I noticed playing around with maprando-plando and just changing item locations in the vanilla map, that I could not make a logic step with a progression item in Spore Spawn Super Room after spore spawn, due to it being a one-way and the "don't go a way you can't come back from, except as a last resort"-rule. However, I felt that maybe it could be a venerable exception as a step towards making rooms locked by minibosses less undesirable to check. Haven't really thought about the implications, yet.