diff --git a/requirements.txt b/requirements.txt
index 098979f6a..e1fb5230f 100644
--- a/requirements.txt
+++ b/requirements.txt
@@ -1093,9 +1093,9 @@ zipp==3.17.0 \
     # via importlib-metadata
 
 # The following packages are considered to be unsafe in a requirements file:
-setuptools==69.0.3 \
-    --hash=sha256:385eb4edd9c9d5c17540511303e39a147ce2fc04bc55289c322b9e5904fe2c05 \
-    --hash=sha256:be1af57fc409f93647f2e8e4573a142ed38724b8cdd389706a867bb4efcf1e78
+setuptools==72.1.0 \
+    --hash=sha256:5a03e1860cf56bb6ef48ce186b0e557fdba433237481a9a625176c2831be15d1 \
+    --hash=sha256:8d243eff56d095e5817f796ede6ae32941278f542e0f941867cc05ae52b162ec
     # via
     #   -r requirements.in
     #   opentelemetry-instrumentation