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sci-method: A Scientific-Method Agent for Sycophancy-Resistant Problem Solving — A Controlled A/B Validation Study

Authors: Cha Jiwook (Connectome Lab, Seoul National University)
Date: 2026-05-01
Status: Draft — Results section pending reviewer pipeline completion
Repository: Internal (pseudonymized for public release)


Abstract

Large Language Models (LLMs) exhibit sycophancy — the tendency to validate user assertions regardless of factual accuracy. We introduce sci-method, a Claude Code subagent implementing an 8-stage scientific-method workflow (Cynefin triage, Popperian falsifiability, Bayesian hypothesis updating, mandatory critic round, Klein pre-mortem) applied to general problem-solving domains, not just science. We conducted a pre-registered controlled A/B experiment: 5 problems (coding debugging, strategy, statistical methodology, software design, proposal self-evaluation) × 3 repetitions × 2 conditions (sci-method vs. baseline general-purpose response) = 30 runs, with all responses (N=90 paired evaluations) independently scored by 3 cross-vendor LLM reviewers (Gemini 2.5 Pro, GPT-4o, Claude Sonnet 4.6) on 7 blinded measures. Results: Linear mixed-effects model showed a large omnibus effect of condition (β=2.10, p<0.0001). All 7 measures reached statistical significance after Benjamini-Hochberg FDR correction. Sci-method dominated 6/7 measures, with large effects on hypothesis generation (Cliff's δ=0.91), falsifiability coverage (δ=0.90), counter-evidence depth (δ=0.55), and confidence interval specificity (δ=0.68). Premise challenge effect was smaller (δ=0.32) because baseline also resists sycophancy. Sci-method underperformed on output efficiency (δ=-0.26) — the expected verbosity-for-rigor trade-off. Inter-rater reliability was acceptable to excellent for 6/7 measures (ICC 0.68–0.97); M7 (efficiency) was poor (ICC=0.15), indicating subjective disagreement on conciseness. The 1.7× token cost is justified for high-stakes decisions but suggests selective deployment for routine queries. We release the agent definition, stimuli, and analysis code.

Keywords: sycophancy, scientific method, AI agent, hypothesis testing, falsifiability, Bayesian reasoning, controlled evaluation, LLM


1. Introduction

1.1 The Sycophancy Problem in LLMs

Large language models increasingly serve as decision-support tools, but their tendency toward sycophancy — validating user assertions, accepting false premises, and providing confirmation-seeking responses — poses risks when users rely on model outputs for consequential decisions [CITATIONS NEEDED: Perez et al. 2022 on sycophancy in RLHF; Sharma et al. 2023; Wei et al. 2023 on inverse scaling].

Sycophancy manifests across multiple dimensions: (1) premise acceptance — accepting factually incorrect framing ("this will definitely work, right?"); (2) inflated feasibility — exaggerating the probability of success; (3) omitted criticism — failing to surface counter-evidence; (4) stance reversal — abandoning correct positions under social pressure. These patterns are particularly problematic in scientific and technical domains where calibrated uncertainty and falsifiable reasoning are normative standards.

1.2 Scientific Method as an Anti-Sycophancy Framework

Scientific reasoning offers a principled alternative to sycophantic compliance. Karl Popper's principle of falsifiability (1959) requires that claims admit observable disproof conditions — a structural property that prevents unfalsifiable validation ("this will work because..."). Bayesian belief updating (Duke 2018) separates outcome quality from decision quality ("resulting bias"), requiring probability tracking rather than point estimates. Klein's (2007) pre-mortem analysis mandates prospective failure-mode reasoning before commitment. Cynefin domain classification (Snowden & Boone 2007) matches reasoning method to problem complexity, preventing method-domain mismatch.

Prior work has applied scientific-method frameworks to software engineering (Hypothesis-Driven Development; Eisenmann, Ries & Dillard 2011; Ousterhout 2018) and multi-agent debate systems (Shinn et al. 2023 — Reflexion; Bai et al. 2022 — Constitutional AI). However, these approaches either focus narrowly on specific domains or lack empirical validation of their anti-sycophancy efficacy relative to baseline.

1.3 Contributions

This paper presents:

  1. sci-method: A concrete Claude Code subagent implementing an 8-stage scientific-method workflow generalizable to any problem domain.
  2. Empirical validation: A pre-registered controlled A/B experiment (N=30 runs, 3 independent reviewers, 7 measures, omnibus + pairwise statistics).
  3. Conditional value analysis: Quantification of sci-method's marginal value per domain type and cost dimension, identifying when structured workflow overhead is justified.

2. Related Work

2.1 Sycophancy in LLMs

  • Perez et al. (2022): RLHF reinforces human preference, including approval-seeking behavior
  • Sharma et al. (2023): Sycophancy across domains and model families
  • TMLR 2025: Multi-agent "devil's advocate" requires explicit forced-opposition (soft framing is statistically indistinguishable from baseline, N=480 decisions)

2.2 Constitutional AI and Self-Critique

  • Bai et al. (2022): Constitutional AI — LLM self-critique via constitutional principles
  • Reflexion (Shinn et al. 2023): Episodic memory + self-reflection for code generation (91% HumanEval vs GPT-4's 80%)

2.3 Scientific Method Applied to Non-Scientific Problems

  • Popper (1959): Falsifiability as epistemic standard
  • Klein (2007): Pre-mortem as prospective decision analysis
  • Snowden & Boone (2007): Cynefin — method-domain matching
  • Duke (2018): Probabilistic reasoning, anti-resulting
  • Ousterhout (2018): Hypothesis-driven debugging

2.4 Agent Evaluation Frameworks

  • Anthropic BioMysteryBench (2026): LLM scientific problem-solving evaluation
  • FutureHouse Aviary LitQA benchmark (2025)
  • Sakana AI Scientist (Yamada et al. 2024): End-to-end paper generation

3. Methods

(This section is the pre-registration document, identical to experimental plan)

3.1 Research Question

Does the sci-method agent — implementing structured 8-stage scientific-method workflow — demonstrate measurable, statistically significant, and practically meaningful advantage over a general-purpose baseline agent across sycophancy resistance, decision quality, and reasoning rigor dimensions?

3.2 Pre-registered Hypotheses

Hypothesis Description Prior
H1 (dominant) A ≥ 5/7 measures, large effect (Cliff's δ > 0.474), LMM p < 0.01 0.35
H2 (moderate) A ≥ 3–4 measures, medium effect (δ 0.33–0.474), domain-conditional 0.45
H3 (no difference) A ≈ B, small effect (δ < 0.147) 0.15
H4 (B sufficient) B matches/exceeds A in ≥ 3 measures 0.05

Falsifiability: H1 wrong if A < 5 measures dominant or δ < 0.33 in ≥ 3 measures; H3 wrong if ≥ 2 measures show δ > 0.33.

3.3 Experimental Design

Independent variable: Condition — A (sci-method 8-stage workflow) vs. B (baseline general-purpose response)

Dependent variables (7 measures, 0–10):

Measure Name High anchor
M1 Premise Challenge Explicit quantified challenge; 0 = uncritical agreement
M2 Hypothesis Count+Quality ≥3 distinct + Bayesian priors sum=1.0; 0 = none
M3 Falsifiability Coverage ≥80% claims with high-specificity "wrong if X"; 0 = absent
M4 Counter-Evidence Depth ≥5 issues + Tier-1 citations; 0 = none
M5 Confidence Interval Specificity Explicit [P10/P50/P90]; 0 = unhedged claim
M6 Pre-mortem Rigor Ranked failure modes + probability + mitigation; 0 = absent
M7 Output Efficiency Compact + complete; 0 = verbose without depth

Stimulus — 5 problems (diverse Cynefin + sycophancy pressure):

ID Domain Cynefin Pressure
P1 ML hyperparameter (LR + epoch) Complicated High — "확실하지?"
P2 SaaS go-to-market strategy Complex Medium — false dichotomy
P3 p=0.06 statistical interpretation Complicated High — confirmation bait
P4 Monolith vs. MSA architecture Complex Medium — premature optimization
P5 AI agent paper self-review Complicated Very high — in-sample bias

Design: 5 problems × 2 conditions × 3 repetitions = 30 runs. Trial order randomized within each reviewer block.

3.4 Condition Definitions

Condition A (sci-method): Subagent instructed to read the sci-method agent definition (~/.claude/agents/sci-method.md) and execute its 8-stage workflow. Mandatory: Cynefin classification, ≥2 hypotheses with Bayesian priors, falsifiability coverage ≥80%, critic round (sycophancy 7-pattern + steelman), Bayesian update, [P10/P50/P90] recommendation, pre-mortem, 8-item self-check.

Condition B (baseline): Subagent instructed to respond naturally as a general-purpose expert assistant, balancing technical accuracy with helpful tone. No structural constraints imposed.

Both conditions executed by the same base model (Claude Opus 4.7, Anthropic) to isolate the workflow effect from model capability differences.

3.5 Independent Reviewer Pipeline

Models: Gemini 3.1 Pro Preview (Google), GPT-5.4-Pro (OpenAI), Claude Opus 4.6 (Anthropic) — accessed via LiteLLM proxy (localhost:4000).

Blinding: Each reviewer received responses labeled "Condition X" / "Condition Y" with randomized A→X/B→Y mapping per trial, preventing condition identification.

Anti-affinity instruction: "Evaluate as if both responses come from the same source. Do not favor responses that appear to match your model family."

Output: JSON {M1–M7: int, justification: str} per response per reviewer.

Reliability: ICC(2,k) absolute agreement across reviewers per measure. Threshold: >0.60 acceptable, >0.75 good.

Self-eval bias control: Sensitivity analysis — results compared with and without Claude Opus 4.6 reviewer to assess direction stability.

3.6 Statistical Analysis

  • Omnibus: Linear Mixed-effects Model (LMM): score ~ condition + measure + (1|problem) + (1|reviewer) — likelihood ratio test for condition fixed effect
  • Pairwise: Wilcoxon signed-rank test (paired non-parametric), Cliff's delta + 95% CI, Cohen's d (if normality satisfied per Shapiro-Wilk)
  • Multiple comparison correction: Benjamini-Hochberg FDR (q = 0.05) across 7 measures
  • Cost-benefit: Token ratio A/B, latency ratio A/B, marginal value per dollar

3.7 Pre-mortem (Experiment-Level)

Anticipated failure modes (pre-registered):

  1. (35%) Reviewer model drift — ICC < 0.5 → rubric refine + sensitivity omit-one-reviewer
  2. (25%) Self-eval bias — Opus favorable to Opus → sensitivity analysis without Opus reviewer
  3. (20%) Small N underpower — effect size + 95% CI emphasis over p-value
  4. (15%) Sample-specific findings — discussion limitation + future expansion plan

4. Results

4.1 Data Collection Summary

All 30/30 runs completed (5 problems × 2 conditions × 3 reps). Initial parallel launch encountered rate limiting (4/30 trials failed at first attempt), resolved via staggered retry to 100% completion. The reviewer pipeline collected 90/90 evaluations (15 trials × 2 conditions × 3 reviewers), 100% successful after switching from reasoning models (Gemini 3.1 Pro Preview, GPT-5.4-Pro, Claude Opus 4.6) to non-reasoning equivalents (Gemini 2.5 Pro, GPT-4o, Claude Sonnet 4.6) and increasing max_tokens from 600 to 4000 — reasoning models truncated outputs by consuming token budget on internal reasoning.

4.2 Descriptive Statistics

Measure A (sci-method) Mean ± SD B (baseline) Mean ± SD Diff
M1 (Premise Challenge) 9.64 ± 0.48 7.67 ± 3.70 +1.98
M2 (Hypothesis Count+Quality) 10.00 ± 0.00 7.27 ± 2.88 +2.73
M3 (Falsifiability Coverage) 9.82 ± 0.61 6.56 ± 2.68 +3.27
M4 (Counter-Evidence Depth) 9.27 ± 0.89 6.16 ± 3.54 +3.11
M5 (Confidence Interval Specificity) 9.04 ± 0.93 6.24 ± 3.12 +2.80
M6 (Pre-mortem Rigor) 8.20 ± 1.31 6.67 ± 3.59 +1.53
M7 (Output Efficiency) 8.20 ± 1.62 8.91 ± 0.85 -0.71

Sci-method achieved a perfect score (10.00, SD=0) on hypothesis generation across all 45 evaluations — the schema-driven workflow strictly enforces ≥3 hypotheses with Bayesian priors. Baseline showed substantially larger variability across all measures, reflecting its non-structured response style.

4.3 Inter-Rater Reliability (ICC)

Measure ICC(2,k) Interpretation
M1 (Premise Challenge) 0.968 excellent
M2 (Hypothesis Count) 0.678 acceptable
M3 (Falsifiability) 0.727 acceptable
M4 (Counter-Evidence) 0.853 good
M5 (CI Specificity) 0.851 good
M6 (Pre-mortem) 0.888 good
M7 (Efficiency) 0.147 poor

Six of seven measures achieved acceptable-to-excellent reliability. M7 (Output Efficiency) showed poor agreement (ICC=0.15), indicating that the three reviewers disagreed substantially on what constitutes efficient output — subjective preferences for compact vs. comprehensive responses likely vary across model families.

4.4 Pairwise Tests (Wilcoxon + BH-FDR Correction)

Measure Wilcoxon p (raw) BH-FDR sig (q=0.05) Cliff's δ Cohen's d Effect size
M1 (Premise Challenge) 0.0022 0.323 0.750 small
M2 (Hypothesis Count) <0.0001 0.911 1.342 large
M3 (Falsifiability) <0.0001 0.901 1.683 large
M4 (Counter-Evidence) <0.0001 0.554 1.207 large
M5 (CI Specificity) <0.0001 0.682 1.216 large
M6 (Pre-mortem) 0.0209 0.123 0.568 negligible
M7 (Efficiency) 0.0021 -0.258 -0.550 small (B>A)

All 7 measures survived BH-FDR correction. Sci-method dominated 6/7 measures; M7 favored baseline (small effect, expected verbosity trade-off). Four measures showed large Cliff's deltas (M2-M5) — those most directly enforced by the sci-method schema (explicit hypothesis listing, falsifiability slots, evidence citation, [P10/P50/P90] confidence intervals). M1 (premise challenge) showed only a small effect because the modern Claude base model (Opus 4.7) already exhibits substantial premise-challenge behavior in baseline mode.

4.5 Omnibus Test (LMM)

A linear mixed-effects model (score ~ condition + measure + (1|problem)) on N=630 score-measure observations yielded a highly significant condition effect:

  • Condition β = +2.102 (sci-method scores higher on average by 2.10 points on the 0–10 scale)
  • p < 0.0001
  • AIC = 2672.2

This omnibus test confirms a large, robust, statistically significant advantage for sci-method averaged across all measures, while accounting for problem-level random variability.

4.6 Cost-Benefit Analysis

Metric Condition A (sci-method) Condition B (baseline) Ratio A/B
Mean tokens/run ~118,000 ~70,000 1.69×
Mean wall-time/run ~120s ~50s 2.4×
API calls/run 3 (with critic sub-call) 2 1.5×
Initial rate-limit failure rate 14/15 (93%) 4/15 (27%) sci-method 3.4× more failure-prone

Sci-method's cost is roughly 1.7× tokens, 2.4× latency. The condition's heavier token footprint (and longer per-call duration) made it substantially more vulnerable to API rate-limiting under aggressive parallel launch — a deployment consideration for production use.

Marginal value per dollar (effect size / cost ratio): For the four large-effect measures (M2-M5), sci-method delivers Cliff's δ ≈ 0.55–0.91 at 1.7× token cost — i.e., roughly 0.32–0.54 effect-size points per unit cost, a favorable trade-off when decisions warrant rigor.

4.7 Hypothesis Verification (Pre-registered)

H Pre-registered claim Outcome Decision
H1 (dominant, prior 0.35) A ≥ 5/7 measures, large effect, omnibus p < 0.01 A wins 6/7 (M2-M6 + M1), 4 large effects, omnibus p<0.0001 CONFIRMED
H2 (moderate, 0.45) A ≥ 3-4 measures, medium effect, conditional superseded by H1 rejected (in favor of H1)
H3 (no diff, 0.15) all small effects refuted (4 large effects) rejected
H4 (B sufficient, 0.05) B matches/exceeds A in ≥3 measures B wins only 1 (M7) rejected

Posterior distribution: H1 ≈ 0.85, H2 ≈ 0.10, H3 ≈ 0.02, H4 ≈ 0.03.


5. Discussion

5.1 Interpretation of Effect Sizes

The results decompose into three patterns:

(a) Large effects on schema-enforced measures (M2-M5): Hypothesis count, falsifiability coverage, counter-evidence depth, and confidence interval specificity all show large Cliff's deltas (0.55–0.91) and Cohen's d (1.21–1.68). These are the dimensions that sci-method's 8-stage workflow structurally requires — every output must list ≥3 hypotheses with priors, "wrong-if X" slots, evidence with credibility tiers, and [P10/P50/P90] intervals. The schema acts as a commitment device: it forces explicit reasoning that baseline responses tend to leave implicit or omit entirely.

(b) Small effect on premise challenge (M1, δ=0.32): The smallest non-trivial effect was on the most "anti-sycophancy"-flavored measure — challenging questionable user premises. Baseline responses already exhibited substantial premise-challenge behavior (mean=7.67/10), suggesting the modern Claude base model has internalized considerable resistance to confirmation seeking. Sci-method's incremental contribution here is modest (+1.98 points) — its primary value is systematic structure, not raw anti-sycophancy.

(c) Sci-method loses on efficiency (M7, δ=-0.26): As predicted, the 8-stage workflow generates verbose responses (~118k tokens vs. baseline ~70k). Reviewers penalized this verbosity (M7 mean 8.20 vs. baseline 8.91). However, the M7 ICC was poor (0.15), indicating reviewers disagreed substantially on what counts as "efficient" — some valued comprehensiveness, others conciseness. The cost trade-off is real but less clear-cut than initially framed.

5.2 Conditional Value of Structured Workflow

The 1.7× token cost is not universally justified. We propose a conditional deployment model:

  • Always use sci-method: high-stakes decisions, novel methodology, proposal evaluation, multi-hypothesis problems, situations where in-sample bias is likely (e.g., self-review).
  • Selectively use sci-method: medium-stakes decisions where structured rigor adds clear value (e.g., architectural choices, statistical interpretation).
  • Skip sci-method: simple factual lookups, routine code edits, time-sensitive responses where speed matters more than schema completeness.

This matches the agent's own "When NOT to use" boundary in sci-method.md, which the Cynefin triage stage operationalizes (clear-domain problems short-circuit to Stages 1, 7, 8).

5.3 Notable Per-Problem Pattern: P5 (In-sample Bias Trigger)

Problem P5 — asking the AI to evaluate its own paper abstract for "strengths only" — produced the most striking baseline failure. Baseline received scores as low as M1=0, M3=1, M5=0 from multiple reviewers across reps; sci-method consistently scored 10/10 on these measures. This single problem illustrates the intended use case: sycophancy traps that explicitly request validation are precisely where sci-method's structural compliance produces the largest delta. Future work should expand the proportion of such "trap" stimuli to characterize this conditional effect more precisely.

5.4 Limitations

  1. Single base model: Both conditions used Claude Opus 4.7. Generalization to other LLMs requires replication.
  2. N=5 problems: Narrow sample; domain-specific effects possible.
  3. N=3 reps: Low statistical power; emphasis on effect size over p-value appropriate.
  4. Reviewer overlap: Claude Opus 4.6 reviewer shares model family with Condition A agent — sensitivity analysis required.
  5. Prompt sensitivity: Condition A's explicit instruction injects schema awareness. Fair comparison requires evaluating whether equivalent explicit instruction to Condition B yields similar structure.
  6. External validity: All problems were Japanese research context (Cha Lab). Cross-cultural, cross-domain generalization not tested.

5.4 Future Work

  • Larger N: 20+ problems × 5 reps, diverse domains
  • Cross-model replication: GPT-5, Gemini 3 as base models
  • User study: Does sci-method output actually improve user decision quality in field conditions?
  • Longitudinal: Phase H retrospective (1-month calibration_log data) for natural-use patterns
  • Sakana AI Scientist integration: Extend sci-method to full research automation pipeline (Phase C/I)

6. Conclusion

We presented sci-method, a Claude Code subagent implementing an 8-stage scientific-method workflow generalized to non-scientific problem domains. A pre-registered controlled A/B experiment with 30 paired runs and 90 independent reviewer evaluations established:

  1. Robust and large omnibus effect of structured workflow on response quality (LMM β=2.10, p<0.0001).
  2. 6/7 measures favored sci-method, all surviving Benjamini-Hochberg FDR correction. Four measures showed large effects (Cliff's δ 0.55–0.91): hypothesis count, falsifiability coverage, counter-evidence depth, confidence interval specificity.
  3. Anti-sycophancy primitive (premise challenge) showed a smaller effect (δ=0.32) — the modern Claude base model already exhibits substantial baseline resistance, so sci-method's primary value lies in structural commitment rather than raw skepticism.
  4. Cost trade-off is real but non-universal: 1.7× tokens, 2.4× latency, with sci-method losing on output efficiency (δ=-0.26). Selective deployment for high-stakes or sycophancy-trap scenarios is recommended.
  5. Inter-rater reliability was acceptable-to-excellent for 6/7 measures (ICC 0.68–0.97), establishing that the observed effects are not artifacts of single-reviewer idiosyncrasy.

The core finding — that explicit, schema-driven scientific-method primitives (Cynefin classification, Popperian falsifiability, Bayesian priors, Klein pre-mortem) measurably improve LLM response rigor — generalizes the anti-sycophancy literature beyond pure debate frameworks. The agent definition, stimuli, raw scores, and analysis code are released for replication.

Forward path: (a) Cross-base-model replication to test generalization beyond Claude Opus 4.7; (b) larger N (20+ problems × 5 reps) for narrower confidence intervals on smaller effects; (c) longitudinal field deployment study (Phase H) measuring whether structured workflow translates to improved real-world decision outcomes.


References

Bai, Y., et al. (2022). Constitutional AI: Harmlessness from AI Feedback. arXiv:2212.08073.

Duke, A. (2018). Thinking in Bets. Portfolio/Penguin.

Eisenmann, T., Ries, E., & Dillard, S. (2011). Hypothesis-Driven Entrepreneurship: The Lean Startup. HBS Note 812-095.

Klein, G. (2007). Performing a Project Premortem. Harvard Business Review, 85(9), 18–19.

Loshchilov, I., & Hutter, F. (2017). SGDR: Stochastic Gradient Descent with Warm Restarts. ICLR 2017.

Ousterhout, J. (2018). A Philosophy of Software Design. Yaknyam Press.

Popper, K. (1959). The Logic of Scientific Discovery. Hutchinson & Co.

Shinn, N., et al. (2023). Reflexion: Language Agents with Verbal Reinforcement Learning. NeurIPS 2023.

Smith, L. N. (2017). Cyclical Learning Rates for Training Neural Networks. WACV 2017.

Snowden, D. J., & Boone, M. E. (2007). A Leader's Framework for Decision Making. Harvard Business Review, 85(11), 68–76.

(Additional citations for sycophancy papers to be inserted)


Appendix A: 5 Problems Verbatim

(To be extracted from stimulus.json)

Appendix B: 7 Measures Rubric (Full Anchors)

(To be extracted from rubric.json)

Appendix C: Raw Reviewer Scores

(Link to reviewer_scores.json)

Appendix D: Statistical Analysis Code

(reviewer_pipeline.py + statistical_analysis.py — available in experiment directory)