diff --git a/app/Http/Requests/Rest/SearchRequest.php b/app/Http/Requests/Rest/SearchRequest.php
new file mode 100644
index 00000000..5067dc50
--- /dev/null
+++ b/app/Http/Requests/Rest/SearchRequest.php
@@ -0,0 +1,18 @@
+<?php
+
+namespace App\Http\Requests\Rest;
+
+use App\Rules\Search\Search;
+use Lomkit\Rest\Http\Requests\SearchRequest as LomkitSearchRequest;
+
+class SearchRequest extends LomkitSearchRequest
+{
+    public function rules(): array
+    {
+        $resource = $this->route()->controller::newResource();
+
+        return [
+            'search' => (new Search)->setResource($resource),
+        ];
+    }
+}
diff --git a/app/Providers/AppServiceProvider.php b/app/Providers/AppServiceProvider.php
index 5dd94818..bb941d8c 100644
--- a/app/Providers/AppServiceProvider.php
+++ b/app/Providers/AppServiceProvider.php
@@ -2,6 +2,7 @@
 
 namespace App\Providers;
 
+use App\Http\Requests\Rest\SearchRequest as AppSearchRequest;
 use App\Models\Citation;
 use App\Models\Collection;
 use App\Models\GeoLocation;
@@ -22,13 +23,17 @@
 use Illuminate\Support\Facades\URL;
 use Illuminate\Support\Facades\Vite;
 use Illuminate\Support\ServiceProvider;
+use Lomkit\Rest\Http\Requests\SearchRequest;
 
 class AppServiceProvider extends ServiceProvider
 {
     /**
      * Register any application services.
      */
-    public function register(): void {}
+    public function register(): void
+    {
+        $this->app->extend(SearchRequest::class, fn ($resolved, $app) => $app->make(AppSearchRequest::class));
+    }
 
     /**
      * Bootstrap any application services.
diff --git a/app/Rules/Search/Search.php b/app/Rules/Search/Search.php
new file mode 100644
index 00000000..ef4e88be
--- /dev/null
+++ b/app/Rules/Search/Search.php
@@ -0,0 +1,16 @@
+<?php
+
+namespace App\Rules\Search;
+
+use Lomkit\Rest\Rules\Search\Search as BaseSearch;
+
+class Search extends BaseSearch
+{
+    public function buildValidationRules(string $attribute, mixed $value): array
+    {
+        $rules = parent::buildValidationRules($attribute, $value);
+        $rules[$attribute.'.filters.*'] = (new SearchFilter)->setResource($this->resource);
+
+        return $rules;
+    }
+}
diff --git a/app/Rules/Search/SearchFilter.php b/app/Rules/Search/SearchFilter.php
new file mode 100644
index 00000000..7187416a
--- /dev/null
+++ b/app/Rules/Search/SearchFilter.php
@@ -0,0 +1,60 @@
+<?php
+
+namespace App\Rules\Search;
+
+use Illuminate\Validation\Rule;
+use Lomkit\Rest\Http\Requests\RestRequest;
+use Lomkit\Rest\Rules\Resource\ResourceFieldOrNested;
+use Lomkit\Rest\Rules\Search\SearchFilter as BaseSearchFilter;
+
+class SearchFilter extends BaseSearchFilter
+{
+    public function buildValidationRules(string $attribute, mixed $value): array
+    {
+        $request = app(RestRequest::class);
+        $isScoutMode = $request->isScoutMode();
+
+        $fieldsValidation = $isScoutMode ?
+            Rule::in($this->resource->getScoutFields($request)) :
+            (new ResourceFieldOrNested)->setResource($this->resource);
+
+        $allowedOperators = $isScoutMode ?
+            ['=', 'in', 'not in'] :
+            ['=', '!=', '>', '>=', '<', '<=', 'like', 'ilike', 'not like', 'in', 'not in'];
+
+        return [
+            $attribute.'.field' => [
+                'string',
+                'required_without:'.$attribute.'.nested',
+                $fieldsValidation,
+            ],
+            $attribute.'.nested' => ! $isScoutMode ? [
+                'sometimes',
+                'prohibits:'.$attribute.'.field,operator,value',
+                'array',
+            ] : [
+                'prohibited',
+            ],
+            $attribute.'.nested.*.nested' => [
+                'prohibited',
+            ],
+            $attribute.'.nested.*' => [
+                (new SearchFilter)->setResource($this->resource),
+            ],
+            $attribute.'.operator' => [
+                'string',
+                Rule::in($allowedOperators),
+            ],
+            $attribute.'.type' => ! $isScoutMode ? [
+                'sometimes',
+                Rule::in(['or', 'and']),
+            ] : [
+                'prohibited',
+            ],
+            $attribute.'.value' => [
+                'exclude_if:'.$attribute.'.value,null',
+                'required_without:'.$attribute.'.nested',
+            ],
+        ];
+    }
+}
diff --git a/tests/Feature/Rest/MoleculeSearchIlikeTest.php b/tests/Feature/Rest/MoleculeSearchIlikeTest.php
new file mode 100644
index 00000000..b10c9587
--- /dev/null
+++ b/tests/Feature/Rest/MoleculeSearchIlikeTest.php
@@ -0,0 +1,72 @@
+<?php
+
+namespace Tests\Feature\Rest;
+
+use App\Models\Molecule;
+use App\Models\User;
+use Illuminate\Foundation\Testing\RefreshDatabase;
+use Tests\TestCase;
+
+class MoleculeSearchIlikeTest extends TestCase
+{
+    use RefreshDatabase;
+
+    public function test_molecule_search_accepts_ilike_filter_for_case_insensitive_match(): void
+    {
+        $user = User::factory()->create();
+
+        Molecule::create([
+            'identifier' => 'CNP9999001.0',
+            'name' => 'Caffeine',
+            'active' => true,
+        ]);
+
+        $response = $this->actingAs($user, 'sanctum')->postJson('/api/molecules/search', [
+            'search' => [
+                'filters' => [
+                    ['field' => 'name', 'operator' => 'ilike', 'value' => '%caffeine%'],
+                ],
+            ],
+        ]);
+
+        $response->assertOk();
+        $response->assertJsonPath('data.0.name', 'Caffeine');
+    }
+
+    public function test_molecule_search_like_filter_remains_case_sensitive(): void
+    {
+        $user = User::factory()->create();
+
+        Molecule::create([
+            'identifier' => 'CNP9999001.0',
+            'name' => 'Caffeine',
+            'active' => true,
+        ]);
+
+        $response = $this->actingAs($user, 'sanctum')->postJson('/api/molecules/search', [
+            'search' => [
+                'filters' => [
+                    ['field' => 'name', 'operator' => 'like', 'value' => '%caffeine%'],
+                ],
+            ],
+        ]);
+
+        $response->assertOk();
+        $response->assertJsonPath('data', []);
+    }
+
+    public function test_molecule_search_rejects_unknown_filter_operator(): void
+    {
+        $user = User::factory()->create();
+
+        $response = $this->actingAs($user, 'sanctum')->postJson('/api/molecules/search', [
+            'search' => [
+                'filters' => [
+                    ['field' => 'name', 'operator' => 'invalid', 'value' => '%caffeine%'],
+                ],
+            ],
+        ]);
+
+        $response->assertUnprocessable();
+    }
+}