fda06
         args:
           - "-c"
           - "shared_preload_libraries=pg_stat_statements"
diff --git a/kubernetes/loculus/templates/minio-deployment.yaml b/kubernetes/loculus/templates/minio-deployment.yaml
index e18364dd85..87548d1770 100644
--- a/kubernetes/loculus/templates/minio-deployment.yaml
+++ b/kubernetes/loculus/templates/minio-deployment.yaml
@@ -47,7 +47,7 @@ spec:
             name: minio-policies
       containers:
         - name: minio
-          image: minio/minio:latest
+          image: ghcr.io/loculus-project/minio@sha256:9966a92a734f9411e32f4f41d7d9d826fcdc0f68c4e20b70295bd4e7c11f8a2f
           {{- include "loculus.resources" (list "minio" $.Values) | nindent 10 }}
           args: ["server", "/data"]
           ports: