ico-base.owl

<?xml version="1.0"?>
<rdf:RDF xmlns="http://purl.obolibrary.org/obo/ico.owl#"
     xml:base="http://purl.obolibrary.org/obo/ico.owl"
     xmlns:dc="http://purl.org/dc/elements/1.1/"
     xmlns:obo="http://purl.obolibrary.org/obo/"
     xmlns:owl="http://www.w3.org/2002/07/owl#"
     xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
     xmlns:xml="http://www.w3.org/XML/1998/namespace"
     xmlns:xsd="http://www.w3.org/2001/XMLSchema#"
     xmlns:cito="http://purl.org/spar/cito/"
     xmlns:doap="http://usefulinc.com/ns/doap#"
     xmlns:foaf="http://xmlns.com/foaf/0.1/"
     xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#"
     xmlns:skos="http://www.w3.org/2004/02/skos/core#"
     xmlns:swrl="http://www.w3.org/2003/11/swrl#"
     xmlns:rdfs1="rdfs:"
     xmlns:swrla="http://swrl.stanford.edu/ontologies/3.3/swrla.owl#"
     xmlns:swrlb="http://www.w3.org/2003/11/swrlb#"
     xmlns:terms="http://purl.org/dc/terms/"
     xmlns:protege="http://protege.stanford.edu/plugins/owl/protege#"
     xmlns:subsets="http://purl.obolibrary.org/obo/ro/subsets#"
     xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#">
    <owl:Ontology rdf:about="http://purl.obolibrary.org/obo/ico.owl">
        <owl:versionIRI rdf:resource="http://purl.obolibrary.org/obo/ico/releases/2026-02-28/ico.owl"/>
        <dc:contributor xml:lang="en">Anna Maria Masci</dc:contributor>
        <dc:contributor xml:lang="en">Chris Stoeckert</dc:contributor>
        <dc:contributor xml:lang="en">Cui Tao</dc:contributor>
        <dc:contributor xml:lang="en">Helena Ellis</dc:contributor>
        <dc:contributor xml:lang="en">Jian Guan</dc:contributor>
        <dc:contributor xml:lang="en">Jihad Obeid</dc:contributor>
        <dc:contributor xml:lang="en">Jonathan Bona</dc:contributor>
        <dc:contributor xml:lang="en">Mathias Brochhausen</dc:contributor>
        <dc:contributor xml:lang="en">William Duncan</dc:contributor>
        <dc:creator xml:lang="en">Alla Karnovsky</dc:creator>
        <dc:creator xml:lang="en">Asiyah Yu Lin</dc:creator>
        <dc:creator xml:lang="en">Christoph Brochhausen</dc:creator>
        <dc:creator xml:lang="en">Cooper Stansbury</dc:creator>
        <dc:creator xml:lang="en">Elizabeth Eisenhauer</dc:creator>
        <dc:creator xml:lang="en">Elizabeth Umberfield</dc:creator>
        <dc:creator xml:lang="en">Frank Manion</dc:creator>
        <dc:creator xml:lang="en">J. Neil Otte</dc:creator>
        <dc:creator xml:lang="en">Jie Zheng</dc:creator>
        <dc:creator xml:lang="en">Jonathan Vajda</dc:creator>
        <dc:creator xml:lang="en">Kathleen Ford</dc:creator>
        <dc:creator xml:lang="en">Marcy Harris</dc:creator>
        <dc:creator>Rahma Alifia</dc:creator>
        <dc:creator>Tuan Amith</dc:creator>
        <dc:creator xml:lang="en">Yongqun &quot;Oliver&quot; He</dc:creator>
        <dc:description xml:lang="en">The Informed Consent Ontology (ICO) is an ontology for the informed consent and informed consent process in the medical field.</dc:description>
        <dc:title xml:lang="en">Informed Consent Ontology (ICO)</dc:title>
        <terms:license rdf:resource="http://creativecommons.org/licenses/by/4.0/"/>
        <rdfs:comment xml:lang="en">Terms were identified from a sample of informed consent templates, and definitions were selected based on concordance between the defintion and the use of the term in the source informed consent template document.  We preferentially selected defintioins from the NCI thesuarus.</rdfs:comment>
        <rdfs:seeAlso rdf:resource="https://github.com/ICO-ontology/ICO"/>
        <owl:versionInfo>2026-02-28</owl:versionInfo>
    </owl:Ontology>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Annotation properties
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://purl.obolibrary.org/obo/IAO_0000112 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000112"/>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0000115 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000115"/>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0000116 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000116"/>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0000117 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000117"/>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0000118 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000118"/>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0000119 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000119"/>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0000232 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000232"/>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0000233 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000233"/>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0000425 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000425"/>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0000600 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000600"/>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000091 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/ICO_0000091">
        <rdfs:label xml:lang="en">term_mapping_to_UMLS</rdfs:label>
        <rdfs:subPropertyOf rdf:resource="http://www.w3.org/2000/01/rdf-schema#seeAlso"/>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000092 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/ICO_0000092">
        <rdfs:label xml:lang="en">term_mapping_to_NCIT</rdfs:label>
        <rdfs:subPropertyOf rdf:resource="http://www.w3.org/2000/01/rdf-schema#seeAlso"/>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000093 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/ICO_0000093">
        <rdfs:label xml:lang="en">term_mapping_to_HL7v3</rdfs:label>
        <rdfs:subPropertyOf rdf:resource="http://www.w3.org/2000/01/rdf-schema#seeAlso"/>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000321 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/ICO_0000321">
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury</obo:IAO_0000117>
        <obo:IAO_0000232 xml:lang="en">This annotation property specifies classes that were developed as part of an alignment effort between the Common Rule Ontology and the Informed Consent Ontology in the Summer of 2018. These classes represent entities that are necessary for understanding the regularatory frameworks that influence informed consent, often at a different level of granularity than individual consent processes. These classes were created to be compatible with regulatory frameworks outside the Unitied States, hence they are general.</obo:IAO_0000232>
        <rdfs:label xml:lang="en">RUBRIC</rdfs:label>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000404 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/ICO_0000404">
        <rdfs:comment xml:lang="en">All classes and properties with this annotation are members of the PICO grammar.</rdfs:comment>
        <rdfs:label xml:lang="en">PICO CLASS</rdfs:label>
    </owl:AnnotationProperty>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000420 -->

    <owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/ICO_0000420">
        <rdfs:label xml:lang="en">Merriam-Webster Definition</rdfs:label>
    </owl:AnnotationProperty>
    


    <!-- http://purl.org/dc/elements/1.1/contributor -->

    <owl:AnnotationProperty rdf:about="http://purl.org/dc/elements/1.1/contributor"/>
    


    <!-- http://purl.org/dc/elements/1.1/creator -->

    <owl:AnnotationProperty rdf:about="http://purl.org/dc/elements/1.1/creator"/>
    


    <!-- http://purl.org/dc/elements/1.1/date -->

    <owl:AnnotationProperty rdf:about="http://purl.org/dc/elements/1.1/date"/>
    


    <!-- http://purl.org/dc/elements/1.1/description -->

    <owl:AnnotationProperty rdf:about="http://purl.org/dc/elements/1.1/description"/>
    


    <!-- http://purl.org/dc/elements/1.1/title -->

    <owl:AnnotationProperty rdf:about="http://purl.org/dc/elements/1.1/title"/>
    


    <!-- http://purl.org/dc/terms/license -->

    <owl:AnnotationProperty rdf:about="http://purl.org/dc/terms/license"/>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Object Properties
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://purl.obolibrary.org/obo/BFO_0000050 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/BFO_0000050"/>
    


    <!-- http://purl.obolibrary.org/obo/BFO_0000051 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/BFO_0000051"/>
    


    <!-- http://purl.obolibrary.org/obo/BFO_0000054 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/BFO_0000054"/>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0000219 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000219"/>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000067 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/ICO_0000067">
        <rdfs:subPropertyOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteProperty"/>
        <obo:IAO_0000115 xml:lang="en">An object property that represents a relation between a form and the person or organization who acts as a signer and signs the form.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Yongqun He, Elizabeth Eisenhauer</obo:IAO_0000117>
        <rdfs:label>obsolete form signed by</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000130 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/ICO_0000130">
        <rdfs:subPropertyOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteProperty"/>
        <rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/ICO_0000001"/>
        <rdfs:range rdf:resource="http://purl.obolibrary.org/obo/ICO_0000111"/>
        <obo:IAO_0000115 xml:lang="en">A relation that links an informed consent form to an associated IRB number.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Elizabeth Eisenhauer, Yongqun He, Asiyah Yu Lin, Alla Karnovsky, Marcy Harris</obo:IAO_0000117>
        <rdfs:label>obsolete is associated with review board approval number</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000132 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/ICO_0000132">
        <rdfs:subPropertyOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteProperty"/>
        <obo:IAO_0000115 xml:lang="en">An object property that represents a relation between a unique identifier (ID) and an organization that assigns the ID.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Yongqun He, Elizabeth Eisenhauer, Asiyah Yu Lin, Alla Karnovsky, Marcy Harris</obo:IAO_0000117>
        <rdfs:label>obsolete is assigned by organization</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000183 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/ICO_0000183">
        <obo:IAO_0000115>Relates a process to a time-measurement-datum that represents the duration of the process</obo:IAO_0000115>
        <obo:IAO_0000116>BCGO is obsolete, and so here we add a new term to replace the term originally defined in BCGO. In long term, we will need to submit this term to RO.</obo:IAO_0000116>
        <obo:IAO_0000117>Jie Zheng, Rahma Alifia, Tuan Amith, Oliver He</obo:IAO_0000117>
        <obo:IAO_0000119>http://purl.obolibrary.org/obo/BCGO_0000182</obo:IAO_0000119>
        <obo:IAO_0000233>https://github.com/ICO-ontology/ICO/issues/38</obo:IAO_0000233>
        <rdfs:label xml:lang="en">has duration</rdfs:label>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000208 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/ICO_0000208">
        <rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/OBI_0000066"/>
        <rdfs:range rdf:resource="http://purl.obolibrary.org/obo/IAO_0000030"/>
        <obo:IAO_0000115>An object property that represents a relation between a research project and its associated permission type under the categery of &apos;information content entity&apos;.</obo:IAO_0000115>
        <obo:IAO_0000117>Jie Zheng, Rahma Alifia, Tuan Amith, Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>has_permission</obo:IAO_0000118>
        <rdfs:label xml:lang="en">has permission</rdfs:label>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000216 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/ICO_0000216">
        <rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000054"/>
        <obo:IAO_0000115 xml:lang="en">A relation holding between an instance of a deontic role and an instance of an intentional action when the deontic role bearer participates in the intentional action and is allowed to do so.</obo:IAO_0000115>
        <rdfs:label xml:lang="en">permits</rdfs:label>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000224 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/ICO_0000224">
        <rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0000057"/>
        <owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000225"/>
        <obo:IAO_0000117 xml:lang="en">J. Neil Otte, Jonathan Vajda, Cooper Stansbury</obo:IAO_0000117>
        <rdfs:comment xml:lang="en">A relation between an instance of Process and an instance of Continuant, where the continuant is a causal participant in the process.</rdfs:comment>
        <rdfs:label xml:lang="en">has agent</rdfs:label>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000225 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/ICO_0000225">
        <rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0000056"/>
        <obo:IAO_0000115 xml:lang="en">A relation between a continuant and a process, where the continuant is a causal participant in the process.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">J. Neil Otte, Jonathan Vajda, Cooper Stansbury</obo:IAO_0000117>
        <rdfs:label xml:lang="en">agent in</rdfs:label>
    </owl:ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/OBI_0000299 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/OBI_0000299"/>
    


    <!-- http://purl.obolibrary.org/obo/RO_0000052 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0000052"/>
    


    <!-- http://purl.obolibrary.org/obo/RO_0000053 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0000053"/>
    


    <!-- http://purl.obolibrary.org/obo/RO_0000056 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0000056"/>
    


    <!-- http://purl.obolibrary.org/obo/RO_0000057 -->

    <owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0000057"/>
    


    <!-- http://www.geneontology.org/formats/oboInOwl#ObsoleteProperty -->

    <owl:ObjectProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#ObsoleteProperty"/>
    


    <!-- http://www.ontologyrepository.com/CommonCoreOntologies/prescribes -->

    <owl:ObjectProperty rdf:about="http://www.ontologyrepository.com/CommonCoreOntologies/prescribes"/>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Classes
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://purl.obolibrary.org/obo/BFO_0000008 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000008"/>
    


    <!-- http://purl.obolibrary.org/obo/BFO_0000015 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000015"/>
    


    <!-- http://purl.obolibrary.org/obo/BFO_0000016 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000016"/>
    


    <!-- http://purl.obolibrary.org/obo/BFO_0000023 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000023"/>
    


    <!-- http://purl.obolibrary.org/obo/BFO_0000029 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000029"/>
    


    <!-- http://purl.obolibrary.org/obo/BFO_0000030 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000030"/>
    


    <!-- http://purl.obolibrary.org/obo/BFO_0000034 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000034"/>
    


    <!-- http://purl.obolibrary.org/obo/BFO_0000038 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000038"/>
    


    <!-- http://purl.obolibrary.org/obo/BFO_0000040 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/BFO_0000040"/>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0000001 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0000001"/>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0000005 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0000005"/>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0000027 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0000027"/>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0000028 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0000028"/>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0000030 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0000030"/>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0000033 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0000033"/>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0000055 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0000055"/>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0000104 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0000104"/>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0000109 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0000109"/>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0000300 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0000300"/>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0000310 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0000310"/>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0000314 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0000314"/>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0021003 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0021003"/>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0021007 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0021007"/>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0021008 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0021008"/>
    


    <!-- http://purl.obolibrary.org/obo/IAO_0021009 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/IAO_0021009"/>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000001 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000001">
        <owl:equivalentClass>
            <owl:Class>
                <owl:unionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/ICO_0000213"/>
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/ICO_0000214"/>
                </owl:unionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0021007"/>
        <obo:IAO_0000115 xml:lang="en">A document that explains all relevant information to assist a human being in understanding the expectations and requirements of participation in a process, and is an instrument in obtaining consent and, after having obtained consent, is a record that such a consent has occurred.</obo:IAO_0000115>
        <obo:IAO_0000116 xml:lang="en">The term definition is adapted from NCIt definition of &apos;consent form&apos; (C16468) with modification. For instance, whereas the NCIt definition restricted informed consent forms to clinical trials, the present definition does not.</obo:IAO_0000116>
        <obo:IAO_0000117 xml:lang="en"></obo:IAO_0000117>
        <obo:IAO_0000117 xml:lang="en">Alla Karnovsky, Frank Manion, Yongqun He, Asiyah Yu Lin, Marcy Harris, Elizabeth Eisenhauer, Jonathan Vajda, Cooper Stansbury, J. Neil Otte</obo:IAO_0000117>
        <obo:IAO_0000118 xml:lang="en">informed consent document</obo:IAO_0000118>
        <obo:IAO_0000119 xml:lang="en">NCIt C16468</obo:IAO_0000119>
        <obo:IAO_0000232 xml:lang="en">See curator note for &apos;incomplete informed consent form&apos;.</obo:IAO_0000232>
        <obo:ICO_0000091 xml:lang="en">C0009797</obo:ICO_0000091>
        <obo:ICO_0000092 xml:lang="en">C16468</obo:ICO_0000092>
        <rdfs:label xml:lang="en">informed consent form</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000002 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000002">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
        <obo:IAO_0000115 xml:lang="en">A planned process that involves the design of an informed consent form.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Alla Karnovsky, Frank Manion, Yongqun He</obo:IAO_0000117>
        <obo:IAO_0000232 xml:lang="en">This class is under group discussion as of 03/26/2019.</obo:IAO_0000232>
        <rdfs:label xml:lang="en">designing an informed consent form</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000003 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000003">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
        <obo:IAO_0000115 xml:lang="en">A planned process that validates an informed consent form.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Alla Karnovsky, Frank Manion, Yongqun He</obo:IAO_0000117>
        <rdfs:label xml:lang="en">validating an informed consent form</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000004 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000004">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
        <obo:IAO_0000115 xml:lang="en">A planned process that approves an informed consent form.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Alla Karnovsky, Frank Manion, Yongqun He</obo:IAO_0000117>
        <rdfs:label xml:lang="en">approving an informed consent form</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000005 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000005">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0021003"/>
        <obo:IAO_0000115 xml:lang="en">A social act that is a part of an informed consent process and has output of a signed informed consent form. The signing process leads to a legal obligation.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Alla Karnovsky, Frank Manion, Yongqun He, Jihad Obeid, Chris Stoeckert, and Mathias Brochhausen</obo:IAO_0000117>
        <obo:IAO_0000232 xml:lang="en">This class is under group discussion as of 03/26/2019.</obo:IAO_0000232>
        <rdfs:comment xml:lang="en">Signing here does not mean that we have to sign with a pen. It may happen in terms of signing a piece of a paper or an electronic form.</rdfs:comment>
        <rdfs:label xml:lang="en">signing an informed consent form</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000006 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000006">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000245"/>
        <obo:IAO_0000115 xml:lang="en">An organization charged with approving clinical study protocols and ensuring that applicable governing rules and laws are upheld.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Alla Karnovsky, Frank Manion, Yongqun He</obo:IAO_0000117>
        <obo:IAO_0000232 xml:lang="en">This class is under group discussion as of 03/26/2019.</obo:IAO_0000232>
        <rdfs:label xml:lang="en">informed consent regulatory body</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000007 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000007">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000314"/>
        <obo:IAO_0000115 xml:lang="en">A document that is a part of an informed consent form.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Alla Karnovsky, Frank Manion, Yongqun He</obo:IAO_0000117>
        <obo:IAO_0000118 xml:lang="en">informed consent form element</obo:IAO_0000118>
        <obo:IAO_0000232 xml:lang="en">This class is under group discussion as of 03/26/2019.</obo:IAO_0000232>
        <rdfs:label xml:lang="en">part of informed consent form</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000008 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000008">
        <rdfs:subClassOf rdf:resource="http://www.ontologyrepository.com/CommonCoreOntologies/DescriptiveInformationContentEntity"/>
        <obo:IAO_0000115 xml:lang="en">A descriptive information content entity that describes potential harm or estimates the likelihood of harm.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Alla Karnovsky, Frank Manion, Yongqun He, Cooper Stansbury</obo:IAO_0000117>
        <rdfs:label xml:lang="en">description of participation risk</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000009 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000009">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000033"/>
        <obo:IAO_0000115 xml:lang="en">A document part that prescribes a method of contact in the future.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Alla Karnovsky, Frank Manion, Yongqun He, Cooper Stansbury</obo:IAO_0000117>
        <rdfs:label xml:lang="en">recontact method directive</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000010 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000010">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000242"/>
        <obo:IAO_0000115 xml:lang="en">An answer directive that is part of a document and whose filling in or leaving blank is incidental to the completion of the form.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Alla Karnovsky, Frank Manion, Yongqun He, J. Neil Otte</obo:IAO_0000117>
        <rdfs:label>option to check</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000011 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000011">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000314"/>
        <obo:IAO_0000115 xml:lang="en">A document part of an informed consent form for which an answer is required in order to complete the form.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Alla Karnovsky, Frank Manion, Yongqun He, J. Neil Otte</obo:IAO_0000117>
        <obo:IAO_0000232 xml:lang="en">This class is under group discussion as of 03/26/2019.</obo:IAO_0000232>
        <rdfs:label xml:lang="en">required informed consent element</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000012 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000012">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000314"/>
        <obo:IAO_0000115 xml:lang="en">A document part of an informed consent form for which an answer is not required in order to complete the form.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Alla Karnovsky, Frank Manion, Yongqun He, J. Neil Otte</obo:IAO_0000117>
        <obo:IAO_0000232 xml:lang="en">This class is under group discussion as of 03/26/2019.</obo:IAO_0000232>
        <rdfs:label xml:lang="en">optional informed consent element</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000013 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000013">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000001"/>
        <obo:IAO_0000115 xml:lang="en">An informed consent form that documents a voluntary decision to deposit a human biospecimen.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Alla Karnovsky, Frank Manion, Yongqun He</obo:IAO_0000117>
        <obo:IAO_0000119 xml:lang="en">WEB: http://www.irb.umich.edu/policies/consent/</obo:IAO_0000119>
        <obo:IAO_0000119 xml:lang="en">WEB: http://www.who.int/rpc/research_ethics/informed_consent/en/</obo:IAO_0000119>
        <obo:IAO_0000232 xml:lang="en">This class is under group discussion as of 03/26/2019.</obo:IAO_0000232>
        <rdfs:label xml:lang="en">informed consent form for human biospecimen collection</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000014 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000014">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000001"/>
        <obo:IAO_0000115 xml:lang="en">An informed consent form that is specifically for human blood sample collection.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Alla Karnovsky, Frank Manion, Yongqun He</obo:IAO_0000117>
        <rdfs:label xml:lang="en">informed consent form for human blood sample collection</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000015 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000015">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/ICO_0000001"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/ICO_0000222"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000001"/>
        <obo:IAO_0000115 xml:lang="en">An informed consent form that has been signed by at least one participant.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Yongqun He</obo:IAO_0000117>
        <obo:IAO_0000232 xml:lang="en">Note from J. Neil Otte (7.24.18): &apos;signed informed consent form&apos; is not a synonym nor subclass of &apos;complete informed consent form indicating consent&apos;. A signed informed consent form may bear the signature of a witness or doctor, but not yet be complete. Also, a complete informed consent form may need only have been stamped or witnessed by checking a box in an electronic form, and may not require a signature.</obo:IAO_0000232>
        <rdfs:label xml:lang="en">signed informed consent form</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000016 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000016">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000033"/>
        <obo:IAO_0000115 xml:lang="en">A directive information entity that specifies the scope of allowed research and is derived from a research protocol.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Alla Karnovsky, Frank Manion, Yongqun He</obo:IAO_0000117>
        <obo:IAO_0000232 xml:lang="en">This class is under group discussion as of 03/26/2019.</obo:IAO_0000232>
        <rdfs:label xml:lang="en">allowed research scope in informed consent form</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000017 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000017">
        <rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
        <obo:IAO_0000115 xml:lang="en">An informed consent form that has been signed by all participants.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Yongqun He</obo:IAO_0000117>
        <rdfs:label>obsolete fully signed informed consent form</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000018 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000018">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000001"/>
        <obo:IAO_0000115 xml:lang="en">An informed consent form that has been signed by a human subject</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Yongqun He</obo:IAO_0000117>
        <obo:IAO_0000232 xml:lang="en">This class is under group discussion as of 03/26/2019.</obo:IAO_0000232>
        <rdfs:label xml:lang="en">informed consent form signed by human subject</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000019 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000019">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000314"/>
        <obo:IAO_0000115 xml:lang="en">A document part that is specified as a place to receive a signature.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Yongqun He</obo:IAO_0000117>
        <obo:IAO_0000232 xml:lang="en">This class is under group discussion as of 03/26/2019.</obo:IAO_0000232>
        <rdfs:label xml:lang="en">signature section</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000020 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000020">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000019"/>
        <obo:IAO_0000115 xml:lang="en">A signature section in informed consent element that that is specified as a place to receive a signature from a human subject.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Yongqun He</obo:IAO_0000117>
        <obo:IAO_0000232 xml:lang="en">This class is under group discussion as of 03/26/2019.</obo:IAO_0000232>
        <rdfs:label xml:lang="en">human subject signature section in informed consent form</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000021 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000021">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000019"/>
        <obo:IAO_0000115 xml:lang="en">A signature section in an informed consent form that is specified as a place to receive a signature from an investigator.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Yongqun He</obo:IAO_0000117>
        <obo:IAO_0000232 xml:lang="en">This class is under group discussion as of 03/26/2019.</obo:IAO_0000232>
        <rdfs:label xml:lang="en">investigator signature section in informed consent form</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000022 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000022">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000030"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000219"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/BFO_0000008"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <obo:IAO_0000115 xml:lang="en">A information content entity that designates a temporal region.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Alla Karnovsky, Frank Manion, Yongqun He, J. Neil Otte</obo:IAO_0000117>
        <obo:IAO_0000233>https://github.com/ICO-ontology/ICO/issues/36</obo:IAO_0000233>
        <rdfs:label xml:lang="en">temporal region identifier</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000023 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000023">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000001"/>
        <obo:IAO_0000115 xml:lang="en">An informed consent form that has been filled with all required contents.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Yongqun He</obo:IAO_0000117>
        <rdfs:label xml:lang="en">completely filled informed consent form</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000024 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000024">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000001"/>
        <obo:IAO_0000115 xml:lang="en">An informed consent form that has been partially filled with required contents.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Yongqun He</obo:IAO_0000117>
        <rdfs:label xml:lang="en">partially filled informed consent form</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000025 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000025">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000022"/>
        <obo:IAO_0000115 xml:lang="en">A date specification in an informed consent form that specifies an effective date of an investigation.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Alla Karnovsky, Frank Manion, Yongqun He</obo:IAO_0000117>
        <obo:IAO_0000232 xml:lang="en">This class is under group discussion as of 03/26/2019.</obo:IAO_0000232>
        <rdfs:label xml:lang="en">effective date specification in informed consent form</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000026 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000026">
        <rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
        <obo:IAO_0000115 xml:lang="en">A date specification in an informed consent form that specifies the expiration date of an investigation.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Alla Karnovsky, Frank Manion, Yongqun He</obo:IAO_0000117>
        <rdfs:label>obsolete expiration date specification in informed consent form</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000027 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000027">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000022"/>
        <obo:IAO_0000115 xml:lang="en">A date specification in an informed consent form that specifies the starting date of an investigation.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Yongqun He</obo:IAO_0000117>
        <obo:IAO_0000232 xml:lang="en">This class is under group discussion as of 03/26/2019.</obo:IAO_0000232>
        <rdfs:label xml:lang="en">starting date specification in informed consent form</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000028 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000028">
        <rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
        <obo:IAO_0000115 xml:lang="en">A document part that describes and specifies human blood sample collection procedures.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Yongqun He</obo:IAO_0000117>
        <rdfs:label>obsolete human blood sample collection section</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000029 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000029">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000001"/>
        <obo:IAO_0000115 xml:lang="en">An informed consent form that is used for a clinical study.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Yongqun He</obo:IAO_0000117>
        <obo:IAO_0000119 xml:lang="en">WEB: http://www.who.int/rpc/research_ethics/informed_consent/en/</obo:IAO_0000119>
        <obo:IAO_0000232 xml:lang="en">This class is under group discussion as of 03/26/2019.</obo:IAO_0000232>
        <rdfs:label xml:lang="en">informed consent form for clinical study</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000030 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000030">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000001"/>
        <obo:IAO_0000115 xml:lang="en">An informed consent form that is used for a storage and future use of unused samples.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Yongqun He</obo:IAO_0000117>
        <obo:IAO_0000119 xml:lang="en">WEB: http://www.who.int/rpc/research_ethics/informed_consent/en/</obo:IAO_0000119>
        <obo:IAO_0000232 xml:lang="en">This class is under group discussion as of 03/26/2019.</obo:IAO_0000232>
        <rdfs:label xml:lang="en">informed consent form for storage and future use of unused samples</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000031 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000031">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000001"/>
        <obo:IAO_0000115 xml:lang="en">An informed consent form that is used for a qualitative study.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Yongqun He</obo:IAO_0000117>
        <obo:IAO_0000119 xml:lang="en">WEB: http://www.who.int/rpc/research_ethics/informed_consent/en/</obo:IAO_0000119>
        <obo:IAO_0000232 xml:lang="en">This class is under group discussion as of 03/26/2019.</obo:IAO_0000232>
        <rdfs:label xml:lang="en">informed consent form for qualitative study</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000032 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000032">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000085"/>
        <obo:IAO_0000115 xml:lang="en">An informed consent form that is adapted to the cognitive abilities and reading abilities child or minor.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Yongqun He, Jonathan Vajda</obo:IAO_0000117>
        <obo:IAO_0000119 xml:lang="en">WEB: http://www.who.int/rpc/research_ethics/informed_consent/en/</obo:IAO_0000119>
        <rdfs:label xml:lang="en">informed assent form for child or minor</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000033 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000033">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000001"/>
        <obo:IAO_0000115 xml:lang="en">An informed consent form for qualitative study that involves children.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Yongqun He</obo:IAO_0000117>
        <obo:IAO_0000119 xml:lang="en">WEB: http://www.who.int/rpc/research_ethics/informed_consent/en/</obo:IAO_0000119>
        <rdfs:label xml:lang="en">informed consent form for qualitative research involving children</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000034 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000034">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000001"/>
        <obo:IAO_0000115 xml:lang="en">An informed consent form for clinical study that involves children.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Yongqun He</obo:IAO_0000117>
        <obo:IAO_0000119 xml:lang="en">WEB: http://www.who.int/rpc/research_ethics/informed_consent/en/</obo:IAO_0000119>
        <rdfs:label xml:lang="en">informed consent form for clinical research involving children</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000035 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000035">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000027"/>
        <obo:IAO_0000115 xml:lang="en">A data item that indicates a date that specified on an informed consent form.</obo:IAO_0000115>
        <obo:IAO_0000116 xml:lang="en">5/7/2014 Asiyah Yu Lin: It is the date specification that appears on the informed consent form, which is may different with the actual date.</obo:IAO_0000116>
        <obo:IAO_0000117 xml:lang="en">Yongqun He, Asiyah Yu Lin, J. Neil Otte</obo:IAO_0000117>
        <obo:IAO_0000232 xml:lang="en">This class is under group discussion as of 03/26/2019.</obo:IAO_0000232>
        <rdfs:label xml:lang="en">date specification in informed consent form</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000036 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000036">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000022"/>
        <obo:IAO_0000115 xml:lang="en">A date specification that designates when an informed consent form was signed.</obo:IAO_0000115>
        <obo:IAO_0000116 xml:lang="en">5/7/2014 Asiyah Yu Lin: look at the OBI example of sample collection date http://purl.obolibrary.org/obo/OBI_0001619</obo:IAO_0000116>
        <obo:IAO_0000117 xml:lang="en">Yongqun He, J. Neil Otte</obo:IAO_0000117>
        <rdfs:label>informed consent form signing date</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000037 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000037">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000022"/>
        <obo:IAO_0000115 xml:lang="en">A temporal region identifier that designates a project duration.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Yongqun He, J. Neil Otte</obo:IAO_0000117>
        <rdfs:label>project duration specification</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000038 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000038">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000022"/>
        <obo:IAO_0000115 xml:lang="en">A date specification that designates the date when a project begins.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">J. Neil Otte</obo:IAO_0000117>
        <rdfs:label xml:lang="en">project starting date specification</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000039 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000039">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000022"/>
        <obo:IAO_0000115 xml:lang="en">A date specification that designates the date when a project ends.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">J. Neil Otte</obo:IAO_0000117>
        <rdfs:label xml:lang="en">project end date specification</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000040 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000040">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:IAO_0000115 xml:lang="en">A human subject who provides informed consent without a legal guardian.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Yongqun He</obo:IAO_0000117>
        <obo:IAO_0000232 xml:lang="en">This class is under group discussion as of 03/26/2019.</obo:IAO_0000232>
        <rdfs:label xml:lang="en">human subject consenter</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000041 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000041">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000033"/>
        <obo:IAO_0000115 xml:lang="en">A directive information entity that specifies the deontic roles that are produced, revoked, or modified following a process of informed consent, where those deontic roles inhere in the human subject consenter signing an informed consent form, and the investigator or organization leading a research study or providing health care.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Yongqun He</obo:IAO_0000117>
        <obo:IAO_0000232 xml:lang="en">This class is under group discussion as of 03/26/2019.</obo:IAO_0000232>
        <rdfs:label xml:lang="en">informed consent rule specification</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000042 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000042">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000041"/>
        <obo:IAO_0000112 xml:lang="en">An example is that the organization leading a study may be obliged to destroy a patient&apos;s biospecimens after 10 years as required in an informed consent form.</obo:IAO_0000112>
        <obo:IAO_0000115 xml:lang="en">An informed consent rule specification that specifies a course of action legally required to be taken.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Yongqun He</obo:IAO_0000117>
        <obo:IAO_0000232 xml:lang="en">This class is under group discussion as of 03/26/2019.</obo:IAO_0000232>
        <rdfs:label xml:lang="en">obligation informed consent rule specification</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000043 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000043">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000041"/>
        <obo:IAO_0000115 xml:lang="en">An informed consent rule specification that specifies an optional course of action that is an option for a participant to take.</obo:IAO_0000115>
        <obo:IAO_0000116 xml:lang="en">An example is that a human subject consenter is given the option to withdraw from a consented study any time as specified in an informed consent form.</obo:IAO_0000116>
        <obo:IAO_0000117 xml:lang="en">Yongqun He</obo:IAO_0000117>
        <obo:IAO_0000232 xml:lang="en">This class is under group discussion as of 03/26/2019.</obo:IAO_0000232>
        <rdfs:label xml:lang="en">permission informed consent rule specification</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000044 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000044">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000027"/>
        <obo:IAO_0000115 xml:lang="en">A data item consisting of a unique identification code designating an informed consent.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Yongqun He</obo:IAO_0000117>
        <rdfs:label xml:lang="en">informed consent identification code</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000045 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000045">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
        <obo:IAO_0000115 xml:lang="en">A role borne by an agent that, if realized, is realized in an investigation.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">J. Neil Otte</obo:IAO_0000117>
        <rdfs:label xml:lang="en">investigator role</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000046 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000046">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0021003"/>
        <obo:IAO_0000115 xml:lang="en">A planned process of making the decision of the competent authorities in form of a letter, document, or verbal or electronic form, that confirms that somebody has permission to do something or be somewhere, e.g. to realize a given project.</obo:IAO_0000115>
        <obo:IAO_0000116 xml:lang="en">The alternative term of &apos;permission&apos; has semantic similarity with authorization in the sense of &apos;approval to do something&apos; and &apos;the act of giving a formal (usualy written) authorization. The semnatic similarity measuremment of permission and authorization is done using WordNet::Similarity (http://marimba.d.umn.edu/cgi-bin/similarity/)</obo:IAO_0000116>
        <obo:IAO_0000117 xml:lang="en">Asiyah Yu Lin, Yongqun He, Elizabeth Umberfield</obo:IAO_0000117>
        <obo:IAO_0000118 xml:lang="en">permission</obo:IAO_0000118>
        <obo:IAO_0000119 xml:lang="en">NCIt C41192</obo:IAO_0000119>
        <rdfs:label xml:lang="en">act of authorizing</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000047 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000047">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000181"/>
        <obo:IAO_0000115 xml:lang="en">A population of human beings.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Yongqun He</obo:IAO_0000117>
        <rdfs:label xml:lang="en">human population</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000048 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000048">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000245"/>
        <obo:IAO_0000115 xml:lang="en">An organization that is operated without the principal goal of making a financial profit.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Yongqun He</obo:IAO_0000117>
        <rdfs:label xml:lang="en">nonprofit organization</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000049 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000049">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000245"/>
        <obo:IAO_0000115 xml:lang="en">An organization which has the principle goal of earning financial profit.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Yongqun He</obo:IAO_0000117>
        <rdfs:label xml:lang="en">profit organization</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000050 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000050">
        <rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
        <obo:IAO_0000115 xml:lang="en">An investigation that involves animal research.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Yongqun He</obo:IAO_0000117>
        <rdfs:label>obsolete animal research investigation</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000051 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000051">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000066"/>
        <obo:IAO_0000115 xml:lang="en">An investigation that targets cancer research.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Yongqun He</obo:IAO_0000117>
        <rdfs:label xml:lang="en">cancer research investigation</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000052 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000052">
        <rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
        <obo:IAO_0000115 xml:lang="en">A cancer research investigation that specifically targets metastatic melanoma research.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Yongqun He</obo:IAO_0000117>
        <rdfs:label>obsolete metastatic melanoma research investigation</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000053 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000053">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000066"/>
        <obo:IAO_0000115 xml:lang="en">An investigation that targets drug testing.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Yongqun He</obo:IAO_0000117>
        <rdfs:label xml:lang="en">drug testing investigation</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000054 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000054">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000066"/>
        <obo:IAO_0000115 xml:lang="en">An investigation that involves human research.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Yongqun He</obo:IAO_0000117>
        <rdfs:label xml:lang="en">human research investigation</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000055 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000055">
        <rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
        <obo:IAO_0000115 xml:lang="en">An investigation that has process part some genetic analysis.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Yongqun He</obo:IAO_0000117>
        <rdfs:label>obsolete genetic study</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000056 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000056">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000066"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/ICO_0000224"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/ICO_0000048"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <obo:IAO_0000115 xml:lang="en">An investigation that is conducted with a nonprofit purpose.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Yongqun He</obo:IAO_0000117>
        <rdfs:label xml:lang="en">nonprofit research investigation</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000057 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000057">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000066"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/ICO_0000224"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/ICO_0000049"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <obo:IAO_0000115 xml:lang="en">An investigation that is conducted with the purpose of earning a profit.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Yongqun He</obo:IAO_0000117>
        <rdfs:label xml:lang="en">for-profit research investigation</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000058 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000058">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000038"/>
        <obo:IAO_0000115 xml:lang="en">A one-dimensional temporal region to which an investigation stands in the occupies_temporal_region relation.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">J. Neil Otte</obo:IAO_0000117>
        <rdfs:label xml:lang="en">investigation period</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000059 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000059">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000033"/>
        <obo:IAO_0000115 xml:lang="en">A directive information entity prescribes an ethical requirement.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Yongqun He, Cooper Stansbury</obo:IAO_0000117>
        <rdfs:label xml:lang="en">ethics directive</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000060 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000060">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000227"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000057"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0100051"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <obo:IAO_0000115 xml:lang="en">A planned process that involves placing a specimen in some location in order to maintain possession of it.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">J. Neil Otte</obo:IAO_0000117>
        <rdfs:label xml:lang="en">act of storing a specimen</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000061 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000061">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000001"/>
        <obo:IAO_0000115 xml:lang="en">An informed consent form that is designed for use in genetic studies.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Asiyah Yu Lin, Marcy Harris, Alla Karnovsky, Yongqun He</obo:IAO_0000117>
        <obo:IAO_0000232 xml:lang="en">This class is under group discussion as of 03/26/2019.</obo:IAO_0000232>
        <rdfs:label xml:lang="en">informed consent form for genetic study</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000062 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000062">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:IAO_0000115 xml:lang="en">A human subject who is unable to give informed consent. In this case, another person is generally authorized to give consent on his behalf, e.g., parents or legal guardians of a child, though in this circumstance the child may be required to provide informed assent, and conservators for the mentally ill.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Yongqun He</obo:IAO_0000117>
        <obo:IAO_0000119 xml:lang="en">web: http://en.wikipedia.org/wiki/informed_consent</obo:IAO_0000119>
        <obo:IAO_0000232 xml:lang="en">This class is under group discussion as of 03/26/2019.</obo:IAO_0000232>
        <rdfs:label xml:lang="en">human subject unable to give informed consent</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000063 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000063">
        <rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
        <obo:IAO_0000117 xml:lang="en">Marcy Harris</obo:IAO_0000117>
        <rdfs:label>obsolete informed consent form for quantitative study</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000064 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000064">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000066"/>
        <obo:IAO_0000115 xml:lang="en">An investigation that requires an informed consent process.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Yongqun He</obo:IAO_0000117>
        <obo:IAO_0000232 xml:lang="en">This class is under group discussion as of 03/26/2019.</obo:IAO_0000232>
        <rdfs:label xml:lang="en">study requiring informed consent</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000065 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000065">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000066"/>
        <obo:IAO_0000115 xml:lang="en">A study that is a clinical trial that requires an informed consent process.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Elizabeth Eisenhauer, Yongqun He</obo:IAO_0000117>
        <obo:IAO_0000232>Based on NCI/PT, a clinical trial is a type of research study that tests how well new medical approaches work in people. These studies test new methods of screening, prevention, diagnosis, or treatment of a disease.</obo:IAO_0000232>
        <obo:IAO_0000232 xml:lang="en">Needs work. Best fit is to rely on SIO_0001000, which has a fine-grained hierarchy. Parent is &apos;intervention study&apos; (SIO_0000994) which is an investigation (SIO_0000747). However, we have investigation already defined in OBI_0000066.</obo:IAO_0000232>
        <rdfs:label xml:lang="en">clinical trial</rdfs:label>
        <rdfs:seeAlso xml:lang="en">UMLS: C0008976</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000066 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000066">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001622"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000219"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/ICO_0000065"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <obo:IAO_0000115 xml:lang="en">An investigation title that designates a clinical trial study, briefly identifying the purpose or design of the investigation.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Elizabeth Eisenhauer, Yongqun He</obo:IAO_0000117>
        <obo:IAO_0000233>https://github.com/ICO-ontology/ICO/issues/36</obo:IAO_0000233>
        <rdfs:label xml:lang="en">clinical trial title</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000068 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000068">
        <rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
        <rdfs:label>obsolete general requirement for informed consent</rdfs:label>
        <rdfs:seeAlso xml:lang="en">§46.116 General requirements for informed consent</rdfs:seeAlso>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000069 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000069">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:IAO_0000115 xml:lang="en">A person who is the contact for questions about research.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Marcy Harris, Alla Karnovsky, Frank Manion, Asiyah Yu Lin, Elizabeth Eisenhauer, Yongqun He</obo:IAO_0000117>
        <obo:IAO_0000232 xml:lang="en">This class is under group discussion as of 03/26/2019.</obo:IAO_0000232>
        <rdfs:label xml:lang="en">contact person for questions about research</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000070 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000070">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:IAO_0000115 xml:lang="en">A person who is the contact for questions about research subject right.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Marcy Harris, Alla Karnovsky, Frank Manion, Asiyah Yu Lin, Elizabeth Eisenhauer, Yongqun He</obo:IAO_0000117>
        <obo:IAO_0000232 xml:lang="en">This class is under group discussion as of 03/26/2019.</obo:IAO_0000232>
        <rdfs:label xml:lang="en">contact person for questions about research subject rights</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000071 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000071">
        <rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
        <obo:IAO_0000115 xml:lang="en">A person who is the contact for questions in the event of a research-related injury to the subject</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Marcy Harris, Alla Karnovsky, Frank Manion, Asiyah Yu Lin, Elizabeth Eisenhauer, Yongqun He</obo:IAO_0000117>
        <rdfs:label>obsolete contact person in the event of a research-related injury to the subject</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000072 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000072">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:IAO_0000115 xml:lang="en">A person who can be contacted during an informed consent process.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Marcy Harris, Alla Karnovsky, Frank Manion, Asiyah Yu Lin, Elizabeth Eisenhauer, Yongqun He</obo:IAO_0000117>
        <obo:IAO_0000232 xml:lang="en">This class is under group discussion as of 03/26/2019.</obo:IAO_0000232>
        <rdfs:label xml:lang="en">contact person in informed consent process</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000073 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000073">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
        <obo:IAO_0000115 xml:lang="en">A role that inheres in human being and is an output of some participation in a research study.</obo:IAO_0000115>
        <obo:IAO_0000116 xml:lang="en">The term definition is adapted from the definition of the NCIt term &apos;Human Study Subject&apos; with modification.</obo:IAO_0000116>
        <obo:IAO_0000117 xml:lang="en">Yongqun He, Elizabeth Eisenhauer, Asiyah Yu Lin, Asiyah Yu Lin, Marcy Harris</obo:IAO_0000117>
        <obo:IAO_0000118 xml:lang="en">human patient</obo:IAO_0000118>
        <obo:ICO_0000091 xml:lang="en">C2349001</obo:ICO_0000091>
        <obo:ICO_0000092 xml:lang="en">C70665</obo:ICO_0000092>
        <rdfs:label xml:lang="en">research subject role</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000074 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000074">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000046"/>
        <obo:IAO_0000115 xml:lang="en">An act of authorizing that is signed by a patient, or his legal representative, or clinical study participant for the use or disclosure of oral, written, or electronic form of confidential health information that identifies the individual and relates to the medical history, diagnosis, treatment, or prognosis of his condition.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Asiyah Yu Lin, Yongqun He</obo:IAO_0000117>
        <obo:IAO_0000119 xml:lang="en">NCIt C70679</obo:IAO_0000119>
        <obo:IAO_0000232 xml:lang="en">This class is under group discussion as of 03/26/2019.</obo:IAO_0000232>
        <rdfs:label xml:lang="en">authorization for release of confidential health information</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000075 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000075">
        <rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
        <obo:IAO_0000115 xml:lang="en">A document that is the output of an authorization process.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000232 xml:lang="en">JV: This probably belongs in D-Acts</obo:IAO_0000232>
        <rdfs:label>obsolete authorization document</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000076 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000076">
        <rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
        <obo:IAO_0000115 xml:lang="en">An authorization process aims to release the medical record.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Asiyah Yu Lin</obo:IAO_0000117>
        <rdfs:label>obsolete authorization for medical records release</rdfs:label>
        <rdfs:seeAlso xml:lang="en">UMLS CUI: C2921556</rdfs:seeAlso>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000077 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000077">
        <rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
        <obo:IAO_0000115 xml:lang="en">A benefit is a disposition or the potential positive effects that may arise from participating in a study.</obo:IAO_0000115>
        <obo:IAO_0000116 xml:lang="en">This term definition is adopted from the NCIt definiton of &quot;benefit&quot; (C25387) with modification.</obo:IAO_0000116>
        <obo:IAO_0000117 xml:lang="en">Asiyah Yu Lin, Marcy Harris, Yongqun He, Elizabeth Eisenhauer, Alla Karnovsky, Frank Manion, J. Neil Otte, Cooper Stansbury</obo:IAO_0000117>
        <obo:ICO_0000091 xml:lang="en">C0814225</obo:ICO_0000091>
        <obo:ICO_0000092 xml:lang="en">C25387</obo:ICO_0000092>
        <rdfs:comment xml:lang="en">Note that a payment is not a benefit of a study.</rdfs:comment>
        <rdfs:label>obsolete benefit</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000078 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000078">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000016"/>
        <obo:IAO_0000115 xml:lang="en">A risk is a disposition or the potential future harm that may arise from some present action. It is often combined or confused with the probability of an event which is seen as undesirable.</obo:IAO_0000115>
        <obo:IAO_0000116 xml:lang="en">This term definition is adapted from the NCIt definiton of &quot;Risk&quot; (C17102) . The following source is alos referenced: BMEO(Biomedical Ethics Ontology) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2725426/</obo:IAO_0000116>
        <obo:IAO_0000117 xml:lang="en">Asiyah Yu Lin, Marcy Harris, Yongqun He, Elizabeth Eisenhauer, Alla Karnovsky, Frank Manion</obo:IAO_0000117>
        <obo:IAO_0000119 xml:lang="en">NCIt: C17102</obo:IAO_0000119>
        <obo:IAO_0000232 xml:lang="en">This class is under group discussion as of 03/26/2019.</obo:IAO_0000232>
        <obo:ICO_0000091 xml:lang="en">C0035647</obo:ICO_0000091>
        <obo:ICO_0000092 xml:lang="en">C17102</obo:ICO_0000092>
        <rdfs:label xml:lang="en">risk</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000079 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000079">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000245"/>
        <obo:IAO_0000115 xml:lang="en">A specially constituted organization comprised of medical, scientific and non-scientific members established and designated by an entity to ensure the protection of the rights, safety and well-being of human subjects recruited to participate in biomedical or behavioral research according to the requirements outlined in Title 38, part 16 (same as Title 45, part 46 and Title 21, part 56) of the U.S. Code of Federal Regulations. IRB responsibility include but not limited to the reviewing, approving, and providing continuing review of trial protocol and amendments and of the methods and material to be used in obtaining and documenting informed consent of the trial. Other equivalent committees with the same or similar functions are also considered to be IRBs.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000118 xml:lang="en">IRB</obo:IAO_0000118>
        <obo:IAO_0000119 xml:lang="en">NCIT C16741</obo:IAO_0000119>
        <obo:ICO_0000091 xml:lang="en">C0086911</obo:ICO_0000091>
        <rdfs:label xml:lang="en">institutional review board</rdfs:label>
        <rdfs:seeAlso rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&amp;code=C16741&amp;ns=NCI_Thesaurus</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000080 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000080">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
        <obo:IAO_0000115 xml:lang="en">a role inhering in a homo sapiens that, if realized, is realized in assisting with a research process.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Asiyah Yu Lin, J. Neil Otte</obo:IAO_0000117>
        <rdfs:label>research assistant role</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000081 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000081">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
        <obo:IAO_0000115 xml:lang="en">A role that inheres in an individual who is authorized under applicable State or local law to consent on behalf of a child or incapable person to general medical care including participation in clinical research.</obo:IAO_0000115>
        <obo:IAO_0000116 xml:lang="en">Yongqun He: Based on the definition, may be better to label it as consent legal guardian role</obo:IAO_0000116>
        <obo:IAO_0000117 xml:lang="en">Asiyah Yu Lin, Yongqun He</obo:IAO_0000117>
        <obo:IAO_0000118 xml:lang="en">legally authorized representative role</obo:IAO_0000118>
        <obo:IAO_0000119 xml:lang="en">NCTI C51828</obo:IAO_0000119>
        <obo:IAO_0000232 xml:lang="en">This class is under group discussion as of 03/26/2019.</obo:IAO_0000232>
        <rdfs:label xml:lang="en">legal guardian role</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000082 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000082">
        <rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
        <obo:IAO_0000116 xml:lang="en">Yongqun He: Based on the definition of &apos;legal guardian role&apos;, it may be better to label the term as &apos;consent legal guardian&apos; of &apos;legal guardian of consent&apos;.</obo:IAO_0000116>
        <obo:IAO_0000117 xml:lang="en">Asiyah Yu Lin, Yongqun He</obo:IAO_0000117>
        <obo:IAO_0000118 xml:lang="en">legally authorized representative</obo:IAO_0000118>
        <rdfs:label>obsolete legal guardian</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000083 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000083">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000103"/>
        <obo:IAO_0000115 xml:lang="en">A protected health information entity which identifies an individual; or with respect to which there is a reasonable basis to believe the information can be used to identify an individual.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Jonathan Vajda, J. Neil Otte</obo:IAO_0000117>
        <obo:IAO_0000232 xml:lang="en">Individually identifiable health information includes many common identifiers such as name, address, birth date, Social Security Number.</obo:IAO_0000232>
        <obo:IAO_0000232 xml:lang="en">This is adapted from HIPAA.</obo:IAO_0000232>
        <rdfs:label xml:lang="en">individually identifiable health information entity</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000084 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000084">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000810"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/ICO_0000197"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000810"/>
        <obo:IAO_0000115 xml:lang="en">An informed consent process that has an act of communicating assent as a process part, where the person who provides the assent does not bear a competency to consent.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Asiyah Yu Lin, Yongqun He, Frank Manion, Chris Stoeckert, Jihad Obeid, Jonathan Bona, Mathias Brochhausen</obo:IAO_0000117>
        <obo:IAO_0000117 xml:lang="en">J. Neil Otte, Jonathan Vajda</obo:IAO_0000117>
        <obo:IAO_0000119 xml:lang="en">http://www.hopkinsmedicine.org/institutional_review_board/guidelines_policies/guidelines/informed_consent_i.html</obo:IAO_0000119>
        <obo:IAO_0000119 xml:lang="en">https://www.cancer.gov/about-cancer/treatment/clinical-trials/patient-safety/childrens-assent</obo:IAO_0000119>
        <rdfs:label xml:lang="en">informed consent process with assent</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000085 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000085">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000310"/>
        <obo:IAO_0000115 xml:lang="en">A document that explains relevant information regarding the expectations and requirements of participation in a research study or clinical procedure, is adapted to the cognitive capacities of that individual so as to assist in that individual&apos;s understanding, and is designed to record the assent of that individual.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Yongqun He, Jonathan Vajda</obo:IAO_0000117>
        <rdfs:label xml:lang="en">informed assent form</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000086 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000086">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
        <obo:IAO_0000115 xml:lang="en">A role that inheres in a patient or the legal guadian when he/she participates the consenting process.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Asiyah Yu Lin, Yongqun He</obo:IAO_0000117>
        <obo:IAO_0000232 xml:lang="en">This class is under group discussion as of 03/26/2019.</obo:IAO_0000232>
        <rdfs:label xml:lang="en">consenter role</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000087 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000087">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000109"/>
        <obo:IAO_0000115 xml:lang="en">A time measurement datum that measures the duration of a study.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">J. Neil Otte</obo:IAO_0000117>
        <rdfs:label xml:lang="en">study duration measurement</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000088 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000088">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000038"/>
        <obo:IAO_0000115 xml:lang="en">A temporal interval during which a human being participates in a process.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">J. Neil Otte</obo:IAO_0000117>
        <rdfs:label xml:lang="en">participation duration</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000089 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000089">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000008"/>
        <obo:IAO_0000115 xml:lang="en">Total length of time of subject&apos;s participation in a clinical study; from the time of enrollment to the completion of follow-up.</obo:IAO_0000115>
        <obo:IAO_0000116 xml:lang="en">This duration is different with the &apos;planned duration of study subject participation&apos;</obo:IAO_0000116>
        <obo:IAO_0000117 xml:lang="en">Asiyah Yu Lin, Yongqun He</obo:IAO_0000117>
        <obo:IAO_0000232 xml:lang="en">This class is under group discussion as of 03/26/2019.</obo:IAO_0000232>
        <rdfs:label xml:lang="en">actual duration of study subject participation</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000090 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000090">
        <rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
        <obo:IAO_0000115 xml:lang="en">A document that certifies that 1) a person may perform some action, or 2) which provides authentication for a claim, or 3) which confirms position or status.</obo:IAO_0000115>
        <obo:IAO_0000116 xml:lang="en">5/8/2014 Asiyah Yu Lin: May not included in the final ontology.</obo:IAO_0000116>
        <rdfs:label>obsolete credential letter</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000094 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000094">
        <rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
        <obo:IAO_0000115 xml:lang="en">The process by which information about the health status of an individual is obtained after a study has officially closed; an activity that continues something that has already begun or that repeats something that has already been done.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119 xml:lang="en">NCIT:C16033</obo:IAO_0000119>
        <obo:IAO_0000232 xml:lang="en">Elizabeth: Pay attention to definition &quot;after study procedures and treatments have concluded.&quot; Does it fit our purposes?</obo:IAO_0000232>
        <obo:ICO_0000092 xml:lang="en">C16033</obo:ICO_0000092>
        <rdfs:label>obsolete follow-up visit</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000095 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000095">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000078"/>
        <obo:IAO_0000115 xml:lang="en">A risk that is equal or lesser than those ordinarily encountered in daily life or during the performance of routine physical or psychological examinations or tests.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Asiyah Yu Lin, Yongqun He</obo:IAO_0000117>
        <obo:IAO_0000119 xml:lang="en">(45 CFR 46.102(i)).  Available online from: http://www.hhs.gov/ohrp/humansubjects/guidance/45cfr46.html#46.102 Accessed 7/31/13.</obo:IAO_0000119>
        <obo:IAO_0000232 xml:lang="en">Definition varies slightly for research on prisoners; see (45 CFR 46.303(d)).</obo:IAO_0000232>
        <obo:IAO_0000232 xml:lang="en">This class is under group discussion as of 03/26/2019.</obo:IAO_0000232>
        <rdfs:label xml:lang="en">minimal risk</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000096 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000096">
        <rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
        <obo:IAO_0000115 xml:lang="en">A medical record that records the history of a subject&apos;s treatment for alcohol abuse.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Asiyah Yu Lin, Yongqun He</obo:IAO_0000117>
        <rdfs:label>obsolete alcohol abuse treatment record</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000097 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000097">
        <rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
        <obo:IAO_0000115 xml:lang="en">A medical record that describes a patient&apos;s mental health care history.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Asiyah Yu Lin</obo:IAO_0000117>
        <obo:ICO_0000091 xml:lang="en">C2114499</obo:ICO_0000091>
        <rdfs:label>obsolete mental health care record</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000098 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000098">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
        <obo:IAO_0000115 xml:lang="en">A planned process that involves explanation to a human subject candidate with relevant study information, including study purpose, protocol, and human subject benefits and risks, that indicated in an informed consent form.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Asiyah Yu Lin, Yongqun He</obo:IAO_0000117>
        <obo:IAO_0000232 xml:lang="en">This class is under group discussion as of 03/26/2019.</obo:IAO_0000232>
        <rdfs:label xml:lang="en">explaining to participant candidate about the study participating information</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000099 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000099">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000001"/>
        <obo:IAO_0000115 xml:lang="en">An informed consent form designed for use in human urine collection.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Alla Karnovsky, Frank Manion, Yongqun He</obo:IAO_0000117>
        <obo:IAO_0000232 xml:lang="en">This class is under group discussion as of 03/26/2019.</obo:IAO_0000232>
        <rdfs:label xml:lang="en">informed consent form for human urine biospecimen collection</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000100 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000100">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000102"/>
        <obo:IAO_0000115 xml:lang="en">A physical injury or illness that is a direct result of the treatment, or procedures required by the protocol, to which the subject would not have been exposed had they not participated in the study.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119 xml:lang="en">1) Citing Resnik, (2006), Mamotte N, Wassenaar D, Singh N (2013) define Research-related injury as “a physical, psychological, social, financial, or other injury, harm, or adverse event that a research participant experiences as a direct result of research participation or from use of the study product.”

2) Resnik, (2006)“A research-related injury is an injury that occurs to a subject as a result of research participation. Injuries may range from relatively minor harms (such as bruises or infected wounds) to major injuries (such as organ damage or temporary disability) to catastrophic injuries (such as permanent disability or death). An injury may require only acute or emergency care, or it may require continuing care. Injuries can be physical or psychological, or emotional.”p. 264</obo:IAO_0000119>
        <rdfs:label xml:lang="en">research-related injury</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000101 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000101">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000030"/>
        <obo:IAO_0000115 xml:lang="en">An information content entity which is created or received by a health care provider, health plan, public health authority, employer, life insurer, school or university, or health care clearinghouse; and relates to the past, present, or future physical or mental health or condition of any individual, the provision of health care to an individual, or the past, present, or future payment for the provision of health care to an individual.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Jonathan Vajda, J. Neil Otte</obo:IAO_0000117>
        <obo:IAO_0000232 xml:lang="en">This is adapted from HIPAA.</obo:IAO_0000232>
        <rdfs:label xml:lang="en">health information entity</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000102 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000102">
        <rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
        <obo:IAO_0000115 xml:lang="en">The process that shares the information under the informed consent context</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000232 xml:lang="en">The definition needs to be improved.</obo:IAO_0000232>
        <rdfs:label>obsolete information sharing process</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000103 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000103">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000101"/>
        <obo:IAO_0000115 xml:lang="en">A health information entity which is created, received, stored, or transmitted by covered entities and their business associates in relation to the provision of healthcare, healthcare operations and payment for healthcare services.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, J. Niel Otte, Jonathan Vadja</obo:IAO_0000117>
        <obo:IAO_0000232 xml:lang="en">This is adapted from HIPAA.</obo:IAO_0000232>
        <rdfs:label xml:lang="en">protected health information entity</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000104 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000104">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000001"/>
        <obo:IAO_0000115 xml:lang="en">An informed consent form that contains a questionnaire section.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Yongqun He</obo:IAO_0000117>
        <obo:IAO_0000232 xml:lang="en">This class is under group discussion as of 03/26/2019.</obo:IAO_0000232>
        <rdfs:label xml:lang="en">informed consent form containing questionnaire</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000105 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000105">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000154"/>
        <obo:IAO_0000115 xml:lang="en">As a partial process of inform the candidate about the study participating information, the purpose of the study will be explained to make sure that the candidate is informed adequately from his/her perspective.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Asiyah Yu Lin, Yongqun He</obo:IAO_0000117>
        <obo:IAO_0000232 xml:lang="en">This class is under group discussion as of 03/26/2019.</obo:IAO_0000232>
        <rdfs:label xml:lang="en">explaining study purpose to participant candidate</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000106 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000106">
        <rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
        <obo:IAO_0000115 xml:lang="en">Legal name is the person name that identifies a person for legal, administrative and other official purposes. A person&amp;apos;s first legal name generally is the name of the person that was given for the purpose of registration of the birth and which then appears on a birth certificate (see birth name), but may change subsequently.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119 xml:lang="en">http://en.wikipedia.org/wiki/Legal_name</obo:IAO_0000119>
        <rdfs:label>obsolete legal name</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000107 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000107">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000015"/>
        <obo:IAO_0000115 xml:lang="en">A process that terminates a study.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000232 xml:lang="en">Note from J. Neil Otte (7.24.18): This class is not to be confused with the terminal process boundary of a study process.</obo:IAO_0000232>
        <rdfs:label xml:lang="en">study termination</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000108 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000108">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
        <obo:IAO_0000115 xml:lang="en">A planned process in which an agent decides to discontinue further participation in a study.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Asiyah Yu Lin, J. Neil Otte</obo:IAO_0000117>
        <rdfs:label xml:lang="en">withdrawing participation in study</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000109 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000109">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
        <obo:IAO_0000115 xml:lang="en">A planned process that revokes a permission role inhering in some agent.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">J. Neil Otte</obo:IAO_0000117>
        <rdfs:label xml:lang="en">act of canceling a permission</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000110 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000110">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OGMS_0000090"/>
        <obo:IAO_0000115 xml:lang="en">A treatment currently in wide use and approved by a regulatory body or health authority, considered to be effective in the treatment of a specific disease or condition.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119 xml:lang="en">CDISC</obo:IAO_0000119>
        <rdfs:label xml:lang="en">standard medical treatment</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000111 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000111">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000028"/>
        <obo:IAO_0000115 xml:lang="en">A character string that is assigned by a review board upon approval of a regulatory document.</obo:IAO_0000115>
        <obo:IAO_0000116 xml:lang="en">For the review board approval, different countries or continents may have different responsible entities for approving the study. For example, in USA, the board is called &quot;Institutional Review Board&quot; (IRB). In many countries in Europe, it is called Ethics committee.</obo:IAO_0000116>
        <obo:IAO_0000116 xml:lang="en">This term definition is adapted from the definition of the NCIt term &apos;Review Board Approval Number Text&apos;.</obo:IAO_0000116>
        <obo:IAO_0000117 xml:lang="en">Asiyah Yu Lin, Elizabeth Eisenhauer, Yongqun He, Alla Karnovsky, Marcy Harris</obo:IAO_0000117>
        <obo:ICO_0000091 xml:lang="en">C2985863</obo:ICO_0000091>
        <obo:ICO_0000092 xml:lang="en">C93662</obo:ICO_0000092>
        <rdfs:label xml:lang="en">review board approval number</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000112 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000112">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000034"/>
        <obo:IAO_0000115 xml:lang="en">An organizational function that involves the areas of information systems and computer science; and that may be realized in planning, organizing, describing, and controlling data resources.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Asiyah Yu Lin, J. Neil Otte</obo:IAO_0000117>
        <obo:IAO_0000119 xml:lang="en">http://en.wikipedia.org/wiki/Data_administration</obo:IAO_0000119>
        <rdfs:label xml:lang="en">data administration function</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000113 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000113">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000030"/>
        <obo:IAO_0000115 xml:lang="en">An information content entity that has been processed to prevent the identification of the person with whom the data are associated, thereby enduring in a stasis of anonymization.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Jonathan Vajda, Asiyah Yu Lin</obo:IAO_0000117>
        <rdfs:comment xml:lang="en">Anonymized data is applicable particularly for secondary use of health data.</rdfs:comment>
        <rdfs:label xml:lang="en">anonymized information content entity</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000114 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000114">
        <rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
        <obo:IAO_0000115 xml:lang="en">An anonymized data item that is about a genomic sample.</obo:IAO_0000115>
        <obo:IAO_0000116 xml:lang="en">Anonymized data and samples are initially single or double coded but the link between the subjects identifiers and the unique code(s) are subsequently deleted. Once the link has been deleted it is no longer possible to trace the data and samples back to the individual through the coding key(s). Anonymisation is intended to prevent subject re-identification. As anonymised samples and associated data are not traceable back to the subject it is not possible to undertake actions such as sample withdrawal, or the return of individual results. The use of anonymised data and samples does not allow for clinical monitoring, subject follow-up or the addition of new data. The deletion of the coding key(s) linking the data and samples to the subjects identifiers provides additional confidentiality and privacy protection over coded data and samples, as it prevents subject re-identification through the use of the coding key(s) (ICH).</obo:IAO_0000116>
        <obo:IAO_0000117 xml:lang="en">Asiyah Yu Lin, Yongqun He, J. Neil Otte</obo:IAO_0000117>
        <rdfs:label>obsolete anonymized genomic data</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000115 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000115">
        <rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
        <obo:IAO_0000115 xml:lang="en">An anonymized information content entity about a genomic sample.</obo:IAO_0000115>
        <obo:IAO_0000116 xml:lang="en">Anonymized data and samples are initially single or double coded but the link between the subjects identifiers and the unique code is subsequently deleted. Once the link has been deleted it is no longer possible to trace the data and samples back to the individual through the coding key. Anonymisation is intended to prevent subject re-identification. As anonymised samples and associated data are not traceable back to the subject it is not possible to undertake actions such as sample withdrawal, or the return of individual results. The use of anonymised data and samples does not allow for clinical monitoring, subject follow-up or the addition of new data. The deletion of the coding key linking the data and samples to the subjects identifiers provides additional confidentiality and privacy protection over coded data and samples, as it prevents subject re-identification through the use of the coding key (ICH).</obo:IAO_0000116>
        <rdfs:label>obsolete anonymized genomic sample</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000116 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000116">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000421"/>
        <obo:IAO_0000115 xml:lang="en">A planned process that involves using data which was an output of a human being&apos;s participation in a study and which is about that human being.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">J. Neil Otte, Elizabeth Umberfield</obo:IAO_0000117>
        <rdfs:label xml:lang="en">act of using study participant data</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000117 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000117">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000154"/>
        <obo:IAO_0000115 xml:lang="en">In order to make sure that the candidate is informed adequately from his or her perspective, the protocol of the study including the protocol of participating, for example, what kind of procedure the participant will be involved, how many scheduled visits will be explained.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Asiyah Yu Lin, Yongqun He</obo:IAO_0000117>
        <obo:IAO_0000232 xml:lang="en">This class is under group discussion as of 03/26/2019.</obo:IAO_0000232>
        <rdfs:label xml:lang="en">explaining study protocol to participant candidate</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000118 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000118">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000029"/>
        <obo:IAO_0000115 xml:lang="en">A site where documents are preserved.</obo:IAO_0000115>
        <obo:IAO_0000116 xml:lang="en">This term is extracted from Nick&apos;s comment on the ICBO paper draft version0.11_Yongqun He.</obo:IAO_0000116>
        <obo:IAO_0000117 xml:lang="en">Asiyah Yu Lin</obo:IAO_0000117>
        <rdfs:label xml:lang="en">repository of documents</rdfs:label>
        <rdfs:seeAlso xml:lang="en">UMLS: C0003738</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000119 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000119">
        <rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
        <obo:IAO_0000116 xml:lang="en">This term is extracted from Nick&apos;s comment on the ICBO paper draft version0.11_Yongqun He.</obo:IAO_0000116>
        <obo:IAO_0000117 xml:lang="en">Asiyah Yu Lin</obo:IAO_0000117>
        <rdfs:label>obsolete storage duration of signed informed consent form</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000120 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000120">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
        <obo:IAO_0000115 xml:lang="en">A planned process that collect a signed  informed consent form. During this process, the information is systematically kept in a repository.</obo:IAO_0000115>
        <obo:IAO_0000116 xml:lang="en">We can put this axiom: inform... &apos;s located in&apos; some &apos;archive reposigtory of signed informed consent&apos;</obo:IAO_0000116>
        <obo:IAO_0000117 xml:lang="en">Marcy Harris, Alla Karnovsky, Asiyah Yu Lin, Elizabeth Eisenhauer, Yongqun He</obo:IAO_0000117>
        <obo:IAO_0000118 xml:lang="en">storage of signed informed consent form</obo:IAO_0000118>
        <obo:IAO_0000232 xml:lang="en">This class is under group discussion as of 03/26/2019.</obo:IAO_0000232>
        <rdfs:label xml:lang="en">archiving signed informed consent form</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000121 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000121">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000154"/>
        <obo:IAO_0000115 xml:lang="en">The potential benefit to the study subject that may arise from participating the study research is to be explained to candidate</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Yongqun He</obo:IAO_0000117>
        <obo:IAO_0000232 xml:lang="en">This class is under group discussion as of 03/26/2019.</obo:IAO_0000232>
        <rdfs:label xml:lang="en">explaining benefits of participation to participant candidate</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000122 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000122">
        <rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
        <obo:IAO_0000115 xml:lang="en">A directive information entity that specifies US federal policy for the protection of human subjects.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Elizabeth Eisenhauer, Marcy Harris, Alla Karnovsky, Yongqun He, Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000118 xml:lang="en">Common Rule</obo:IAO_0000118>
        <obo:IAO_0000119 xml:lang="en">WEB: http://www.hhs.gov/ohrp/humansubjects/commonrule/</obo:IAO_0000119>
        <rdfs:label>obsolete US federal policy for the protection of human subjects</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000123 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000123">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000227"/>
        <obo:IAO_0000115 xml:lang="en">An act of storing a complete informed consent form.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Yongqun He, Elizabeth Eisenhauer, Alla Karnovsky, Marcy Harris, J. Neil Otte</obo:IAO_0000117>
        <rdfs:comment xml:lang="en">Note: there were previously some related classes that distinguished the format of the informed consent form (e.g. electronic vs. paper). These distinctions are collapsed here. If making this distinction is necessary, the outputs of an instance of this class may be distinguished in their formatting. For instance, storing in an electronic format would entail an instance of an act of storing signed informed consent form bearing an &apos;has output&apos; relation to an instance of an informed consent form that is in an electronic format.</rdfs:comment>
        <rdfs:label>act of storing signed informed consent form</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000124 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000124">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
        <obo:IAO_0000115 xml:lang="en">A planned process of storage of signed informed consent form when the form is in digital format.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Marcy Harris, Alla Karnovsky, Elizabeth Eisenhauer, Yongqun He</obo:IAO_0000117>
        <obo:IAO_0000118 xml:lang="en">storage of signed electronic informed consent form</obo:IAO_0000118>
        <obo:IAO_0000232 xml:lang="en">This class is under group discussion as of 03/26/2019.</obo:IAO_0000232>
        <rdfs:label xml:lang="en">archiving signed electronic informed consent form</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000125 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000125">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000120"/>
        <obo:IAO_0000115 xml:lang="en">A process of storage of signed informed consent form when the form is in digital format.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Marcy Harris, Alla Karnovsky, Elizabeth Eisenhauer, Yongqun He</obo:IAO_0000117>
        <obo:IAO_0000118 xml:lang="en">storage of signed scanned paper informed consent form</obo:IAO_0000118>
        <obo:IAO_0000232 xml:lang="en">This class is under group discussion as of 03/26/2019.</obo:IAO_0000232>
        <rdfs:label xml:lang="en">archiving signed scanned paper informed consent form</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000126 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000126">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000008"/>
        <obo:IAO_0000115 xml:lang="en">A temporal interval that represents a period of time during which a signed informed consent form is stored.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Yongqun He, Elizabeth Eisenhauer, Asiyah Yu Lin, Alla Karnovsky, Marcy Harris</obo:IAO_0000117>
        <obo:IAO_0000119 xml:lang="en">WEB: http://answers.hhs.gov/ohrp/questions/7223</obo:IAO_0000119>
        <obo:IAO_0000232 xml:lang="en">This class is under group discussion as of 03/26/2019.</obo:IAO_0000232>
        <rdfs:label xml:lang="en">storage duration of signed informed consent form</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000127 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000127">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000104"/>
        <obo:IAO_0000115 xml:lang="en">A participation time that is the total length of time of subject&apos;s participation in a research study; from the time of enrollment to the completion of follow-up.</obo:IAO_0000115>
        <obo:IAO_0000116 xml:lang="en">The term definition is adapted from NCIt definition of &quot;Planned Duration of Study Subject Participation&quot; (C70707) with modification. Compared to the NCIt definition, the ICO definition specifies research research study instead of a clinical study.</obo:IAO_0000116>
        <obo:IAO_0000117 xml:lang="en">Asiyah Yu Lin, Yongqun He</obo:IAO_0000117>
        <obo:IAO_0000232 xml:lang="en">This class is under group discussion as of 03/26/2019.</obo:IAO_0000232>
        <obo:IAO_0000233>https://github.com/ICO-ontology/ICO/issues/35</obo:IAO_0000233>
        <obo:ICO_0000091 xml:lang="en">C2347527</obo:ICO_0000091>
        <obo:ICO_0000092 xml:lang="en">C70707</obo:ICO_0000092>
        <rdfs:label xml:lang="en">planned duration of study subject participation</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000128 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000128">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000154"/>
        <obo:IAO_0000115 xml:lang="en">The potential future harm that may arise from participating the study research is to be explained to candidate</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Asiyah Yu Lin, Yongqun He</obo:IAO_0000117>
        <obo:IAO_0000232 xml:lang="en">This class is under group discussion as of 03/26/2019.</obo:IAO_0000232>
        <rdfs:label xml:lang="en">explaining risks of participation to participant candidate</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000129 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000129">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000001"/>
        <obo:IAO_0000115 xml:lang="en">An informed consent form for human sample collection that is specifically for human saliva sample collection.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Alla Karnovsky, Frank Manion, Yongqun He, Elizabeth Eisenhauer, Marcy Harris, Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000119 xml:lang="en">WEB: http://www.irb.umich.edu/policies/consent/</obo:IAO_0000119>
        <obo:IAO_0000119 xml:lang="en">WEB: http://www.irb.umich.edu/policies/consent/samples/Sample_SalivaCollection.pdf</obo:IAO_0000119>
        <obo:IAO_0000232 xml:lang="en">This class is under group discussion as of 03/26/2019.</obo:IAO_0000232>
        <rdfs:label xml:lang="en">informed consent form for human saliva sample collection</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000131 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000131">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000111"/>
        <obo:IAO_0000115 xml:lang="en">A review board approval number that is assigned by an institutional review board.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Asiyah Yu Lin, Elizabeth Eisenhauer, Yongqun He, Alla Karnovsky, Marcy Harris</obo:IAO_0000117>
        <obo:IAO_0000118 xml:lang="en">institutional review board approval number</obo:IAO_0000118>
        <rdfs:label xml:lang="en">institutional review board approval number</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000133 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000133">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000154"/>
        <obo:IAO_0000115 xml:lang="en">In order to make sure that the candidate is informed adequately from his or her perspective, the process of collecting, storing or destroying the sample collected from the study subject is to be explained.</obo:IAO_0000115>
        <obo:IAO_0000116 xml:lang="en">In the case of biobanking,collected tissue will be frozen and stored in a biorepository system. Other researchers will search and use the tissue for different purpose. The researchers may come from different organization and may need to access some of the personal information or may need to contact the study subject.</obo:IAO_0000116>
        <obo:IAO_0000117 xml:lang="en">Asiyah Yu Lin, Yongqun He</obo:IAO_0000117>
        <obo:IAO_0000232 xml:lang="en">This class is under group discussion as of 03/26/2019.</obo:IAO_0000232>
        <rdfs:label xml:lang="en">explaining sample process and usage to participant candidate</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000134 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000134">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000154"/>
        <obo:IAO_0000115 xml:lang="en">In the case of promoting future data sharing, the usage of the data derived from a study is to be explained to the candidate.</obo:IAO_0000115>
        <obo:IAO_0000116 xml:lang="en">For example, in the genomic data projects, the study subject&apos;s sequence data maybe used outside of the original organization. In this case, the study subject&apos;s privacy need to be protected.</obo:IAO_0000116>
        <obo:IAO_0000117 xml:lang="en">Asiyah Yu Lin, Yongqun He</obo:IAO_0000117>
        <obo:IAO_0000232 xml:lang="en">This class is under group discussion as of 03/26/2019.</obo:IAO_0000232>
        <rdfs:label xml:lang="en">explaining study derived data usage to participant candidate</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000135 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000135">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000154"/>
        <obo:IAO_0000115 xml:lang="en">In order to enable the candidate to make voluntary decision, the options for enhancing the protection of confidentiality for participants who have contributed personal information to a study is to be explained.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Asiyah Yu Lin, Yongqun He</obo:IAO_0000117>
        <obo:IAO_0000119 xml:lang="en">http://www.qualitative-research.net/index.php/fqs/article/view/1024/2207.#g42</obo:IAO_0000119>
        <obo:IAO_0000232 xml:lang="en">This class is under group discussion as of 03/26/2019.</obo:IAO_0000232>
        <rdfs:label xml:lang="en">explaining record confidentiality to participant candidate</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000136 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000136">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000015"/>
        <obo:IAO_0000115 xml:lang="en">A process in which a candidate makes a voluntary decision to join a study, following their consideration of adequate information presented to them regarding the study and their participation in it.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Asiyah Yu Lin, Yongqun He</obo:IAO_0000117>
        <obo:IAO_0000119 xml:lang="en">https://depts.washington.edu/bioethx/topics/consent.html</obo:IAO_0000119>
        <obo:IAO_0000232 xml:lang="en">This class is under group discussion as of 03/26/2019.</obo:IAO_0000232>
        <rdfs:label xml:lang="en">participant candidate making voluntary decision of acceptance</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000137 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000137">
        <rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
        <obo:IAO_0000115 xml:lang="en">In order for the consent valid, the candidate should be competent to understand what has been explained.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Asiyah Yu Lin.</obo:IAO_0000117>
        <obo:IAO_0000119 xml:lang="en">https://depts.washington.edu/bioethx/topics/consent.html</obo:IAO_0000119>
        <rdfs:label>obsolete assessment of participant candidate understanding</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000138 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000138">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000001"/>
        <obo:IAO_0000115 xml:lang="en">An informed consent form that contains sections specific to procedures in vaccination.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Yongqun He, Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000118 xml:lang="en">immunization consent form</obo:IAO_0000118>
        <rdfs:label xml:lang="en">informed consent form for vaccination</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000139 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000139">
        <rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
        <obo:IAO_0000115 xml:lang="en">An informed consent form that is used for vaccination by Walgreens</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Yongqun He</obo:IAO_0000117>
        <obo:IAO_0000118>Walgreens Vaccine Administration Record Informed Concsent Form</obo:IAO_0000118>
        <rdfs:label>obsolete Walgreens vaccine informed consent form&apos;</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000140 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000140">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001000"/>
        <obo:IAO_0000115 xml:lang="en">A questionnaire whose purpose is to aid in identifying whether an agent is eligible to participate in a process.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">J. Neil Otte</obo:IAO_0000117>
        <rdfs:label xml:lang="en">eligibility questionnaire</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000141 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000141">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000300"/>
        <obo:IAO_0000115 xml:lang="en">A textual entity that is a sentence in the interrogative mood.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">J. Neil Otte</obo:IAO_0000117>
        <rdfs:label xml:lang="en">question textual entity</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000142 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000142">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
        <obo:IAO_0000115 xml:lang="en">A planned process that results in a legally effective consent status.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Frank Manion, Yongqun He</obo:IAO_0000117>
        <obo:IAO_0000232 xml:lang="en">This class is under group discussion as of 03/26/2019.</obo:IAO_0000232>
        <rdfs:label xml:lang="en">legally effective consenting</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000143 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000143">
        <rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
        <obo:IAO_0000115 xml:lang="en">A planned process of acknowledgement, or agreement, to participate in a procedure or study, where the participant is incapable of informed consent.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Asiyah Yu Lin, Yongqun He, Frank Manion, Chris Stoeckert, Jihad Obeid, Jonathan Bona, Mathias Brochhausen, 2018 Informed Consent Workshop</obo:IAO_0000117>
        <obo:IAO_0000118 xml:lang="en">assent process</obo:IAO_0000118>
        <obo:IAO_0000119 xml:lang="en">http://www.medtran.ru/eng/trials/protomechanics/ch3.htm</obo:IAO_0000119>
        <obo:IAO_0000119 xml:lang="en">https://www.cancer.gov/about-cancer/treatment/clinical-trials/patient-safety/childrens-assent</obo:IAO_0000119>
        <obo:IAO_0000119 xml:lang="en">https://www.hhs.gov/ohrp/regulations-and-policy/regulations/45-cfr-46/index.html#46.408</obo:IAO_0000119>
        <obo:IAO_0000119 xml:lang="en">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3777303/</obo:IAO_0000119>
        <rdfs:comment xml:lang="en">According to the Common Rule, the IRB shall determine that adequate provisions are made for soliciting the assent of the children, when in the judgment of the IRB the children are capable of providing assent.</rdfs:comment>
        <rdfs:comment xml:lang="en">Specifically, &quot;assent&quot; is a term used to express willingness to participate in research by persons who are by definition too young to give informed consent but who are old enough to understand the proposed research in general, its expected risks and possible benefits, and the activities expected of them as subjects.</rdfs:comment>
        <rdfs:label>obsolete assent process</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000144 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000144">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
        <obo:IAO_0000115 xml:lang="en">A role that inheres in a human being who participates in a consenting process and eventually becomes legally effectively consented.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Frank Manion, Yongqun He, Mathias Bronchhausen, Chris Stoeckert, Jie Zheng, Jihad Obeid, Helena Ellis</obo:IAO_0000117>
        <obo:IAO_0000232 xml:lang="en">This class is under group discussion as of 03/26/2019.</obo:IAO_0000232>
        <rdfs:label xml:lang="en">legally effective consented participant role</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000145 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000145">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
        <obo:IAO_0000115 xml:lang="en">A planned process in which an agent&apos;s designated biological specimen is collected after the death of the agent.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Yongqun He</obo:IAO_0000117>
        <rdfs:label xml:lang="en">postmortem donation of biological specimen</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000146 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000146">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
        <obo:IAO_0000115 xml:lang="en">A role that represents the eligibility of a candidate according to a study protocol.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Frank Manion, Yongqun He, Mathias Brochhausen, William Duncan</obo:IAO_0000117>
        <obo:IAO_0000232 xml:lang="en">This class is under group discussion as of 03/26/2019.</obo:IAO_0000232>
        <rdfs:label xml:lang="en">eligibility of candidate participation</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000147 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000147">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
        <obo:IAO_0000115 xml:lang="en">A role inhering in a participant who meets all eligibility criteria defined within a study protocol.</obo:IAO_0000115>
        <obo:IAO_0000119 xml:lang="en">NCI BBRB: Biorepositories and Biospecimen Research Branch</obo:IAO_0000119>
        <rdfs:label xml:lang="en">candidate eligible for study role</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000148 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000148">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
        <obo:IAO_0000115 xml:lang="en">A role inhering in a participant who does not meet all eligibility criteria defined within the study protocol.</obo:IAO_0000115>
        <obo:IAO_0000119 xml:lang="en">NCI BBRB: Biorepositories and Biospecimen Research Branch</obo:IAO_0000119>
        <rdfs:label xml:lang="en">candidate ineligible for study role</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000149 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000149">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
        <obo:IAO_0000115 xml:lang="en">A planned process in which an agent contacts a participant of an informed consent process regarding opportunities related to future research.</obo:IAO_0000115>
        <obo:IAO_0000117>Jonathan Vajda with ICO Workgroup in Ann Arbor (2018)</obo:IAO_0000117>
        <obo:IAO_0000117 xml:lang="en">Yongqun He, Mathias Brochhausen, Jihad Obeid, Frank Manion</obo:IAO_0000117>
        <obo:IAO_0000119 xml:lang="en">https://sbsirb.uchicago.edu/page/consent-form-templates-and-examples</obo:IAO_0000119>
        <rdfs:label xml:lang="en">act of contact for future research</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000150 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000150">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
        <obo:IAO_0000115 xml:lang="en">A planned process to screen the eligibility of a candidate for a study or procedure, verifying whether certain sufficient or necessary conditions for eligibility obtain.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Frank Manion, Yongqun He</obo:IAO_0000117>
        <rdfs:label xml:lang="en">eligibility screening process</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000151 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000151">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
        <obo:IAO_0000115 xml:lang="en">A role that inheres in a person that, if realized, is realized in an eligibility screening process.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Frank Manion, Yongqun He, J. Neil Otte</obo:IAO_0000117>
        <rdfs:label>eligibility screening role</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000152 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000152">
        <rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
        <obo:IAO_0000117 xml:lang="en">Frank Manion, Yongqun He</obo:IAO_0000117>
        <rdfs:label>obsolete eligibility screening person</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000153 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000153">
        <rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
        <rdfs:label>obsolete consenting to be contacted for tissue research</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000154 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000154">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
        <obo:IAO_0000115 xml:lang="en">A planned process of communicating information about an informed consent process.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Yongqun He, Cooper Stansbury</obo:IAO_0000117>
        <rdfs:label xml:lang="en">explaining to participant candidate in informed consent process</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000155 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000155">
        <rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
        <obo:IAO_0000115 xml:lang="en">A planned process that a person agrees to participate in a research project, which is a part of an informed consent process.</obo:IAO_0000115>
        <obo:IAO_0000115 xml:lang="en">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3777303/</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">YH, 2018 Little Rock CTSOG ontology workshop</obo:IAO_0000117>
        <rdfs:label>obsolete informed consent</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000156 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000156">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000810"/>
        <obo:IAO_0000115 xml:lang="en">An informed consent process where the person who is being asked to consent is an adult.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">J. Neil Otte</obo:IAO_0000117>
        <obo:IAO_0000119 xml:lang="en">https://oprs.usc.edu/files/2017/04/Informed-Consent-Booklet-4.4.13.pdf</obo:IAO_0000119>
        <obo:IAO_0000119 xml:lang="en">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3777303/</obo:IAO_0000119>
        <rdfs:label xml:lang="en">adult consent process</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000157 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000157">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000810"/>
        <obo:IAO_0000115 xml:lang="en">An informed consent process in which a parent reaches a decision concerning whether or not to grant consent on a minor&apos;s behalf, when the minor is incapable of providing consent for themselves.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">J. Neil Otte</obo:IAO_0000117>
        <obo:IAO_0000118 xml:lang="en">parental permission</obo:IAO_0000118>
        <obo:IAO_0000118 xml:lang="en">parental permission consent</obo:IAO_0000118>
        <obo:IAO_0000119 xml:lang="en">https://oprs.usc.edu/files/2017/04/Informed-Consent-Booklet-4.4.13.pdf</obo:IAO_0000119>
        <obo:IAO_0000119 xml:lang="en">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3777303/</obo:IAO_0000119>
        <rdfs:label xml:lang="en">parental informed consent process</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000158 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000158">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
        <obo:IAO_0000115 xml:lang="en">A planned process in which a person decides not to provide consent.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">J. Neil Otte</obo:IAO_0000117>
        <rdfs:label xml:lang="en">act of declining to provide consent</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000159 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000159">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000196"/>
        <obo:IAO_0000115 xml:lang="en">An informed consent process in which the participant communicates consent orally rather than by filling out and signing a written form.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Yongqun He, 2018 Little Rock CTSOG ontology workshop</obo:IAO_0000117>
        <obo:IAO_0000119 xml:lang="en">https://oprs.usc.edu/files/2017/04/Informed-Consent-Booklet-4.4.13.pdf</obo:IAO_0000119>
        <obo:IAO_0000119 xml:lang="en">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3777303/</obo:IAO_0000119>
        <rdfs:label xml:lang="en">informed verbal consent</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000160 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000160">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000810"/>
        <obo:IAO_0000115 xml:lang="en">An informed consent process in which the participant is not able to read and write in the language of the informed consent form, but is aided in understanding the informed consent process by a translation into the agent&apos;s native language.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">J. Neil Otte</obo:IAO_0000117>
        <obo:IAO_0000119 xml:lang="en">https://oprs.usc.edu/files/2017/04/Informed-Consent-Booklet-4.4.13.pdf</obo:IAO_0000119>
        <obo:IAO_0000119 xml:lang="en">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3777303/</obo:IAO_0000119>
        <rdfs:label xml:lang="en">consenting in short form</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000161 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000161">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
        <obo:IAO_0000115 xml:lang="en">A planned process in which a biological sample from a subject is collected for testing.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Yongqun He</obo:IAO_0000117>
        <obo:IAO_0000119 xml:lang="en">https://www.ncbi.nlm.nih.gov/books/NBK110047/</obo:IAO_0000119>
        <rdfs:label xml:lang="en">biological sample collecting</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000162 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000162">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000161"/>
        <obo:IAO_0000115 xml:lang="en">A biological sample collecting in which a tissue sample from a subject is collected for testing.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Yongqun He</obo:IAO_0000117>
        <obo:IAO_0000119 xml:lang="en">https://www.ncbi.nlm.nih.gov/books/NBK110047/</obo:IAO_0000119>
        <rdfs:label xml:lang="en">tissue sample collecting</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000163 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000163">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000161"/>
        <obo:IAO_0000115 xml:lang="en">A biological sample collecting in which a blood sample from a subject is collected for testing.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Yongqun He</obo:IAO_0000117>
        <obo:IAO_0000119 xml:lang="en">https://www.ncbi.nlm.nih.gov/books/NBK110047/</obo:IAO_0000119>
        <rdfs:label xml:lang="en">blood sample collecting</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000164 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000164">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
        <obo:IAO_0000115 xml:lang="en">A planned process that represents a study participant withdrawing from the study and agreeing to have the participant sample stored for unlimited time.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">2018 CTSOG informed consent ontology workshop in Little Rock (http://ncorwiki.buffalo.edu/index.php/Ontology_of_Informed_Consent:_An_Approach_to_Specimen_and_Data_Sharing)</obo:IAO_0000117>
        <obo:IAO_0000117 xml:lang="en">Yongqun He</obo:IAO_0000117>
        <obo:IAO_0000232 xml:lang="en">This class is under group discussion as of 03/26/2019.</obo:IAO_0000232>
        <rdfs:label xml:lang="en">subject withdrawal with sample stored for unlimited time</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000165 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000165">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
        <obo:IAO_0000115 xml:lang="en">A planned process that represents a study participant withdrawing from the study and agreeing to have the participant sample stored for a limited time period.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">2018 CTSOG informed consent ontology workshop in Little Rock (http://ncorwiki.buffalo.edu/index.php/Ontology_of_Informed_Consent:_An_Approach_to_Specimen_and_Data_Sharing)</obo:IAO_0000117>
        <obo:IAO_0000117 xml:lang="en">Yongqun He</obo:IAO_0000117>
        <obo:IAO_0000232 xml:lang="en">This class is under group discussion as of 03/26/2019.</obo:IAO_0000232>
        <rdfs:label xml:lang="en">subject withdrawal with sample stored for limited time</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000166 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000166">
        <rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
        <obo:IAO_0000232 xml:lang="en">Moved to d-acts</obo:IAO_0000232>
        <rdfs:label>obsolete deontic role</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000167 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000167">
        <rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
        <obo:IAO_0000115 xml:lang="en">A deontic role that if realized is realized by its bearer conducting or overseeing genetic research on the genome of a human donor.</obo:IAO_0000115>
        <rdfs:comment xml:lang="en">Note: this term wll be transferred to d-acts. - CTSOG ontology workshop 2018 Little Rock</rdfs:comment>
        <rdfs:label>obsolete permittee deontic role in genetic research</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000168 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000168">
        <rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
        <obo:IAO_0000115 xml:lang="en">A deontic declaration that has output a permittee role that permits genetic research on a human donor as a specified outcome.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Jonathan Vajda</obo:IAO_0000117>
        <rdfs:comment xml:lang="en">will add an equivalent class axiom
&apos;has specified output&apos; some &apos;permittee deontic role in genetic research&apos;</rdfs:comment>
        <rdfs:label>obsolete genetic research permission deontic declaration</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000169 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000169">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
        <obo:IAO_0000115 xml:lang="en">a role that inheres in a human subject who participates in an assending process.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Yongqun He</obo:IAO_0000117>
        <obo:IAO_0000232 xml:lang="en">This class is under group discussion as of 03/26/2019.</obo:IAO_0000232>
        <rdfs:label xml:lang="en">assenter role</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000170 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000170">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0001000"/>
        <obo:IAO_0000115 xml:lang="en">A questionnaire that is filled up with answers.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Yongqun He, Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000232 xml:lang="en">This class is under group discussion as of 03/26/2019.</obo:IAO_0000232>
        <rdfs:label xml:lang="en">filled questionnaire</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000171 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000171">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000300"/>
        <obo:IAO_0000115 xml:lang="en">A textual entity that is the recorded response to a multiple choice question.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">J. Neil Otte</obo:IAO_0000117>
        <rdfs:label xml:lang="en">filled multiple choice text entity</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000172 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000172">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000171"/>
        <obo:IAO_0000115 xml:lang="en">A filled multiple choice text entity that records a response indicating &apos;yes&apos; to a multiple choice question.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">J. Neil Otte</obo:IAO_0000117>
        <rdfs:label xml:lang="en">yes answer text entity</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000173 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000173">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000171"/>
        <obo:IAO_0000115 xml:lang="en">A filled multiple choice text entity that records a response indicating &apos;no&apos; to a multiple choice question.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">J. Neil Otte</obo:IAO_0000117>
        <rdfs:label xml:lang="en">no answer text entity</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000174 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000174">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
        <obo:IAO_0000115 xml:lang="en">A planned process that involves the filling of an informed consent form.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Yongqun He, Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000232 xml:lang="en">This class is under group discussion as of 03/26/2019.</obo:IAO_0000232>
        <rdfs:label xml:lang="en">filling informed consent form</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000175 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000175">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
        <obo:IAO_0000115 xml:lang="en">A planned process that involves the filling of a questionnaire form that includes a list of questions.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Yongqun He, Asiyah Yu Lin</obo:IAO_0000117>
        <obo:IAO_0000232 xml:lang="en">This class is under group discussion as of 03/26/2019.</obo:IAO_0000232>
        <rdfs:label xml:lang="en">filling questionnaire</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000176 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000176">
        <rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
        <obo:IAO_0000115 xml:lang="en">A deontic role that if realized is realized by its bearer conducting or overseeing genetic research on the genome of a human donor.</obo:IAO_0000115>
        <rdfs:comment xml:lang="en">Note: this term wll be transferred to d-acts. - CTSOG ontology workshop 2018 Little Rock</rdfs:comment>
        <rdfs:label>obsolete permittee deontic role</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000177 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000177">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000196"/>
        <obo:IAO_0000115 xml:lang="en">An informed consent for a subject agrees not to have financial benefit in the future.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Christoph Brochhausen, Yongqun He</obo:IAO_0000117>
        <rdfs:label xml:lang="en">consenting not to have financial benefit</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000178 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000178">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
        <obo:IAO_0000115 xml:lang="en">A planned process for a subject agrees not to be informed about any incidental finding.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Christoph Brochhausen, Yongqun He</obo:IAO_0000117>
        <obo:IAO_0000232 xml:lang="en">This class is under group discussion as of 03/26/2019.</obo:IAO_0000232>
        <rdfs:label xml:lang="en">consenting to not to be informed about incidental finding</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000179 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000179">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
        <obo:IAO_0000115 xml:lang="en">A planned process for an unspecified range of future research subject to a few content or process restrictions.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Frank Manion, Yongqun He, 2018 Little Rock CTSOG ontology workshop</obo:IAO_0000117>
        <obo:IAO_0000119 xml:lang="en">https://www.hhs.gov/ohrp/sachrp-committee/recommendations/attachment-c-august-2-2017/index.html</obo:IAO_0000119>
        <obo:IAO_0000119 xml:lang="en">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791589/</obo:IAO_0000119>
        <obo:IAO_0000232 xml:lang="en">This class is under group discussion as of 03/26/2019.</obo:IAO_0000232>
        <rdfs:label xml:lang="en">broad consent process</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000180 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000180">
        <rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
        <obo:IAO_0000115 xml:lang="en">A broad consent that is for an unspecified range of future research subject to a few content or process restrictions with biological sample.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Yongqun He</obo:IAO_0000117>
        <obo:IAO_0000119 xml:lang="en">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791589/</obo:IAO_0000119>
        <rdfs:label>obsolete process of providing broad consent for research with biological sample</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000181 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000181">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
        <obo:IAO_0000115 xml:lang="en">A planned process that involves a human biological specimen originally collected for the purpose of treatment or a different investigation.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Frank Manion, Yongqun He, 2018 Little Rock CTSOG ontology workshop</obo:IAO_0000117>
        <obo:IAO_0000119 xml:lang="en">https://www.hhs.gov/ohrp/sachrp-committee/recommendations/attachment-c-august-2-2017/index.html</obo:IAO_0000119>
        <obo:IAO_0000119 xml:lang="en">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791589/</obo:IAO_0000119>
        <obo:IAO_0000232 xml:lang="en">Note: not sure if the parent class should be &apos;investigation&apos; or &apos;planned process.&apos;</obo:IAO_0000232>
        <obo:IAO_0000232 xml:lang="en">This definition is provisional, as &apos;secondary use&apos; may apply to non-specimen entities. Adapted from the defintion found here:  https://sunnybrook.ca/research/content/?page=sri-crs-reo-faq-secondaryusedata</obo:IAO_0000232>
        <rdfs:label xml:lang="en">secondary use</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000182 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000182">
        <rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
        <obo:IAO_0000119 xml:lang="en">https://www.ncbi.nlm.nih.gov/pubmed/15360890</obo:IAO_0000119>
        <rdfs:label>obsolete consenting to the secondary use of EHR</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000184 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000184">
        <rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
        <obo:IAO_0000232 xml:lang="en">Note that some of these are defined classes.</obo:IAO_0000232>
        <rdfs:label>obsolete NEW_CLASSES</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000185 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000185">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000085"/>
        <obo:IAO_0000115 xml:lang="en">An informed consent form that is adapted to the cognitive capacities of someone with significant mental impairment.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Yongqun He, Jonathan Vajda</obo:IAO_0000117>
        <rdfs:label xml:lang="en">informed assent form for cognitively impaired</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000186 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000186">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000008"/>
        <obo:IAO_0000115 xml:lang="en">A temporal region during which some act is permitted.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Yongqun He, Jonathan Vajda</obo:IAO_0000117>
        <obo:IAO_0000232 xml:lang="en">This class is under group discussion as of 03/26/2019.</obo:IAO_0000232>
        <rdfs:label xml:lang="en">permission temporal region</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000187 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000187">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
        <obo:IAO_0000115 xml:lang="en">A deontic role, which may be realized in an Act of Consent, where the bearer of the legal representative role consents on behalf of a person who lacks the capability to provide consent.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">J. Neil Otte</obo:IAO_0000117>
        <obo:IAO_0000232 xml:lang="en">It is a requirement of bearing a legal representative role in some jurisdiction(J) that one also bears a competency to consent in (J).</obo:IAO_0000232>
        <obo:IAO_0000232 xml:lang="en">Mathias says this shouldn&apos;t mention &apos;act of consent&apos;. I think the idea is that our definition is narrower than the class label indicates.</obo:IAO_0000232>
        <obo:IAO_0000232 xml:lang="en">Note: Consent roles are created by Acts of Consent. It follows that one can’t be a consenter and bear a consenter role just because one participated in an informed consent process. Here, one would be a mere research candidate or human subject or...etc, who participated in an informed consent process. Assenter Role, likewise, is the output of an Act of Communicating Assent. Both these roles are backward looking--i.e. They are created by the processes of assent and consent and do not pre-date them. By contrast, ‘Legal Representative Role’ and ‘Permission Role’ are not, by definition, tied to Acts of Consenting and Acts of Assenting. Such roles are the output of other processes, including ‘Act of Permitting’ in the latter case, and perhaps ‘Act of Legal Representative Authorization’ in the former.</obo:IAO_0000232>
        <rdfs:label xml:lang="en">legal representative role</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000188 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000188">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000230"/>
        <obo:IAO_0000115 xml:lang="en">A role borne by a human being who is part of a group of individuals and acts as a contact person for the group.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Jonathan Vajda</obo:IAO_0000117>
        <rdfs:label xml:lang="en">organization-specified contact role</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000189 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000189">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000033"/>
        <obo:IAO_0000115 xml:lang="en">A directive information entity that prescribes a human being who is to bear a contact role.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Jonathan Vajda, Cooper Stansbury</obo:IAO_0000117>
        <rdfs:label xml:lang="en">contact directive</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000190 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000190">
        <rdfs:subClassOf rdf:resource="http://www.ontologyrepository.com/CommonCoreOntologies/DescriptiveInformationContentEntity"/>
        <obo:IAO_0000115 xml:lang="en">A descriptive information content entity that describes potential benefit or estimates the likelihood of benefit.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Jonathan Vajda, Cooper Stansbury</obo:IAO_0000117>
        <obo:IAO_0000232 xml:lang="en">This is circulular. &apos;Benefit&apos; and &apos;risk&apos; definitions forthcoming.</obo:IAO_0000232>
        <rdfs:label xml:lang="en">description of participation benefit</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000191 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000191">
        <rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
        <obo:IAO_0000115 xml:lang="en">A document part that describes the action types to be permitted.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Jonathan Vajda</obo:IAO_0000117>
        <rdfs:label>obsolete description of allowed action types</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000192 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000192">
        <rdfs:subClassOf rdf:resource="http://www.ontologyrepository.com/CommonCoreOntologies/DescriptiveInformationContentEntity"/>
        <obo:IAO_0000115 xml:lang="en">A description of allowed action types that has in view a wide, unspecified range of action types, and is restricted only by a regulator body.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Jonathan Vajda, Cooper Stansbury</obo:IAO_0000117>
        <rdfs:label xml:lang="en">description of broad consent</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000193 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000193">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
        <obo:IAO_0000115 xml:lang="en">A planned process of providing information according to prompts on a form.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Jonathan Vajda</obo:IAO_0000117>
        <rdfs:label xml:lang="en">act of filling out form</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000194 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000194">
        <rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
        <obo:IAO_0000115 xml:lang="en">A process that is carried out by a conscious being or an aggregate of conscious beings, and is spontaneous, directed towards another conscious being or another aggregate of conscious beings, and that needs to be perceived.</obo:IAO_0000115>
        <obo:IAO_0000232 xml:lang="en">This is a D-Act Term, included here as a placeholder untill D-acts is imported.</obo:IAO_0000232>
        <rdfs:label>obsolete social act (placeholder)</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000195 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000195">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0021009"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/OBI_0000299"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/ICO_0000199"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <obo:IAO_0000115 xml:lang="en">A social act in which an agent bearing a deontic power role and realizes that role in the creation of a permission role.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">J. Neil Otte</obo:IAO_0000117>
        <obo:IAO_0000232 xml:lang="en">Axiom: Every ‘Act of permitting’ has process part some (‘Speech Act’ or ‘Document Act’).
Note: This class is very general, and doesn’t only apply to consent and healthcare contexts.</obo:IAO_0000232>
        <obo:IAO_0000232 xml:lang="en">In contrast to the &apos;authentication&apos; (see OMRSE), an act of permitting always involves a flow of power, in which one who grants permission has a power, and the agent to whom permission is granted gains access to a power that flows from that of the granter. By contrast, although it may be the case that a person who authenticates has power, this power is only the power to authenticate or verify, and this power does not flow to the authenticated document or identity.</obo:IAO_0000232>
        <obo:IAO_0000232 xml:lang="en">Note: ‘Act of permitting’, ‘act of consenting’, and ‘act of communicating assent’ are all success terms, which is to say that no ‘act of permitting’ does not issue a permission, no ‘act of consenting’ does not issue a consent, and no ‘act of communicating assent’ does not issue an assent.</obo:IAO_0000232>
        <rdfs:label xml:lang="en">act of permitting</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000196 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000196">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/ICO_0000195"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000810"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000195"/>
        <obo:IAO_0000115 xml:lang="en">An act of permitting that is a process part of some informed consent process.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">J. Neil Otte</obo:IAO_0000117>
        <obo:IAO_0000232 xml:lang="en">Note: This class is very general, and doesn’t only apply to consent and healthcare contexts. There may be further subclasses of consenting for which there are also required process parts, such as a process of informing a patient of the risks associated with a medical procedure or research investigation.

Also, 6/28: Mathias writes: This definition is probably incorrect. I assume we don&apos;t want to affirm that only within informed consent we do find acts of consenting.</obo:IAO_0000232>
        <rdfs:label xml:lang="en">act of informed consenting</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000197 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000197">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0021003"/>
        <obo:IAO_0000115 xml:lang="en">An act of communicating one’s agreement.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">J. Neil Otte</obo:IAO_0000117>
        <rdfs:label xml:lang="en">act of communicating assent</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000198 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000198">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000033"/>
        <obo:IAO_0000115>A directive information entity that prescribes whether, under what conditions, and with which recipients biospecimens (including human biological materials and their derivatives) may be shared beyond the original study team or repository.</obo:IAO_0000115>
        <obo:IAO_0000117>Rahma Alifia, Jie Zheng, Tuan Amith, Oliver He</obo:IAO_0000117>
        <obo:IAO_0000118>directive about specimen sharing</obo:IAO_0000118>
        <obo:IAO_0000118>directive information entity about specimen sharing</obo:IAO_0000118>
        <obo:IAO_0000233>https://github.com/ICO-ontology/ICO/issues/39</obo:IAO_0000233>
        <rdfs:label xml:lang="en">specimen sharing directive</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000199 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000199">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0021008"/>
        <obo:IAO_0000115 xml:lang="en">A deontic role that inheres in an agent and which permits certain actions.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">J. Neil Otte</obo:IAO_0000117>
        <obo:IAO_0000232 xml:lang="en">Important Note: When we use ‘consent’ to talk about the thing provided to an investigator then what we are referring to is a permission role, that was the output of an Act of Consent. This is all consent is, per this representation.</obo:IAO_0000232>
        <obo:IAO_0000232 xml:lang="en">Note: This may become ‘permittee role’ in order to better distinguish it from the corresponding ‘permittor role’ (the person with the deontic power to grant permissions to others).</obo:IAO_0000232>
        <obo:IAO_0000232 xml:lang="en">Note: Typically, in the context of consent, a permission role will inhere in a clinician or investigator as a result of an act of permitting, but possibly an act of authorizing. Authorizing is different from permitting, but this needs to be worked out. Perhaps one has provided permission, but the process and the documentation need to be authorized by some authority prior to a clinician acquiring a permission role. There is also the case Chris Stockert raised, where an organization authorizes some data or specimens to be used, despite no consent or assent having been provided.</obo:IAO_0000232>
        <rdfs:label xml:lang="en">permission role</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000200 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000200">
        <rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
        <obo:IAO_0000115 xml:lang="en">A deontic power role that, if realized, may permit an Act of Consent and thereby create a permission role, or revoke or modify a previously provided permission role created by permitting an Act of Consent.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">J. Neil Otte</obo:IAO_0000117>
        <obo:IAO_0000232 xml:lang="en">Note: A Consent Power Role inheres in all those who bear a legal right to consent. Such a role represents a de jure right that holds within some socio-legal jurisdiction. It follows that one may bear an instance of a consent power role within one jurisdiction but one may lack an instance of a consent power role within a second jurisdiction, given that one’s  capability to consent may satisfy legal conditions in the former jurisdiction but not in the latter.</obo:IAO_0000232>
        <rdfs:label>obsolete consent power role</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000201 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000201">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000016"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/ICO_0000220"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <obo:IAO_0000115 xml:lang="en">A cognitive capability inhering in some agent, which may be realized in an Act of Consent.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">J. Neil Otte</obo:IAO_0000117>
        <obo:IAO_0000232 xml:lang="en">Note: Capability-talk is fraught and so attention to this particular, somewhat stipulative notion is necessary.
First: Capabilities are BFO:Dispositions. Hence, we’re not talking about institutional power, which will be represented separately using deontic roles. This is compatible with institutional rules requiring a particular capability.
Second: Like roles, capabilities can have other capabilities as parts. Thus, the capability to consent requires, as part, the capability to understand information, the capability to appreciate the consequences of one’s actions, and other capabilities related to a basic, agential capacity to be reasons-responsive. These capacities may be realized in other sub-parts of the informed consent process, and they may be identified in processes of cognitive assessment.
	Third: Capabilities may be assessed along a scale, with some having a greater capability to consent and some having a lesser ability to consent. The same capability at the same degree may pass muster in some jurisdictions but fail to pass in others. When it does succeed in passing some legal requirement, then the bearer of the capability has a Consent Power Role and their capability to consent now counts as a competency.
	Fourth: Capabilities are cognitive dispositions. As such, the class ‘capability to consent’ is not intended to be a catch-all for all the necessary conditions for legal consent. For instance, being under the age of 18 is not part of an instance of a capability to consent, but the capability to understand risks and benefits may be.
Fifth: A capability that is so low on the scale as to not pass any tests is no longer a capability but a liability. The distinction between capabilities and liabilities may not be vague ontologically, but may be quite difficult to suss out epistemologically. More to the point: This is perhaps the most revisionist aspect of this reading of capabilities, for it requires that in some particular legal context, we might need to say that someone has a capability to consent that is sufficiently low as to not qualify as a competency within that legal context. Since ‘capability’ is often also used in a bi-valent, non-scalable manner (i.e. one either is capable or one is not capable) the notion here involves some stipulation. For this bi-valent notion, we use ‘competent’ (i.e. one either is competent or incompetent).
	In addition as of this writing (July 2018): There is work on capabilities occurring presently within the National Center for Ontological Research (NCOR), so this reading of capabilities may need revising as that work moves forward.</obo:IAO_0000232>
        <rdfs:label xml:lang="en">capability to consent</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000202 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000202">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000201"/>
        <obo:IAO_0000115 xml:lang="en">A capability to consent that is sufficiently robust as to pass the legal requirements of some jurisdiction.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">J. Neil Otte</obo:IAO_0000117>
        <obo:IAO_0000232 xml:lang="en">Axiom: all l all c all t all m (competencytoconsent(m) &amp; inheresin(m,x,t) -&gt; (exists l exists c (legalpowerrole(l) &amp; capabilitytoconsent(c) &amp; (exists r exists o (hasorganizationalcontext(l,r,t) &amp; hasorganizationalcontext(l,o,t) &amp; r=o)) &amp; inheresin(l,x,t) &amp; inheresin(c,x,t)) -&gt; (m=c))).

%If one bears a competency to consent, then one bears a legal power role and a capability to consent in the same legal context at the same time and the competency to consent is identical to the capability to consent.</obo:IAO_0000232>
        <obo:IAO_0000232 xml:lang="en">One may have the same capability to consent, but whether that capability to consent amounts to a competency might vary between jurisdictions that impose different requirements upon the bearer.</obo:IAO_0000232>
        <rdfs:label xml:lang="en">competency to consent</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000203 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000203">
        <rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
        <obo:IAO_0000115 xml:lang="en">A role that is the output of an act of assent and which inheres in a human being, who, because they fail to satisfy certain criteria for consent, is thereby allowed the aid of a legal representative who aids them in an Act of Consent, and, in some contexts, may be realized in revoking or modifying the permission role that was output of the informed consent process of which the the Act of Assent was a process part.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">J. Neil Otte</obo:IAO_0000117>
        <rdfs:label>obsolete assenter role</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000204 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000204">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/ICO_0000220"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/ICO_0000225"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/ICO_0000197"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000220"/>
        <obo:IAO_0000115 xml:lang="en">An agent who has communicated their assent.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">J. Neil Otte</obo:IAO_0000117>
        <rdfs:label xml:lang="en">assenter</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000205 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000205">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000053"/>
                        <owl:someValuesFrom>
                            <owl:Class>
                                <owl:intersectionOf rdf:parseType="Collection">
                                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/ICO_0000223"/>
                                    <owl:Restriction>
                                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000054"/>
                                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/ICO_0000196"/>
                                    </owl:Restriction>
                                </owl:intersectionOf>
                            </owl:Class>
                        </owl:someValuesFrom>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:IAO_0000115 xml:lang="en">An agent who, at some time, was the bearer of a consent power role, which was, in fact, realized in an act of informed consenting, and who, as a result of this act of informed consenting, now bears a consenter role.</obo:IAO_0000115>
        <obo:IAO_0000116 xml:lang="en">A consenter role may be realized, for example, in the withdraw of consent.</obo:IAO_0000116>
        <obo:IAO_0000117 xml:lang="en">J. Neil Otte</obo:IAO_0000117>
        <rdfs:label xml:lang="en">consenter</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000206 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000206">
        <rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
        <obo:IAO_0000115 xml:lang="en">A deontic role that is output of some Act of Consent and, in some contexts, may be realized in revoking or modifying the permission role that was output of the same Act of Consent.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">J. Neil Otte</obo:IAO_0000117>
        <obo:IAO_0000232 xml:lang="en">May be deleted. Consenter role just seems like permission role issued by an act of consenting.</obo:IAO_0000232>
        <rdfs:label>obsolete consenter role</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000213 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000213">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000001"/>
        <obo:IAO_0000115 xml:lang="en">A document act input document that explains all relevant information to assist a human being in understanding the expectations and requirements of participation in a process, and whose purpose is to assist in obtaining consent.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">J. Neil Otte</obo:IAO_0000117>
        <rdfs:comment xml:lang="en">Note: instances of &apos;incomplete informed consent form&apos; include both blank informed consent forms that are waiting to be used in a process of informed consent, as well as those that have been left blank by a patient, whether on purpose or in error. Those that have been left blank on purpose have been used in a process of informed consent, where the patient must have reached a decision.</rdfs:comment>
        <rdfs:label xml:lang="en">incomplete informed consent form</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000214 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000214">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000001"/>
        <obo:IAO_0000115 xml:lang="en">A document act input document that has, as part, an incomplete informed consent form, along with some additional parts, such as a signature, stamp, or initials, which serve as a record to an act of consent that had the incomplete informed consent form as a specified input.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">J. Neil Otte</obo:IAO_0000117>
        <rdfs:label xml:lang="en">complete informed consent form indicating consent</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000215 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000215">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0021008"/>
        <obo:IAO_0000115 xml:lang="en">A deontic role that, if realized, is realized in the creation, modification, or revoking of other deontic roles.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">J. Neil Otte</obo:IAO_0000117>
        <rdfs:label xml:lang="en">deontic power role</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000217 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000217">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
        <obo:IAO_0000115 xml:lang="en">A planned process that involves altering an information content entity that is associated with an individual, such that such association is lost or inaccessible.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Jonathan Vajda</obo:IAO_0000117>
        <rdfs:label xml:lang="en">act of anonymizing</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000218 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000218">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000217"/>
        <obo:IAO_0000115 xml:lang="en">An act of anonymization that alters an information content entity by removing information content which identifies that individual.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Jonathan Vajda</obo:IAO_0000117>
        <rdfs:label xml:lang="en">act of removing identifiable information</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000220 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000220">
        <owl:equivalentClass>
            <owl:Class>
                <owl:unionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000245"/>
                </owl:unionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
        <obo:IAO_0000115 xml:lang="en">A material entity (either a human being or an aggregate of humans such as an organization) which is active in a process or has the relevant capabilities of intentionality.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Jonathan Vajda</obo:IAO_0000117>
        <rdfs:label xml:lang="en">agent</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000221 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000221">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0021003"/>
        <obo:IAO_0000115 xml:lang="en">A social act in which information that is thought to be true, salient, or which is held to have a high degree of certainty is communicated to an agent that previously lacked that information.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Jonathan Vajda, J. Neil Otte</obo:IAO_0000117>
        <obo:IAO_0000232 xml:lang="en">If I communicate falsehoods, I do not inform--I mis-inform.</obo:IAO_0000232>
        <rdfs:label xml:lang="en">act of informing</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000222 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000222">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000030"/>
        <obo:IAO_0000115 xml:lang="en">An information content entity that is a handwritten depiction of a name.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Jonathan Vajda, Cooper Stansbury, J. Neil Otte.</obo:IAO_0000117>
        <rdfs:label xml:lang="en">signature</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000223 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000223">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000215"/>
        <obo:IAO_0000115 xml:lang="en">A deontic power role that may be realized in an act of consent that is a process part of an informed consent process.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">J. Neil Otte</obo:IAO_0000117>
        <obo:IAO_0000232 xml:lang="en">a consent power role is a legal right that holds within a jurisdiction and is a necessary requirement to bear a competency to consent.</obo:IAO_0000232>
        <rdfs:label xml:lang="en">consent power role</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000226 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000226">
        <rdfs:subClassOf rdf:resource="http://www.ontologyrepository.com/CommonCoreOntologies/StasisOfGenericallyDependentContinuant"/>
        <obo:IAO_0000115 xml:lang="en">A stasis of generically dependent continuant that has participant some information content entity which, during the stasis, is unable to be used to identify some agent which the information is about.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Jonathan Vajda, Cooper Stansbury, J. Neil Otte</obo:IAO_0000117>
        <obo:IAO_0000232 xml:lang="en">An information content entity that has previously undergone the process &apos;act of anonymization&apos; participates in this stasis.</obo:IAO_0000232>
        <obo:IAO_0000232 xml:lang="en">We expect to add a subclass axiom: &apos;preceded by&apos; some &apos;Act of Anonymizing&apos;</obo:IAO_0000232>
        <rdfs:label xml:lang="en">stasis of anonymization</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000227 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000227">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
        <obo:IAO_0000115 xml:lang="en">A planned process that involves placing a material entity in some location in order to maintain possession of it.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">J. Neil Otte</obo:IAO_0000117>
        <rdfs:label xml:lang="en">act of storing</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000228 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000228">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
        <obo:IAO_0000115 xml:lang="en">A planned process in which data possessed by one person or organization is shared with one or more other persons or organizations.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">J. Neil Otte</obo:IAO_0000117>
        <rdfs:label xml:lang="en">act of data sharing</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000229 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000229">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000230"/>
        <obo:IAO_0000115 xml:lang="en">A contact person role that is the output of either a human subject or patient assigning that person as their point of contact.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">J. Neil Otte</obo:IAO_0000117>
        <obo:IAO_0000118 xml:lang="en">emergency contact role</obo:IAO_0000118>
        <rdfs:label xml:lang="en">human subject-specified contact person role</rdfs:label>
        <rdfs:seeAlso xml:lang="en">organization-specified contact role</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000230 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000230">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
        <obo:IAO_0000115 xml:lang="en">A role inhering in a person who is a designated contact for some other agent.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">J. Neil Otte</obo:IAO_0000117>
        <rdfs:comment xml:lang="en">The subclasses of &apos;contact person role&apos; distinguish two types: a contact person who has been designated by an organization for others (primarily patients and human research subjects in clinical settings) to contact, and a contact person whom an agent has specified for an organization to contact in the event that the organization needs to contact the patient. Examples of the latter include &apos;emergency contact&apos; persons, who are frequently specified in a form.</rdfs:comment>
        <rdfs:label xml:lang="en">contact person role</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000231 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000231">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000029"/>
        <obo:IAO_0000115 xml:lang="en">A site within which a deontic power may be realized, where that deontic power inheres in a formally created regulatory body.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury</obo:IAO_0000117>
        <obo:IAO_0000117 xml:lang="en">J. Neil Otte</obo:IAO_0000117>
        <obo:IAO_0000117 xml:lang="en">Jonathan Vajda</obo:IAO_0000117>
        <obo:IAO_0000232 xml:lang="en">&apos;Jurisdiction&apos; is often defined in two senses: (1) a geopolitical context (BFO site), or (2) a power. We define jurisdiction as a BFO site, identifiable through shared context of other entities, like a country or state border, or the grounds of an institution. The term ‘deontic power role’ reflects the sense of ‘power’ sometimes used to describe jurisdiction.</obo:IAO_0000232>
        <rdfs:label xml:lang="en">jurisdiction</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000232 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000232">
        <rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
        <obo:IAO_0000115 xml:lang="en">An organization that has a deontic power role prescribed by some regulatory document that occurs in a stasis of regulation.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury</obo:IAO_0000117>
        <obo:ICO_0000321 xml:lang="en"></obo:ICO_0000321>
        <rdfs:label>obsolete regulatory body</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000233 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000233">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000310"/>
        <obo:IAO_0000115 xml:lang="en">A document that either prescribes actions or prescribes the permissions, obligations, restrictions, or protections relating to public or legal policy.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury</obo:IAO_0000117>
        <obo:IAO_0000232 xml:lang="en">Rules, legal specifications, guidelines (both categorical and hypothetical), that exist together in one regulatory document. Regulations may contain a single, or multiple rules.</obo:IAO_0000232>
        <obo:IAO_0000232 xml:lang="en">The clause ‘permissions, obligations, restrictions, or protections’ will be replaced with more general superclass, likely from d-acts, when that infrastructure becomes available. IOU Code.</obo:IAO_0000232>
        <obo:ICO_0000321 xml:lang="en"></obo:ICO_0000321>
        <rdfs:label xml:lang="en">regulatory document</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000234 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000234">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000233"/>
        <obo:IAO_0000112 xml:lang="en">‘HIPAA documents,’ ‘The Common Rule,’ an ‘Informed Consent Regulatory Document.’</obo:IAO_0000112>
        <obo:IAO_0000115 xml:lang="en">A regulatory document designed to prescribe research involving human subjects.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury</obo:IAO_0000117>
        <obo:ICO_0000321 xml:lang="en"></obo:ICO_0000321>
        <rdfs:label xml:lang="en">human subject research regulatory document</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000235 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000235">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000233"/>
        <obo:IAO_0000115 xml:lang="en">A regulatory document designed to prescribe an informed consent process or inputs in an informed consent process.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury</obo:IAO_0000117>
        <obo:IAO_0000425 xml:lang="en">‘Informed Consent Waivers,’ ‘Informed Consent Exemptions.’</obo:IAO_0000425>
        <obo:ICO_0000321 xml:lang="en"></obo:ICO_0000321>
        <rdfs:label xml:lang="en">informed consent regulatory document</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000236 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000236">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000055"/>
        <obo:IAO_0000112 xml:lang="en">Do action (x).</obo:IAO_0000112>
        <obo:IAO_0000115 xml:lang="en">A rule in an informed consent regulatory document that prescribes either an informed consent process or deontic roles inhering in agents that participate in an informed consent process.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury</obo:IAO_0000117>
        <obo:ICO_0000321 xml:lang="en"></obo:ICO_0000321>
        <rdfs:label xml:lang="en">informed consent rule</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000237 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000237">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000055"/>
        <obo:IAO_0000115 xml:lang="en">A rule in an informed consent regulatory document that prescribes an informed consent process and has part trigger condition description.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury</obo:IAO_0000117>
        <obo:IAO_0000232 xml:lang="en">Those conditions that have important implications are enumerated in a specification of condition.</obo:IAO_0000232>
        <obo:IAO_0000600 xml:lang="en">The logical form of a conditional rule is as follows: if condition (y) obtains, then perform action (x).</obo:IAO_0000600>
        <obo:ICO_0000321 xml:lang="en"></obo:ICO_0000321>
        <rdfs:label xml:lang="en">conditional informed consent rule</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000238 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000238">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000055"/>
        <obo:IAO_0000115 xml:lang="en">A rule in an informed consent regulatory document that prescribes deontic roles that may be realized in an unspecified range of activities, or which is subject to few restrictions.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury</obo:IAO_0000117>
        <obo:ICO_0000321 xml:lang="en"></obo:ICO_0000321>
        <rdfs:label xml:lang="en">broad consent rule</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000239 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000239">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000033"/>
        <obo:IAO_0000115 xml:lang="en">A directive information entity that prescribes information that must be revealed and prescribes to whom that information must be revealed.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury</obo:IAO_0000117>
        <obo:ICO_0000321 xml:lang="en"></obo:ICO_0000321>
        <rdfs:label xml:lang="en">disclosure directive</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000240 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000240">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000033"/>
        <obo:IAO_0000112 xml:lang="en">A description of who can consent (but not the conditions required to be realizable).</obo:IAO_0000112>
        <obo:IAO_0000115 xml:lang="en">A directive information entity that prescribes a deontic power role or the process that realizes it.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury</obo:IAO_0000117>
        <obo:ICO_0000321 xml:lang="en"></obo:ICO_0000321>
        <rdfs:label xml:lang="en">deontic power role directive</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000241 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000241">
        <rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
        <obo:IAO_0000115 xml:lang="en">A directive information entity that prescribes the limits of disclosure regarding an agent’s identity.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury</obo:IAO_0000117>
        <obo:IAO_0000232 xml:lang="en">May need ‘Conditional Confidentiality Directive&apos; in the future.</obo:IAO_0000232>
        <obo:ICO_0000321 xml:lang="en"></obo:ICO_0000321>
        <rdfs:label>obsolete confidentiality directive</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000242 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000242">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000033"/>
        <obo:IAO_0000112 xml:lang="en">A ‘signature section,’ an ‘I understand’ clause, or a ‘checkbox.’</obo:IAO_0000112>
        <obo:IAO_0000115 xml:lang="en">A directive information entity that, when signed, stamped, or initialed realizes a deontic role as described by the document specifications, or specifications in another related document.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury</obo:IAO_0000117>
        <obo:ICO_0000321 xml:lang="en"></obo:ICO_0000321>
        <rdfs:label xml:lang="en">user input directive</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000243 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000243">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000033"/>
        <obo:IAO_0000115 xml:lang="en">A directive information entity that enumerates the results if a trigger condition describing failure to comply with a rule is met.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, J. Neil Otte, Jonathan Vajda</obo:IAO_0000117>
        <obo:ICO_0000321 xml:lang="en"></obo:ICO_0000321>
        <rdfs:label xml:lang="en">consequent directive</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000244 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000244">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000033"/>
        <obo:IAO_0000115 xml:lang="en">A &apos;directive information entity&apos; that prescribes an allowable action,  where that action is otherwise impermissible.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield, Kathleen Ford, Marcy Harris</obo:IAO_0000117>
        <obo:ICO_0000404 xml:lang="en"></obo:ICO_0000404>
        <rdfs:comment xml:lang="en">(1) There is some ambiguity regarding process repition. This distinction may point to the central question of whether or not we permit &apos;universals&apos; or . Take the following example: In the case of &apos;permission to destroy excess tissue&apos; the instance of a &apos;process of destruction&apos; is permitted only once.  However, in the case of &apos;pemission to share data&apos; this process may be performed multiple times.</rdfs:comment>
        <rdfs:label xml:lang="en">permission directive</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000245 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000245">
        <rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
        <obo:IAO_0000115 xml:lang="en">A conditional specification that prescirbes a permission, should some trigger condition obtain.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury</obo:IAO_0000117>
        <obo:IAO_0000600 xml:lang="en">Permission to do (x), if condition (y).</obo:IAO_0000600>
        <obo:ICO_0000321 xml:lang="en"></obo:ICO_0000321>
        <rdfs:label>obsolete conditional permission directive</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000246 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000246">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000033"/>
        <obo:IAO_0000115 xml:lang="en">A directive information entity that prescribes actions that are impermissible.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury</obo:IAO_0000117>
        <obo:IAO_0000600 xml:lang="en">When particpating in an informed consent process (a), do not do action (y).</obo:IAO_0000600>
        <obo:ICO_0000321 xml:lang="en"></obo:ICO_0000321>
        <rdfs:label xml:lang="en">restriction directive</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000247 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000247">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000001"/>
        <obo:IAO_0000115 xml:lang="en">A conditional specification that prescirbes an impermissibility, should some trigger condition obtain.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury and J. Neil Otte</obo:IAO_0000117>
        <obo:IAO_0000600 xml:lang="en">When particpating in an informed consent process (a), if conditon (x) do not do action (y).</obo:IAO_0000600>
        <obo:ICO_0000321 xml:lang="en"></obo:ICO_0000321>
        <rdfs:label xml:lang="en">conditional restriction directive</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000248 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000248">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000033"/>
        <obo:IAO_0000115 xml:lang="en">A directive information entity that prescribes an obligation that is realized a deontic role that is the output of a document act.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury</obo:IAO_0000117>
        <obo:ICO_0000321 xml:lang="en"></obo:ICO_0000321>
        <rdfs:label xml:lang="en">obligation directive</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000249 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000249">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000001"/>
        <obo:IAO_0000115 xml:lang="en">A conditional specification that prescirbes an obligation, should some trigger condition obtain.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury and J. Neil Otte</obo:IAO_0000117>
        <obo:ICO_0000321 xml:lang="en"></obo:ICO_0000321>
        <rdfs:label xml:lang="en">conditional obligation directive</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000250 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000250">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000033"/>
        <obo:IAO_0000115 xml:lang="en">A directive information entity that prescribes the agent that is liable if a trigger condition is met.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury</obo:IAO_0000117>
        <obo:ICO_0000321 xml:lang="en"></obo:ICO_0000321>
        <rdfs:label xml:lang="en">liability directive</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000251 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000251">
        <rdfs:subClassOf rdf:resource="http://www.ontologyrepository.com/CommonCoreOntologies/DescriptiveInformationContentEntity"/>
        <obo:IAO_0000112 xml:lang="en">The section of an informed consent document that describes a clinical procedure that the agent is consenting to.</obo:IAO_0000112>
        <obo:IAO_0000115 xml:lang="en">A descriptive information content entity that describes a medical procedure.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury</obo:IAO_0000117>
        <obo:ICO_0000321 xml:lang="en"></obo:ICO_0000321>
        <rdfs:label xml:lang="en">description of medical procedure</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000252 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000252">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000033"/>
        <obo:IAO_0000115 xml:lang="en">A directive information entity that describes some state of affairs such that, if that state of affairs holds, some other prescription follows.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury</obo:IAO_0000117>
        <obo:IAO_0000232 xml:lang="en">An antecedent.</obo:IAO_0000232>
        <obo:ICO_0000321 xml:lang="en"></obo:ICO_0000321>
        <rdfs:label xml:lang="en">trigger condition directive</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000253 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000253">
        <rdfs:subClassOf rdf:resource="http://www.ontologyrepository.com/CommonCoreOntologies/DescriptiveInformationContentEntity"/>
        <obo:IAO_0000117 xml:lang="en">A descriptive information content entity that reports that participation in the procedures described elsewhere in the document are voluntary.</obo:IAO_0000117>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury</obo:IAO_0000117>
        <obo:ICO_0000321 xml:lang="en"></obo:ICO_0000321>
        <rdfs:label xml:lang="en">description of voluntary participation</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000254 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000254">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
        <obo:IAO_0000115 xml:lang="en">A role inhering in an agent as a result of that agent having observed some process.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">J. Neil Otte and Cooper Stansbury</obo:IAO_0000117>
        <obo:IAO_0000600 xml:lang="en">Typically, someone who bears a witness role has observed some history, such that one may attest to what has occurred.</obo:IAO_0000600>
        <obo:ICO_0000321 xml:lang="en"></obo:ICO_0000321>
        <rdfs:label xml:lang="en">witness role</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000255 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000255">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000033"/>
        <obo:IAO_0000115 xml:lang="en">A directive information entity that prescribes some process for withdraw from another planned process.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury and J. Neil Otte</obo:IAO_0000117>
        <obo:ICO_0000321 xml:lang="en"></obo:ICO_0000321>
        <rdfs:label xml:lang="en">withdrawal from participation directive</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000256 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000256">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000030"/>
        <obo:IAO_0000115 xml:lang="en">A temporal region identifier that designates the temporal region during which a living person is alive, and where the temporal region is such that the living person is qualified to exercise a deontic power within a legal jurisdiction.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">J. Neil Otte</obo:IAO_0000117>
        <obo:ICO_0000321 xml:lang="en"></obo:ICO_0000321>
        <rdfs:label xml:lang="en">legal age</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000257 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000257">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0021003"/>
        <obo:IAO_0000115 xml:lang="en">A social act in which formal or official endorsement of some entity is communicated.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">J. Neil Otte and Cooper Stansbury</obo:IAO_0000117>
        <obo:ICO_0000321 xml:lang="en"></obo:ICO_0000321>
        <rdfs:comment xml:lang="en">This &apos;act of approving&apos; is distinct from the mental act of approving.</rdfs:comment>
        <rdfs:label xml:lang="en">act of approving</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000258 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000258">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000033"/>
        <obo:IAO_0000115 xml:lang="en">A directive information entity that prescribes the language that must be used in an informed consent process.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury and J. Neil Otte</obo:IAO_0000117>
        <obo:ICO_0000321 xml:lang="en"></obo:ICO_0000321>
        <rdfs:label xml:lang="en">consent language directive</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000259 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000259">
        <rdfs:subClassOf rdf:resource="http://www.ontologyrepository.com/CommonCoreOntologies/DescriptiveInformationContentEntity"/>
        <obo:IAO_0000115 xml:lang="en">A descriptive information content entity that describes some process that may be elected.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">J. Neil Otte, Cooper Stansbury, Jonathan Vajda</obo:IAO_0000117>
        <obo:ICO_0000321 xml:lang="en"></obo:ICO_0000321>
        <rdfs:label xml:lang="en">description of alternative</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000260 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000260">
        <rdfs:subClassOf rdf:resource="http://www.ontologyrepository.com/CommonCoreOntologies/DescriptiveInformationContentEntity"/>
        <obo:IAO_0000115 xml:lang="en">A descriptive information content entity that describes expressions or implications of threat that may compel an agent to act out of fear against the agent&apos;s will.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury and J. Neil Otte</obo:IAO_0000117>
        <obo:IAO_0000232 xml:lang="en">It may be necessary to define processes of coercion in addition to descriptions of the process.</obo:IAO_0000232>
        <obo:IAO_0000600 xml:lang="en">An international review board (IRB) may require a research proposal to identify ways in which a participant may be under undue influence. For example, a prisoner may feel compelled, given their vulnerability, to provide more information or cooperation in a study than they would normally consent to, because of the benefits they might receive.</obo:IAO_0000600>
        <obo:ICO_0000321 xml:lang="en"></obo:ICO_0000321>
        <rdfs:label xml:lang="en">description of coercion</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000261 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000261">
        <rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
        <obo:IAO_0000232 xml:lang="en">&quot;§46.102(f) Human subject means a living individual about whom an investigator (whether professional or student) conducting research obtains (1) Data through intervention or interaction with the individual, or 2) Identifiable private information. Intervention includes both physical procedures by which data are gathered (for example, venipuncture) and manipulations of the subject or the subject&apos;s environment that are performed for research purposes. Interaction includes communication or interpersonal contact between investigator and subject. Private information includes information about behavior that occurs in a context in which an individual can reasonably expect that no observation or recording is taking place, and information which has been provided for specific purposes by an individual and which the individual can reasonably expect will not be made public (for example, a medical record). Private information must be individually identifiable (i.e., the identity of the subject is or may readily be ascertained by the investigator or associated with the information) in order for obtaining the information to constitute research involving human subjects.&quot;</obo:IAO_0000232>
        <obo:ICO_0000321 xml:lang="en"></obo:ICO_0000321>
        <rdfs:label>obsolete information about participant</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000262 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000262">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000016"/>
        <obo:IAO_0000115 xml:lang="en">A disposition to abnormality realized in cognitive processes that are qualitatively below those of individuals belonging to some type, to which the bearer of the disposition also belongs.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">J. Neil Otte</obo:IAO_0000117>
        <obo:IAO_0000119 rdf:resource="http://purl.obolibrary.org/obo/HP_0100543"/>
        <obo:IAO_0000232 xml:lang="en">Adapted from http://purl.obolibrary.org/obo/HP_0100543</obo:IAO_0000232>
        <obo:ICO_0000321 xml:lang="en"></obo:ICO_0000321>
        <dc:date xml:lang="en">Imported and adapted 8.22.2018</dc:date>
        <rdfs:label xml:lang="en">cognitive impairment</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000263 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000263">
        <rdfs:subClassOf rdf:resource="http://purl.unep.org/sdg/SDGIO_00000024"/>
        <obo:IAO_0000115 xml:lang="en">A vulnerability due to exposure to a depressed or impoverished economic environment.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Jonathan Vajda</obo:IAO_0000117>
        <obo:ICO_0000321 xml:lang="en"></obo:ICO_0000321>
        <rdfs:label xml:lang="en">economic vulnerability</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000264 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000264">
        <rdfs:subClassOf rdf:resource="http://purl.unep.org/sdg/SDGIO_00000024"/>
        <obo:IAO_0000115 xml:lang="en">A vulnerability due to exposure to a harsh learning environment.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Jonathan Vajda</obo:IAO_0000117>
        <obo:ICO_0000321 xml:lang="en"></obo:ICO_0000321>
        <rdfs:label xml:lang="en">educational vulnerability</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000265 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000265">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
        <obo:IAO_0000115 xml:lang="en">A planned process of storing the document output of an &apos;act of consent&apos; for future use.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury and J. Neil Otte</obo:IAO_0000117>
        <obo:ICO_0000321 xml:lang="en"></obo:ICO_0000321>
        <rdfs:label xml:lang="en">act of archiving informed consent</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000266 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000266">
        <rdfs:subClassOf rdf:resource="http://www.ontologyrepository.com/CommonCoreOntologies/DescriptiveInformationContentEntity"/>
        <obo:IAO_0000115 xml:lang="en">A descriptive information content entity that describes a method of some act of communicating.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Jonathan Vajda</obo:IAO_0000117>
        <obo:ICO_0000321 xml:lang="en"></obo:ICO_0000321>
        <rdfs:label xml:lang="en">contact method description</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000267 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000267">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000033"/>
        <obo:IAO_0000115 xml:lang="en">A directive information entity that prescribes some process in which vulnerable individuals participate.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury and J. Neil Otte</obo:IAO_0000117>
        <obo:ICO_0000321 xml:lang="en"></obo:ICO_0000321>
        <rdfs:label xml:lang="en">vulnerable population directive</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000268 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000268">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000033"/>
        <obo:IAO_0000115 xml:lang="en">A directive information entity that prescribes the nondisclosure of information.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury and J. Neil Otte</obo:IAO_0000117>
        <obo:ICO_0000321 xml:lang="en"></obo:ICO_0000321>
        <rdfs:label xml:lang="en">confidentiality directive</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000269 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000269">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0021003"/>
        <obo:IAO_0000115 xml:lang="en">A planned process in which some entity provides information to another entity.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury and J. Neil Otte</obo:IAO_0000117>
        <obo:IAO_0000119 xml:lang="en">adapted from &quot;communicate.&quot; Merriam-Webster.com. 2011. https://www.merriam-webster.com (30 August 2018).</obo:IAO_0000119>
        <obo:IAO_0000232 xml:lang="en">See ICO: &apos;act of informing.&apos; This class is perhaps not needed.</obo:IAO_0000232>
        <obo:ICO_0000321 xml:lang="en"></obo:ICO_0000321>
        <rdfs:comment xml:lang="en">A note: &apos;entity&apos; rather than &apos;agent&apos; is used in this definition in order to allow that software can communicate with other software. However, it should be noted that this definition of communication excludes broader meanings, such as unintentional sharing of information.</rdfs:comment>
        <rdfs:label xml:lang="en">act of communicating</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000270 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000270">
        <rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
        <obo:ICO_0000321 xml:lang="en"></obo:ICO_0000321>
        <rdfs:label>obsolete benefit</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000271 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000271">
        <rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
        <obo:ICO_0000321 xml:lang="en"></obo:ICO_0000321>
        <rdfs:label>obsolete risk</rdfs:label>
        <owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000272 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000272">
        <rdfs:subClassOf rdf:resource="http://www.ontologyrepository.com/CommonCoreOntologies/DescriptiveInformationContentEntity"/>
        <obo:IAO_0000117 xml:lang="en">A descriptive information content entity that describes the expected duration of participation of some agent in an investigation.</obo:IAO_0000117>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury</obo:IAO_0000117>
        <obo:ICO_0000321 xml:lang="en"></obo:ICO_0000321>
        <rdfs:label xml:lang="en">description of expected study participation duration</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000273 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000273">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000033"/>
        <obo:IAO_0000115 xml:lang="en">A directive information entity that prescribes some research process.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury and J. Neil Otte</obo:IAO_0000117>
        <obo:ICO_0000321 xml:lang="en"></obo:ICO_0000321>
        <rdfs:label xml:lang="en">research method directive</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000274 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000274">
        <rdfs:subClassOf rdf:resource="http://www.ontologyrepository.com/CommonCoreOntologies/DescriptiveInformationContentEntity"/>
        <obo:IAO_0000115 xml:lang="en">A descriptive information content entity that describes the conditions under which compensation is due to some agent.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">J. Neil Otte and Cooper Stansbury</obo:IAO_0000117>
        <obo:ICO_0000321 xml:lang="en"></obo:ICO_0000321>
        <rdfs:label xml:lang="en">description of conditional compensation</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000275 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000275">
        <rdfs:subClassOf rdf:resource="http://www.ontologyrepository.com/CommonCoreOntologies/DescriptiveInformationContentEntity"/>
        <obo:IAO_0000115 xml:lang="en">A descriptive information content entity that describes an emotional state of mental or physical uneasiness.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury and J. Neil Otte</obo:IAO_0000117>
        <obo:ICO_0000321 xml:lang="en"></obo:ICO_0000321>
        <rdfs:label xml:lang="en">description of discomfort</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000276 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000276">
        <rdfs:subClassOf rdf:resource="http://www.ontologyrepository.com/CommonCoreOntologies/DescriptiveInformationContentEntity"/>
        <obo:IAO_0000115 xml:lang="en">A descriptive information content entity that describes biospecimens that have been collected.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">J. Neil Otte, Cooper Stansbury, Jonathan Vajda</obo:IAO_0000117>
        <obo:ICO_0000321 xml:lang="en"></obo:ICO_0000321>
        <rdfs:label xml:lang="en">description of collected biospecimens</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000277 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000277">
        <rdfs:subClassOf rdf:resource="http://www.ontologyrepository.com/CommonCoreOntologies/DescriptiveInformationContentEntity"/>
        <obo:IAO_0000115 xml:lang="en">A descriptive information content entity that describes information that may be collected or the processes of information collection.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury</obo:IAO_0000117>
        <obo:ICO_0000321 xml:lang="en"></obo:ICO_0000321>
        <rdfs:label xml:lang="en">description of collected information</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000278 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000278">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000305"/>
        <obo:IAO_0000115 xml:lang="en">A descriptive information content entity that describes how biospecimens will be used.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Jonathan Vajda</obo:IAO_0000117>
        <obo:ICO_0000321 xml:lang="en"></obo:ICO_0000321>
        <rdfs:label xml:lang="en">description of future biospecimen use</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000279 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000279">
        <rdfs:subClassOf rdf:resource="http://www.ontologyrepository.com/CommonCoreOntologies/DescriptiveInformationContentEntity"/>
        <obo:IAO_0000115 xml:lang="en">A descriptive information content entity that describes some procedure for obtaining information only available at some future time.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury and J. Neil Otte</obo:IAO_0000117>
        <obo:ICO_0000321 xml:lang="en"></obo:ICO_0000321>
        <rdfs:label xml:lang="en">description of procedure for obtaining further information</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000280 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000280">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000033"/>
        <obo:IAO_0000112 xml:lang="en">For instance, a patient may assert a preferred mode of communication for contact in the future. This may be given in terms of permitting a communication via email, phone call, etc. and it may mention the address or number to be used.</obo:IAO_0000112>
        <obo:IAO_0000115 xml:lang="en">A directive information entity that prescribes methods for contacting an agent.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">J. Neil Otte, Cooper Stansbury, Jonathan Vajda</obo:IAO_0000117>
        <obo:ICO_0000321 xml:lang="en"></obo:ICO_0000321>
        <rdfs:label xml:lang="en">contact method directive</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000281 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000281">
        <rdfs:subClassOf rdf:resource="http://www.ontologyrepository.com/CommonCoreOntologies/DescriptiveInformationContentEntity"/>
        <obo:IAO_0000117 xml:lang="en">J. Neil Otte and Cooper Stansbury</obo:IAO_0000117>
        <obo:IAO_0000232 xml:lang="en">A descriptive information content entity that describes some conditions that constitute unauthorized disclosure of information.</obo:IAO_0000232>
        <obo:IAO_0000232 xml:lang="en">It is possible that classes like this will be useful in conjuction with descriptions of risk as in: &apos;description of risk of breach of confidentiality.&apos;</obo:IAO_0000232>
        <obo:ICO_0000321 xml:lang="en"></obo:ICO_0000321>
        <rdfs:label xml:lang="en">description of breach of confidentiality</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000282 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000282">
        <rdfs:subClassOf rdf:resource="http://www.ontologyrepository.com/CommonCoreOntologies/DescriptiveInformationContentEntity"/>
        <obo:IAO_0000115 xml:lang="en">A descriptive information content entity that describes legal responsibility that an entity has due to some risk.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Jonathan Vajda, Cooper Stansbury, J. Neil Otte</obo:IAO_0000117>
        <obo:IAO_0000118 xml:lang="en">description of liability</obo:IAO_0000118>
        <obo:ICO_0000321 xml:lang="en"></obo:ICO_0000321>
        <rdfs:label xml:lang="en">description of legal responsibility</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000283 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000283">
        <rdfs:subClassOf rdf:resource="http://www.ontologyrepository.com/CommonCoreOntologies/DescriptiveInformationContentEntity"/>
        <obo:IAO_0000115 xml:lang="en">A description of risk that describes the magnitude of potential financial loss.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury and J. Neil Otte</obo:IAO_0000117>
        <obo:ICO_0000321 xml:lang="en"></obo:ICO_0000321>
        <rdfs:label xml:lang="en">description of financial risk</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000284 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000284">
        <rdfs:subClassOf rdf:resource="http://www.ontologyrepository.com/CommonCoreOntologies/DescriptiveInformationContentEntity"/>
        <obo:IAO_0000115 xml:lang="en">A description of risk that describes the magnitude or probability of damage to the reputation of an agent in a social context.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury and J. Neil Otte</obo:IAO_0000117>
        <obo:ICO_0000321 xml:lang="en"></obo:ICO_0000321>
        <rdfs:label xml:lang="en">description of reputational risk</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000285 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000285">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
        <obo:IAO_0000112 xml:lang="en">E.g., &quot;There are several definitions available for the term &apos;vulnerable population&apos;, the words simply imply the disadvantaged sub-segment of the community requiring utmost care, specific ancillary considerations and augmented protections in research. The vulnerable individuals’ freedom and capability to protect one-self from intended or inherent risks is variably abbreviated, from decreased freewill to inability to make informed choices.&quot;

Preethi Shivayogi (2013). Vulnerable population and methods for their safeguard. Perspectives in clinical research, 4(1), 53-7.</obo:IAO_0000112>
        <obo:IAO_0000115 xml:lang="en">A role that inheres in an agent or group of agents that is the output of a process during which the agent or group of agents is designated as belonging to a vulnerable group.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">J. Neil Otte and Cooper Stansbury</obo:IAO_0000117>
        <obo:IAO_0000232 xml:lang="en">Note: It is possible to belong to a vulnerable population and yet not bear a disposition of vulnerability. Typically, when a person is held to be a vulnerable individual, this is a designation that applies by fiat in virtue of their membership to some legally designated group, and not based on a clear investigation of their individual case. Hence, it seems prudent here to use roles for this purpose.</obo:IAO_0000232>
        <obo:ICO_0000321 xml:lang="en"></obo:ICO_0000321>
        <rdfs:label xml:lang="en">vulnerable individual role</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000286 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000286">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
        <obo:IAO_0000115 xml:lang="en">A role that inheres in a regulatory body that, if realized, is realized in some act of regulatory supervision.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury</obo:IAO_0000117>
        <obo:ICO_0000321 xml:lang="en"></obo:ICO_0000321>
        <rdfs:label xml:lang="en">regulatory oversight role</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000287 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000287">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
        <obo:IAO_0000115 xml:lang="en">A role inhering in a Homo sapiens that, if realized, is realized within the organizational context of a legal jurisdiction, when the bearer fails to meet the legal threshold for adulthood.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury and J. Neil Otte</obo:IAO_0000117>
        <obo:IAO_0000232 xml:lang="en">It is possible to create further defined classes here, such as &apos;abused minor role&apos; that is a minor that participated in a process of abuse.</obo:IAO_0000232>
        <obo:ICO_0000321 xml:lang="en"></obo:ICO_0000321>
        <rdfs:label xml:lang="en">minor role</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000288 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000288">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000030"/>
        <obo:IAO_0000115 xml:lang="en">A woman who is pregnant.</obo:IAO_0000115>
        <obo:IAO_0000232 xml:lang="en">Could reuse: http://purl.obolibrary.org/obo/ontoneo/ONTONEO_00000197</obo:IAO_0000232>
        <obo:ICO_0000321 xml:lang="en"></obo:ICO_0000321>
        <rdfs:label xml:lang="en">pregnant woman</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000289 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000289">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
        <obo:IAO_0000115 xml:lang="en">A role inhering in a Homo sapiens that is realized in a process of incarceration.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Jonathan Vajda</obo:IAO_0000117>
        <obo:IAO_0000232 xml:lang="en">Note from Jonathan Vajda: Depending on the level of granluarity, we could have prisoner role, incarcerated role, etc. and these roles would differentiated by what kind of stasis of incarceration necessary.</obo:IAO_0000232>
        <obo:ICO_0000321 xml:lang="en"></obo:ICO_0000321>
        <rdfs:label xml:lang="en">prisoner role</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000290 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000290">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000310"/>
        <obo:IAO_0000115 xml:lang="en">A document designed for the purpose of assisting in an act of waiving, and which contains both some description of waiver and some waiver directive.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury and J. Neil Otte</obo:IAO_0000117>
        <obo:ICO_0000321 xml:lang="en"></obo:ICO_0000321>
        <rdfs:label xml:lang="en">waiver document</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000291 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000291">
        <rdfs:subClassOf rdf:resource="http://www.ontologyrepository.com/CommonCoreOntologies/DescriptiveInformationContentEntity"/>
        <obo:IAO_0000115 xml:lang="en">A descriptive information content entity that describes an entity that provides positive motivation for some material entity.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury and J. Neil Otte</obo:IAO_0000117>
        <obo:IAO_0000232 xml:lang="en">From NCI Thesaurus OBO Edition: Incentive: A benefit, consideration, or positive motivational influence, financial or otherwise, given to induce a specific action. [def-source: NCI]</obo:IAO_0000232>
        <obo:ICO_0000321 xml:lang="en"></obo:ICO_0000321>
        <rdfs:label xml:lang="en">description of incentive</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000292 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000292">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000272"/>
        <obo:IAO_0000115 xml:lang="en">A protocol that is formal plan of a research activity, including the objective, rationale, design, materials, and methods for the conduct of the activity.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury and J. Neil Otte</obo:IAO_0000117>
        <obo:IAO_0000232 xml:lang="en">This term was adapted from: http://purl.obolibrary.org/obo/NCIT_C70817</obo:IAO_0000232>
        <rdfs:label xml:lang="en">study protocol</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000293 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000293">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000033"/>
        <obo:IAO_0000115 xml:lang="en">A directive information entity that prescribes the information that is permitted to be shared or the processes for sharing that information.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury</obo:IAO_0000117>
        <obo:ICO_0000321 xml:lang="en"></obo:ICO_0000321>
        <rdfs:label xml:lang="en">data sharing directive</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000294 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000294">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000033"/>
        <obo:IAO_0000115 xml:lang="en">A directive information entity that prescribes the process of transferring a permission role from one bearer to another.</obo:IAO_0000115>
        <obo:IAO_0000116 xml:lang="en">Note: Strictly speaking, of course, roles are not transferred; rather, the transfer of a permission involves the role of one agent ceasing to exist, and the role of a second agent coming into existence.</obo:IAO_0000116>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury and J. Neil Otte</obo:IAO_0000117>
        <obo:ICO_0000321 xml:lang="en"></obo:ICO_0000321>
        <rdfs:label xml:lang="en">permission transfer directive</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000295 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000295">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000033"/>
        <obo:IAO_0000115 xml:lang="en">A directive information entity that prescribes the processes that involve some entity as a participant.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury and J. Neil Otte</obo:IAO_0000117>
        <obo:ICO_0000321 xml:lang="en"></obo:ICO_0000321>
        <rdfs:label xml:lang="en">future use directive</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000296 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000296">
        <rdfs:subClassOf rdf:resource="http://www.ontologyrepository.com/CommonCoreOntologies/DescriptiveInformationContentEntity"/>
        <obo:IAO_0000115 xml:lang="en">A descriptive information content entity that describes the negative impact or harm that may befall an agent who withdraws from an investigation.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Jonathan Vajda</obo:IAO_0000117>
        <obo:ICO_0000321 xml:lang="en"></obo:ICO_0000321>
        <rdfs:label xml:lang="en">description of consequences of voluntarily withdrawal</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000297 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000297">
        <rdfs:subClassOf rdf:resource="http://www.ontologyrepository.com/CommonCoreOntologies/StasisOfGenericallyDependentContinuant"/>
        <obo:IAO_0000115 xml:lang="en">A stasis of generically dependent continuant that has participant some information content entity and during which that information content entity is recognized within that jurisdiction and directs governance within that jurisdiction.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury</obo:IAO_0000117>
        <rdfs:label xml:lang="en">stasis of regulation</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000298 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000298">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000297"/>
        <obo:IAO_0000115 xml:lang="en">A stasis of regulation that has participant some information content entity and during which that information content entity is recognized as a law within the jurisdiction in which the stasis of regulation is occurring.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, J. Neil Otte</obo:IAO_0000117>
        <obo:IAO_0000232 xml:lang="en">The  ‘stasis of law’ designates the spatial and temporal conditions that need to be met in order for a regulatory document to be a ‘law’ or a ‘policy.’ This is necessary because laws, or other regulations are overturned, made obsolete, ect..., but material entities concretizing them persist.</obo:IAO_0000232>
        <obo:IAO_0000232 xml:lang="en">There are many definitions and conceptions of law, which can be elaborated in further work. There is a concern not to define law in such a way that we narrow the scope beyond an international context.</obo:IAO_0000232>
        <rdfs:label xml:lang="en">stasis of law</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000299 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000299">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000252"/>
        <obo:IAO_0000115 xml:lang="en">A trigger condition directive that prescribes conditions for which a individual bears a vulnerability role or disposition of vulnerability, or a population of such individuals.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">J. Neil Otte, Jonathan Vajda, Cooper Stansbury</obo:IAO_0000117>
        <obo:IAO_0000232 xml:lang="en">See http://purl.unep.org/sdg/SDGIO_00000024 (Vulnerability):  A disposition of an entity to undergo undesirable change in response to some exposure.</obo:IAO_0000232>
        <obo:ICO_0000321 xml:lang="en"></obo:ICO_0000321>
        <rdfs:label xml:lang="en">protection directive</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000300 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000300">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
        <obo:IAO_0000115 xml:lang="en">A planned process in which a regulatory body directs or monitors another planned process.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury and J. Neil Otte</obo:IAO_0000117>
        <obo:ICO_0000321 xml:lang="en"></obo:ICO_0000321>
        <rdfs:label xml:lang="en">act of regulatory supervision</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000301 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000301">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000015"/>
        <obo:IAO_0000115 xml:lang="en">A process of mistreating an entity such that the mistreated entity is harmed.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, J. Neil Otte, and Jonathan Vajda</obo:IAO_0000117>
        <obo:IAO_0000119 xml:lang="en">adapted from &quot;abuse.&quot; Merriam-Webster.com. 2011. https://www.merriam-webster.com (30 August 2018).</obo:IAO_0000119>
        <obo:ICO_0000321 xml:lang="en"></obo:ICO_0000321>
        <rdfs:label xml:lang="en">act of abuse</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000302 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000302">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000269"/>
        <obo:IAO_0000115 xml:lang="en">An act of communicating in which information is shared, overriding or violating a judgment that the information should not be shared.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">J. Neil Otte and Cooper Stansbury</obo:IAO_0000117>
        <obo:IAO_0000232 xml:lang="en">It is possible that there are meaningful defined classes here like: &apos;act of authorized disclosure&apos; and &apos;act of unauthorized disclosure.&apos;</obo:IAO_0000232>
        <obo:ICO_0000321 xml:lang="en"></obo:ICO_0000321>
        <rdfs:label xml:lang="en">act of disclosure</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000303 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000303">
        <rdfs:subClassOf rdf:resource="http://www.ontologyrepository.com/CommonCoreOntologies/DescriptiveInformationContentEntity"/>
        <obo:IAO_0000115 xml:lang="en">A descriptive information content entity that describes a research procedure.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury</obo:IAO_0000117>
        <obo:ICO_0000321 xml:lang="en"></obo:ICO_0000321>
        <rdfs:label xml:lang="en">description of research procedure</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000304 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000304">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000305"/>
        <obo:IAO_0000115 xml:lang="en">A descriptive information content entity that describes how data will be used.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Jonathan Vajda</obo:IAO_0000117>
        <obo:ICO_0000321 xml:lang="en"></obo:ICO_0000321>
        <rdfs:label xml:lang="en">description of future data use</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000305 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000305">
        <rdfs:subClassOf rdf:resource="http://www.ontologyrepository.com/CommonCoreOntologies/DescriptiveInformationContentEntity"/>
        <obo:IAO_0000115 xml:lang="en">A descriptive information content entity that describes future use of material or information.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury</obo:IAO_0000117>
        <obo:ICO_0000321 xml:lang="en"></obo:ICO_0000321>
        <rdfs:label xml:lang="en">description of future use</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000306 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000306">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0021003"/>
        <obo:IAO_0000115 xml:lang="en">A social act of relinquishing a right, claim, or privilege.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Jonathan Vajda</obo:IAO_0000117>
        <obo:IAO_0000119 xml:lang="en">&quot;waiver.&quot; Merriam-Webster.com. 2011. https://www.merriam-webster.com (30 August 2018).</obo:IAO_0000119>
        <obo:ICO_0000321 xml:lang="en"></obo:ICO_0000321>
        <rdfs:label xml:lang="en">act of waiving</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000307 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000307">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000033"/>
        <obo:IAO_0000115 xml:lang="en">A directive information entity that prescribes an act of waiving.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury</obo:IAO_0000117>
        <obo:ICO_0000321 xml:lang="en"></obo:ICO_0000321>
        <rdfs:label xml:lang="en">waiver directive</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000308 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000308">
        <rdfs:subClassOf rdf:resource="http://www.ontologyrepository.com/CommonCoreOntologies/DescriptiveInformationContentEntity"/>
        <obo:IAO_0000115 xml:lang="en">A descriptive information content entity that describes a directive information content entity that can be ignored.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury</obo:IAO_0000117>
        <obo:IAO_0000232 xml:lang="en">adapted from: http://purl.obolibrary.org/obo/NCIT_C113777</obo:IAO_0000232>
        <obo:ICO_0000321 xml:lang="en"></obo:ICO_0000321>
        <rdfs:label xml:lang="en">description of waiver</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000309 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000309">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
        <obo:IAO_0000115 xml:lang="en">A role inhering in a Homo sapiens that, if realized, is realized in being a passive participant in some act of abuse process.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Jonathan Vajda</obo:IAO_0000117>
        <obo:IAO_0000600 xml:lang="en">A passive participant in such a process would mean that the act of abuse has this entity as its target; i.e., the bearer of this role is entity that is mistreated.</obo:IAO_0000600>
        <obo:ICO_0000321 xml:lang="en"></obo:ICO_0000321>
        <rdfs:label xml:lang="en">abused person role</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000310 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000310">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000033"/>
        <obo:IAO_0000115 xml:lang="en">A directive information entity that prescribes some investigation of biospecimens.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">J. Neil Otte</obo:IAO_0000117>
        <obo:ICO_0000321 xml:lang="en"></obo:ICO_0000321>
        <rdfs:label xml:lang="en">directive about research of biospecimens</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000311 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000311">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
        <obo:IAO_0000115 xml:lang="en">A planned process that involves the investigation of some sequence of DNA.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">J. Neil Otte</obo:IAO_0000117>
        <obo:ICO_0000321 xml:lang="en"></obo:ICO_0000321>
        <rdfs:label xml:lang="en">act of genetic testing</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000312 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000312">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000033"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://www.ontologyrepository.com/CommonCoreOntologies/prescribes"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/ICO_0000311"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <obo:IAO_0000115 xml:lang="en">A directive information entity that prescribes some act of genetic testing.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">J. Neil Otte</obo:IAO_0000117>
        <obo:ICO_0000321 xml:lang="en"></obo:ICO_0000321>
        <rdfs:label xml:lang="en">genetic testing directive</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000313 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000313">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
        <obo:IAO_0000115 xml:lang="en">A role inhering in some material entity that is realized in an act of artifact modification where the material entity is separated from another portion of material.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">J. Neil Otte, Elizabeth Umberfield</obo:IAO_0000117>
        <obo:ICO_0000321 xml:lang="en"></obo:ICO_0000321>
        <rdfs:label xml:lang="en">excess material role</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000314 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000314">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000005"/>
        <obo:IAO_0000115 xml:lang="en">An objective specification whose intended process endpoint is an investigation.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury</obo:IAO_0000117>
        <obo:ICO_0000321 xml:lang="en"></obo:ICO_0000321>
        <rdfs:label xml:lang="en">investigation objective specification</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000315 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000315">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000005"/>
        <obo:IAO_0000115 xml:lang="en">An objective specification that prescribes the participation of an information content entity or a material entity in a process prescirbed by a future invesitgation objective specification.</obo:IAO_0000115>
        <obo:IAO_0000116 xml:lang="en">&quot;The use in research of information or human biological materials originally collected for a purpose other than the current research purpose.&quot;</obo:IAO_0000116>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury</obo:IAO_0000117>
        <obo:IAO_0000119 xml:lang="en">Adapted from: “Secondary Use of Data - FAQs - Research Ethics Office - Sunnybrook Research Institute.” [Online]. Available: https://sunnybrook.ca/research/content/?page=sri-crs-reo-faq-secondaryusedata. [Accessed: 07-Nov-2018].</obo:IAO_0000119>
        <obo:ICO_0000321 xml:lang="en"></obo:ICO_0000321>
        <rdfs:label xml:lang="en">secondary use objective specification</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000316 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000316">
        <owl:equivalentClass>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://www.ontologyrepository.com/CommonCoreOntologies/prescribes"/>
                <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
            </owl:Restriction>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000033"/>
        <obo:IAO_0000115 xml:lang="en">A directive information entity that prescribes some role.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury</obo:IAO_0000117>
        <obo:ICO_0000321 xml:lang="en"></obo:ICO_0000321>
        <rdfs:label xml:lang="en">role directive</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000317 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000317">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000316"/>
        <obo:IAO_0000115 xml:lang="en">A role directive that prescribes the bearer of a patient role in a process.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury</obo:IAO_0000117>
        <obo:ICO_0000321 xml:lang="en"></obo:ICO_0000321>
        <rdfs:label xml:lang="en">patient role directive</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000318 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000318">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000316"/>
        <obo:IAO_0000115 xml:lang="en">A role directive that prescirbes the bearer of a regulatory oversight role in a process.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury</obo:IAO_0000117>
        <obo:ICO_0000321 xml:lang="en"></obo:ICO_0000321>
        <rdfs:label xml:lang="en">regulatory oversight role directive</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000319 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000319">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000316"/>
        <obo:IAO_0000115 xml:lang="en">A role directive that prescribes the bearer of an investigator role in a process.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury</obo:IAO_0000117>
        <obo:ICO_0000321 xml:lang="en"></obo:ICO_0000321>
        <rdfs:label xml:lang="en">investigator role directive</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000320 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000320">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000316"/>
        <obo:IAO_0000115 xml:lang="en">A role directive that prescribes the bearer of a legally authorized representative role in process.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury</obo:IAO_0000117>
        <obo:ICO_0000321 xml:lang="en"></obo:ICO_0000321>
        <rdfs:label xml:lang="en">legally authorized representative role directive</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000322 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000322">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000244"/>
        <obo:IAO_0000115 xml:lang="en">A &apos;permission directive&apos; that prescribes some action that is made allowable by a consenting entity.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield, Kathleen Ford, Marcy Harris</obo:IAO_0000117>
        <obo:ICO_0000404 xml:lang="en"></obo:ICO_0000404>
        <rdfs:comment xml:lang="en">(1) We indend instances of &apos;consent directive&apos; to be stated positively with repect to the act of permitting. A &apos;consent directive&apos; may only allow for different actions, not forbid them. However, since &apos;consent directives&apos; may simultaneously create new duties or obligations, we define &apos;designated consent condition&apos; in order to help manage these nested deontic statements. 

(2) Another, less formal definition: &apos;A statement that guides action that is made allowable by a consenting entity, where that action is otherwise impermissible.&apos;

(3) The definition from HL7: &quot;The legal record of a healthcare consumer&apos;s agreement with a party responsible for enforcing the consumer’s choices, which permits or denies identified actors or roles to perform actions affecting the consumer within a given context for specific purposes and periods of time.&quot; https://www.hl7.org/fhir/consent.html</rdfs:comment>
        <rdfs:label xml:lang="en">consent directive</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000323 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000323">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000244"/>
        <obo:IAO_0000115 xml:lang="en">A &apos;permission directive&apos; that prescribes some action that is made allowable by an assenting entity.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield, Kathleen Ford, Marcy Harris</obo:IAO_0000117>
        <obo:ICO_0000404 xml:lang="en"></obo:ICO_0000404>
        <rdfs:comment xml:lang="en">(1) We indend instances of &apos;assent directive&apos; to be stated positively with repect to the act of permitting. A &apos;assent directive&apos; may only allow for different actions, not forbid them. However, since &apos;assent directives&apos; may simultaneously create new duties or obligations, we define &apos;designated consent condition&apos; in order to help manage these nested deontic statements.</rdfs:comment>
        <rdfs:label xml:lang="en">assent directive</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000324 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000324">
        <rdfs:subClassOf rdf:resource="http://www.ontologyrepository.com/CommonCoreOntologies/DesignativeInformationContentEntity"/>
        <obo:IAO_0000115 xml:lang="en">A &apos;Directive Information Content Entity&apos; that designates a process as permissable.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield, Kathleen Ford, Marcy Harris</obo:IAO_0000117>
        <obo:ICO_0000404 xml:lang="en"></obo:ICO_0000404>
        <rdfs:comment xml:lang="en">(1) It is critical that these classes not be mistaken for processes themselves. If you intend to build logical axioms within the BFO framework it will be necessary to create realtions between instances of &apos;designated actions&apos; and &apos;processes.&apos; We leave this mapping undone in order to accomodate various non-BFO process value sets. 

(2) We believe it is important to separate &apos;processes&apos; from their inputs, outputs, or participants in action designatation. For example: instead of a &apos;designated process of blood extraction&apos; we would advocate for creation of a designated action such as &apos;designated process of extraction&apos; so that this class may also be used with different objects, like teeth. This is of course, application dependent. This is only a guide.

(3) It is our intent that all instances of &apos;designated actions&apos; that are related to instances of &apos;permission directive&apos; be processes or events in which deontic roles of some kind may be realized. Stated another way, a &apos;designated action&apos; should be an action that is not allowable unless a process makes it so: for example, a &apos;process of informed consent&apos; with a subprocess &apos;act of permitting.&apos;</rdfs:comment>
        <rdfs:label xml:lang="en">designated action</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000325 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000325">
        <rdfs:subClassOf rdf:resource="http://www.ontologyrepository.com/CommonCoreOntologies/DesignativeInformationContentEntity"/>
        <obo:IAO_0000115 xml:lang="en">A &apos;Designative Information Content Entity&apos; that designates an entity which can bear deontic roles.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield, Kathleen Ford, Marcy Harris</obo:IAO_0000117>
        <obo:ICO_0000404 xml:lang="en"></obo:ICO_0000404>
        <rdfs:comment xml:lang="en">(1) In the general sense, &apos;designated actors&apos; should designate entities which perform, or participate in an action. While the notion of &apos;agency&apos; is important for some entiites, at some times, involved in processes of informed consent, we do not define actors in terms of their agency.

(2) Within the greater BFO, D-acts, and ICO frameworks, we believe that a &apos;designated actor&apos; has some capability to bear deontic roles.</rdfs:comment>
        <rdfs:label xml:lang="en">designated actor</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000326 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000326">
        <rdfs:subClassOf rdf:resource="http://www.ontologyrepository.com/CommonCoreOntologies/DesignativeInformationContentEntity"/>
        <obo:IAO_0000115 xml:lang="en">A &apos;Designative Information Content Entity&apos; that designates the object of a &apos;designated action&apos;.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield, Kathleen Ford, Marcy Harris</obo:IAO_0000117>
        <obo:ICO_0000404 xml:lang="en"></obo:ICO_0000404>
        <rdfs:comment xml:lang="en">(1) In English, this is typically the &apos;object&apos; of the clause where the &apos;designated action&apos; is the verb. We may also refer to this as the &apos;designated target&apos; of the action. However, we choose &apos;object&apos; to more clearly separate the objects of the actions from the ends.</rdfs:comment>
        <rdfs:label xml:lang="en">designated object</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000327 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000327">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000033"/>
        <obo:IAO_0000115 xml:lang="en">A &apos;directive information entity&apos; that directs the conditions of &apos;allowability&apos; for a &apos;consent directive&apos;.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield, Kathleen Ford, Marcy Harris</obo:IAO_0000117>
        <obo:ICO_0000404 xml:lang="en"></obo:ICO_0000404>
        <rdfs:comment xml:lang="en">(1) A &apos;designated consent condition&apos; defines or delimits the scope, boundaries, requirements, attributes, antecendents, or limitations the &apos;designated action&apos; which may be permitted.  As such, it is specifically tied to  permissions to avoid complex nested impertives as much as possible. The central question to ask is: &apos;what does permission to undertake this action depend on?&apos;

(2) Our intent is to focus on conditionals related to &apos;obtaining permission&apos; rather than all possible conditionals.</rdfs:comment>
        <rdfs:label xml:lang="en">permission condition directive</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000328 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000328">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000357"/>
        <obo:IAO_0000115 xml:lang="en">A &apos;permission condition directive&apos; that directs the purpose for a &apos;permission directive&apos;.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield, Kathleen Ford, Marcy Harris</obo:IAO_0000117>
        <obo:ICO_0000404 xml:lang="en"></obo:ICO_0000404>
        <obo:ICO_0000420 xml:lang="en">purpose: https://www.merriam-webster.com/dictionary/purpose

(1) to propose as an aim to oneself

&apos;means to an end&apos;: https://www.merriam-webster.com/dictionary/a%20means%20to%20an%20end

(1) something done only to produce a desired result</obo:ICO_0000420>
        <rdfs:comment xml:lang="en">(1) We refer to &apos;designated purpose&apos; as the specific end, outcome, or target of some designated action. We note that this necessarily involves the notion of &apos;intentionality.&apos; Because this may be regarded as problematic in a realist ontology, please tread with caution.</rdfs:comment>
        <rdfs:label xml:lang="en">permission purpose directive</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000329 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000329">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000324"/>
        <obo:IAO_0000115 xml:lang="en">A &apos;designated action&apos; that designates a process of access as permissable.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield, Kathleen Ford, Marcy Harris</obo:IAO_0000117>
        <obo:ICO_0000404 xml:lang="en"></obo:ICO_0000404>
        <obo:ICO_0000420 xml:lang="en">access: https://www.merriam-webster.com/dictionary/access

(1) to get at
(2) to gain access to
(3) to be able to use, enter, or get near (something)
(4) to open or load (a computer file, an Internet site, etc.)
(5) permission, liberty, or ability to enter, approach, or pass to and from a place or to approach or communicate with a person or thing
(6) freedom or ability to obtain or make use of something</obo:ICO_0000420>
        <rdfs:comment xml:lang="en">(1) Access is a complex issue. We intend this class to cover instances whereby an entity may gain the ability to act upon an object whereby they previously were not able to do so. Examples may include: accessing PHI in a database, linking sensitive information to a biospecimen repository, ect.</rdfs:comment>
        <rdfs:label xml:lang="en">designated process of access</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000330 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000330">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000324"/>
        <obo:IAO_0000115 xml:lang="en">A &apos;designated action&apos; that designates a process of analysis as permissable.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield, Kathleen Ford, Marcy Harris</obo:IAO_0000117>
        <obo:ICO_0000404 xml:lang="en"></obo:ICO_0000404>
        <obo:ICO_0000420 xml:lang="en">analyze: https://www.merriam-webster.com/dictionary/collect

(1) to study or determine the nature and relationship of the parts of (something) by analysis</obo:ICO_0000420>
        <rdfs:label xml:lang="en">designated process of analysis</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000331 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000331">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000324"/>
        <obo:IAO_0000115 xml:lang="en">A &apos;designated action&apos; that designates a procedure as permissable.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield, Kathleen Ford, Marcy Harris</obo:IAO_0000117>
        <obo:ICO_0000404 xml:lang="en"></obo:ICO_0000404>
        <rdfs:comment xml:lang="en">(1) It is our intent for this term to serve as a blanket class for all types of clinical procedures. If an application demands specificity of procedures, for example administration of anesthetic, this would be a good parent class for such a list or subtree of procedures.</rdfs:comment>
        <rdfs:label xml:lang="en">designated procedure</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000332 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000332">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000324"/>
        <obo:IAO_0000115 xml:lang="en">A &apos;designated action&apos; that designates a process of collection as permissable.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield, Kathleen Ford, Marcy Harris</obo:IAO_0000117>
        <obo:ICO_0000404 xml:lang="en"></obo:ICO_0000404>
        <obo:ICO_0000420 xml:lang="en">collect: https://www.merriam-webster.com/dictionary/collect

(1) to bring together into one body or place
(2) to gather or exact from a number of persons or sources
(3) to gain or regain control of</obo:ICO_0000420>
        <rdfs:comment xml:lang="en">(1) It is our intent that this class includes instances of collection of material and of information. We note that the actual processes of &apos;retention&apos; (read: &apos;storage&apos;) and &apos;collection&apos; may be ambigously differentiated.  

(2) We intend this class to primarily cover de novo collection.</rdfs:comment>
        <rdfs:label xml:lang="en">designated process of collection</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000333 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000333">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000324"/>
        <obo:IAO_0000115 xml:lang="en">A &apos;designated action&apos; that designates a process of destruction as permissable.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield, Kathleen Ford, Marcy Harris</obo:IAO_0000117>
        <obo:ICO_0000404 xml:lang="en"></obo:ICO_0000404>
        <obo:ICO_0000420 xml:lang="en">destroy: https://www.merriam-webster.com/dictionary/destroy

(1) to put out of existence</obo:ICO_0000420>
        <rdfs:label xml:lang="en">designated process of destruction</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000334 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000334">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000324"/>
        <obo:IAO_0000115 xml:lang="en">A &apos;designated action&apos; that designates a process of disclosure as permissable.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield, Kathleen Ford, Marcy Harris</obo:IAO_0000117>
        <obo:ICO_0000404 xml:lang="en"></obo:ICO_0000404>
        <obo:ICO_0000420 xml:lang="en">disclose: https://www.merriam-webster.com/dictionary/disclose

(1) to make known or public
(2) to expose to view</obo:ICO_0000420>
        <rdfs:label xml:lang="en">designated process of disclosure</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000335 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000335">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000324"/>
        <obo:IAO_0000115 xml:lang="en">A &apos;designated action&apos; that designates a process of duplication as permissable.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield, Kathleen Ford, Marcy Harris</obo:IAO_0000117>
        <obo:ICO_0000404 xml:lang="en"></obo:ICO_0000404>
        <obo:ICO_0000420 xml:lang="en">duplicate: https://www.merriam-webster.com/dictionary/duplicate

(1) to make double or twofold
(2) to make a copy of</obo:ICO_0000420>
        <rdfs:comment xml:lang="en">(1) We intend this designation to include processes of &apos;copying.&apos;</rdfs:comment>
        <rdfs:label xml:lang="en">designated process of duplication</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000336 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000336">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000324"/>
        <obo:IAO_0000115 xml:lang="en">A &apos;designated action&apos; that designates a process unspecified use as permissable.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield, Kathleen Ford, Marcy Harris</obo:IAO_0000117>
        <obo:ICO_0000404 xml:lang="en"></obo:ICO_0000404>
        <obo:ICO_0000420 xml:lang="en">&apos;use&apos;

(1) to put into action or service
(2) to carry out a purpose or action by means of</obo:ICO_0000420>
        <obo:ICO_0000420 xml:lang="en">unspecified: https://www.merriam-webster.com/dictionary/unspecified

(1) not named or stated explicitly</obo:ICO_0000420>
        <rdfs:comment xml:lang="en">(1) this is a &apos;catch-all&apos; bucket to define those &apos;designated action&apos;(s) that are not explicit.

(2) does this require a &apos;designated purpose&apos; specification? (this is boarderline rule enforcement that may be appropriate at implmentation, but not here).</rdfs:comment>
        <rdfs:label xml:lang="en">designated process of unspecified use</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000337 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000337">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000324"/>
        <obo:IAO_0000115 xml:lang="en">A &apos;designated action&apos; that designates a process of modifcation as permissable.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield, Kathleen Ford, Marcy Harris</obo:IAO_0000117>
        <obo:ICO_0000404 xml:lang="en"></obo:ICO_0000404>
        <obo:ICO_0000420 xml:lang="en">modify: https://www.merriam-webster.com/dictionary/modify

(1) to make basic or fundamental changes in often to give a new orientation to or to serve a new end</obo:ICO_0000420>
        <rdfs:label xml:lang="en">designated process of modification</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000338 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000338">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000324"/>
        <obo:IAO_0000115 xml:lang="en">A &apos;designated action&apos; that designates a process of contact permissable.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield, Kathleen Ford, Marcy Harris</obo:IAO_0000117>
        <obo:ICO_0000404 xml:lang="en"></obo:ICO_0000404>
        <rdfs:comment xml:lang="en">(1) This includes instances of recontact.</rdfs:comment>
        <rdfs:label xml:lang="en">designated process of contact</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000339 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000339">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000324"/>
        <obo:IAO_0000115 xml:lang="en">A &apos;designated action&apos; that designates a process of retention as permissable.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield, Kathleen Ford, Marcy Harris</obo:IAO_0000117>
        <obo:ICO_0000404 xml:lang="en"></obo:ICO_0000404>
        <obo:ICO_0000420 xml:lang="en">retain: https://www.merriam-webster.com/dictionary/retain

(1) to keep in possession or use
(2) to keep in one&apos;s pay or service
(3) to hold secure or intact</obo:ICO_0000420>
        <rdfs:comment xml:lang="en">(1) these may often be accompanied by a &apos;designated temporal conditon&apos;.

(2) if these are do not follow (1), they may be more approproately labeled &apos;stases&apos; instead of &apos;process.&apos;

(3) we believe this includes storage, should it be re-labeled &apos;storage?&apos;</rdfs:comment>
        <rdfs:label xml:lang="en">designated process of retention</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000340 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000340">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000324"/>
        <obo:IAO_0000115 xml:lang="en">A &apos;designated action&apos; that designates a process of sharing permissable.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield, Kathleen Ford, Marcy Harris</obo:IAO_0000117>
        <obo:ICO_0000404 xml:lang="en"></obo:ICO_0000404>
        <obo:ICO_0000420 xml:lang="en">share: https://www.merriam-webster.com/dictionary/share

(1) to partake of, use, experience, occupy, or enjoy with others</obo:ICO_0000420>
        <rdfs:comment xml:lang="en">(1) this, along with &apos;transfer&apos; need to be properly fleshed out. Perhaps the difference is &apos;ownership.&apos; When you share, you may retain the right to ownership, but when you transfer, you yield this right....

(2) does sharing including publishing PHI? De-anonymizing?

(3) what about &apos;release?&apos;</rdfs:comment>
        <rdfs:label xml:lang="en">designated process of sharing</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000341 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000341">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000324"/>
        <obo:IAO_0000115 xml:lang="en">A &apos;designated action&apos; that designates a process of study as permissable.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield, Kathleen Ford, Marcy Harris</obo:IAO_0000117>
        <obo:ICO_0000404 xml:lang="en"></obo:ICO_0000404>
        <rdfs:comment xml:lang="en">(1) require link to a &apos;Descriptive Information Content Entity&apos; like: &apos;STUDY DETAILS?&apos;

(2) STUDY PRTICIPATION</rdfs:comment>
        <rdfs:label xml:lang="en">designated process of study</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000342 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000342">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000324"/>
        <obo:IAO_0000115 xml:lang="en">A &apos;designated action&apos; that designates a process of surveillance.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield, Kathleen Ford, Marcy Harris</obo:IAO_0000117>
        <obo:ICO_0000404 xml:lang="en"></obo:ICO_0000404>
        <obo:ICO_0000420 xml:lang="en">surveil: https://www.merriam-webster.com/dictionary/surveil

(1) to subject to surveillance</obo:ICO_0000420>
        <rdfs:comment xml:lang="en">(1) our usage more closely resembles the use in NCIT.</rdfs:comment>
        <rdfs:label>designated process of surveillance</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000343 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000343">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000324"/>
        <obo:IAO_0000115 xml:lang="en">A &apos;designated action&apos; that designates a process of transferral of ownership permissable.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield, Kathleen Ford, Marcy Harris</obo:IAO_0000117>
        <obo:ICO_0000404 xml:lang="en"></obo:ICO_0000404>
        <obo:ICO_0000420 xml:lang="en">transfer: https://www.merriam-webster.com/dictionary/transfer

(1) to convey from one person, place, or situation to another 
(2) to make over the possession or control of
(3) to move to a different place, region, or situation</obo:ICO_0000420>
        <rdfs:comment xml:lang="en">(1) is collection a tranfer of ownership?</rdfs:comment>
        <rdfs:label xml:lang="en">designated process of transfer</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000344 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000344">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000328"/>
        <obo:IAO_0000115 xml:lang="en">A &apos;permission purpose directive&apos; that designates a research process as its end.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield, Kathleen Ford, Marcy Harris</obo:IAO_0000117>
        <obo:ICO_0000404 xml:lang="en"></obo:ICO_0000404>
        <rdfs:comment xml:lang="en">(1) This is a pointer to ADAM Matrix.

(2) covers future</rdfs:comment>
        <rdfs:label xml:lang="en">designated research purpose</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000345 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000345">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000344"/>
        <obo:IAO_0000115 xml:lang="en">A &apos;designated research purpose&apos; that designates a biomedical research process as its end.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield, Kathleen Ford, Marcy Harris</obo:IAO_0000117>
        <rdfs:label xml:lang="en">designated biomedical research purpose</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000346 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000346">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000345"/>
        <obo:IAO_0000115 xml:lang="en">A &apos;designated research purpose&apos; that designates a process of genetic research as its end.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield, Kathleen Ford, Marcy Harris</obo:IAO_0000117>
        <rdfs:label xml:lang="en">designated genetic research purpose</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000347 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000347">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000328"/>
        <obo:IAO_0000115 xml:lang="en">A &apos;permission purpose directive&apos; that designates a process relating to the management of an organization as its end.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield, Kathleen Ford, Marcy Harris</obo:IAO_0000117>
        <obo:ICO_0000404 xml:lang="en"></obo:ICO_0000404>
        <obo:ICO_0000420 xml:lang="en">administrative: https://www.merriam-webster.com/dictionary/administrative

(1) relating to the management of a company, school, or other organization
administrative tasks/duties/responsibilities</obo:ICO_0000420>
        <rdfs:comment xml:lang="en">(1) actions undertaken support system processing</rdfs:comment>
        <rdfs:label xml:lang="en">designated administrative purpose</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000348 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000348">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000328"/>
        <obo:IAO_0000115 xml:lang="en">A &apos;permission purpose directive&apos; that designates a process of diagnosis as its end.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield, Kathleen Ford, Marcy Harris</obo:IAO_0000117>
        <obo:ICO_0000404 xml:lang="en"></obo:ICO_0000404>
        <rdfs:comment xml:lang="en">(1) related to, but perhaps not limited to the following classes in OGMS:

(2) diagnosis (http://purl.obolibrary.org/obo/OGMS_0000073)

(3) diagnostic process (http://purl.obolibrary.org/obo/OGMS_0000104)</rdfs:comment>
        <rdfs:label xml:lang="en">designated diagnostic purpose</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000349 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000349">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000328"/>
        <obo:IAO_0000115 xml:lang="en">A &apos;permission purpose directive&apos;  that designates an educational process as its end.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield, Kathleen Ford, Marcy Harris</obo:IAO_0000117>
        <obo:ICO_0000404 xml:lang="en"></obo:ICO_0000404>
        <rdfs:label xml:lang="en">designated educational purpose</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000350 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000350">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000328"/>
        <obo:IAO_0000115 xml:lang="en">A &apos;permission purpose directive&apos;  that designates a process of evaluation as its end.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield, Kathleen Ford, Marcy Harris</obo:IAO_0000117>
        <obo:ICO_0000404 xml:lang="en"></obo:ICO_0000404>
        <rdfs:label xml:lang="en">designated evaluation purpose</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000351 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000351">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000328"/>
        <owl:disjointWith rdf:resource="http://purl.obolibrary.org/obo/ICO_0000353"/>
        <obo:IAO_0000115 xml:lang="en">A &apos;permission purpose directive&apos; that designates a for-profit activity as its end.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield, Kathleen Ford, Marcy Harris</obo:IAO_0000117>
        <obo:ICO_0000404 xml:lang="en"></obo:ICO_0000404>
        <rdfs:label xml:lang="en">designated commercial purpose</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000352 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000352">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000328"/>
        <obo:IAO_0000115 xml:lang="en">A &apos;permission purpose directive&apos; that designates a healthcare operation process as its end.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield, Kathleen Ford, Marcy Harris</obo:IAO_0000117>
        <obo:ICO_0000404 xml:lang="en"></obo:ICO_0000404>
        <rdfs:comment xml:lang="en">(1) quality and safety purposes</rdfs:comment>
        <rdfs:label xml:lang="en">designated healthcare operation purpose</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000353 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000353">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000328"/>
        <obo:IAO_0000115 xml:lang="en">A &apos;permission purpose directive&apos; that designates a nonprofit activity as its end.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield, Kathleen Ford, Marcy Harris</obo:IAO_0000117>
        <obo:ICO_0000404 xml:lang="en"></obo:ICO_0000404>
        <rdfs:label xml:lang="en">designated non-commercial purpose</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000354 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000354">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000328"/>
        <obo:IAO_0000115 xml:lang="en">A &apos;permission purpose directive&apos; that designates a process related to healing a disease as its end.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield, Kathleen Ford, Marcy Harris</obo:IAO_0000117>
        <obo:ICO_0000404 xml:lang="en"></obo:ICO_0000404>
        <rdfs:label xml:lang="en">designated therapeutic purpose</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000355 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000355">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000328"/>
        <obo:IAO_0000115 xml:lang="en">A &apos;permission purpose directive&apos; that designates an unspecified process as its end.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield, Kathleen Ford, Marcy Harris</obo:IAO_0000117>
        <obo:ICO_0000404 xml:lang="en"></obo:ICO_0000404>
        <rdfs:label xml:lang="en">designated unspecified purpose</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000356 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000356">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000327"/>
        <obo:IAO_0000115 xml:lang="en">A &apos;permission condition directive&apos; which states a preceding event or condition.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield, Kathleen Ford, Marcy Harris</obo:IAO_0000117>
        <obo:ICO_0000404 xml:lang="en"></obo:ICO_0000404>
        <rdfs:comment xml:lang="en">(1) &apos;antecedent&apos;

(2) may need to specific &apos;post-cendents&apos; also.</rdfs:comment>
        <rdfs:label xml:lang="en">permission precondition</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000357 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000357">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000327"/>
        <obo:IAO_0000115 xml:lang="en">A &apos;permission requirement directive&apos; that directs a &apos;permissable&apos; limit of a &apos;consent directive&apos;.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield, Kathleen Ford, Marcy Harris</obo:IAO_0000117>
        <obo:ICO_0000404 xml:lang="en"></obo:ICO_0000404>
        <rdfs:comment xml:lang="en">(1) Restrictions narrow the scope of the &apos;designated action&apos;. They operate on the &apos;allowability&apos; conditionally.

(2) &quot;Allowable IF NOT &lt;&apos;designated restriction&apos;&gt;&quot;

(3) Alternatively: &apos;A LIMIT ON THE SCOPE OF THE ACTION&apos;

(4) up until the point of.

(5) RESTRAINNING</rdfs:comment>
        <rdfs:label xml:lang="en">permission restriction directive</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000359 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000359">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000357"/>
        <obo:IAO_0000115 xml:lang="en">A &apos;permission restriction directive&apos; that designates an actor.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield, Kathleen Ford, Marcy Harris</obo:IAO_0000117>
        <obo:ICO_0000404 xml:lang="en"></obo:ICO_0000404>
        <rdfs:label xml:lang="en">permitted actor restriction directive</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000360 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000360">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000357"/>
        <obo:IAO_0000115 xml:lang="en">A &apos;permission restriction directive&apos; that defines the spatial boundaries of a &apos;designated action&apos;.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield, Kathleen Ford, Marcy Harris</obo:IAO_0000117>
        <obo:ICO_0000404 xml:lang="en"></obo:ICO_0000404>
        <rdfs:comment xml:lang="en">(1) &apos;Jurisdiction&apos; is often defined in two senses: (1) a geopolitical context (BFO site), or (2) a power. We define jurisdiction as a BFO site, identifiable through shared context of other entities, like a country or state border. The term ‘deontic power role’ reflects the sense of ‘power’ sometimes used to describe jurisdiction.</rdfs:comment>
        <rdfs:label xml:lang="en">jurisdiction restriction directive</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000363 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000363">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000357"/>
        <obo:IAO_0000115 xml:lang="en">A &apos;permission restriction directive&apos; that designates the temporal boundaries of the &apos;designated action&apos;.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield, Kathleen Ford, Marcy Harris</obo:IAO_0000117>
        <obo:ICO_0000404 xml:lang="en"></obo:ICO_0000404>
        <rdfs:label xml:lang="en">temporal restriction directive</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000364 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000364">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000327"/>
        <obo:IAO_0000115 xml:lang="en">A &apos;permission condition directive&apos; that states an additional requirement.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield, Kathleen Ford, Marcy Harris</obo:IAO_0000117>
        <obo:ICO_0000404 xml:lang="en"></obo:ICO_0000404>
        <rdfs:comment xml:lang="en">(1) NOTE: this is an imperitive - it is not strictly part of a permission but is inextricably tied to it.

(2) these are obligations that are dependent on a permission (conditioned on a permission)

(3) MUST BE FULLFILLED

(4) allowability is necessarily dependent on this being fulfilled</rdfs:comment>
        <rdfs:label xml:lang="en">permission requirement directive</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000365 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000365">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000327"/>
        <obo:IAO_0000115 xml:lang="en">A &apos;permission condition directive&apos; that directs another &apos;consent directive&apos; as a requirement of a primary &apos;consent directive&apos;.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield, Kathleen Ford, Marcy Harris</obo:IAO_0000117>
        <obo:ICO_0000404 xml:lang="en"></obo:ICO_0000404>
        <rdfs:comment xml:lang="en">(1) This permission is dependent on another permission

(2) a good example of this are data use agreements that must be signed in addition to an informed consent form to allow for PHI data sharingor disclosure.</rdfs:comment>
        <rdfs:label xml:lang="en">permission sub-directive</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000366 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000366">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000364"/>
        <obo:IAO_0000115 xml:lang="en">A &apos;permission requirement directive&apos; that directs the possibility of withdraw.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield, Kathleen Ford, Marcy Harris</obo:IAO_0000117>
        <obo:ICO_0000404 xml:lang="en"></obo:ICO_0000404>
        <rdfs:comment xml:lang="en">(1) typically from &apos;study participation.&apos;</rdfs:comment>
        <rdfs:label xml:lang="en">possibility of withdraw directive</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000367 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000367">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000326"/>
        <obo:IAO_0000115 xml:lang="en">A &apos;designated object&apos; that designates data or information.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield, Kathleen Ford, Marcy Harris</obo:IAO_0000117>
        <obo:ICO_0000404 xml:lang="en"></obo:ICO_0000404>
        <rdfs:comment xml:lang="en">(1) This is really saying that this is information that designates other information content entities (in BFO-speak).</rdfs:comment>
        <rdfs:comment xml:lang="en">See: http://purl.obolibrary.org/obo/IAO_0000030</rdfs:comment>
        <rdfs:label xml:lang="en">designated data</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000368 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000368">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000367"/>
        <obo:IAO_0000115 xml:lang="en">A &apos;designated data&apos; that designates waveform data.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield, Kathleen Ford, Marcy Harris</obo:IAO_0000117>
        <obo:ICO_0000404 xml:lang="en"></obo:ICO_0000404>
        <rdfs:label xml:lang="en">designated waveform data</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000369 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000369">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000367"/>
        <obo:IAO_0000115 xml:lang="en">A &apos;designated data&apos; that designates genetic data.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield, Kathleen Ford, Marcy Harris</obo:IAO_0000117>
        <obo:ICO_0000404 xml:lang="en"></obo:ICO_0000404>
        <rdfs:label xml:lang="en">designated genetic data</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000370 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000370">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000367"/>
        <obo:IAO_0000115 xml:lang="en">A &apos;designated data&apos; that designates data about health.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield, Kathleen Ford, Marcy Harris</obo:IAO_0000117>
        <obo:ICO_0000404 xml:lang="en"></obo:ICO_0000404>
        <rdfs:label xml:lang="en">designated health information</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000371 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000371">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000367"/>
        <obo:IAO_0000115 xml:lang="en">A &apos;designated data&apos; that designates information that may identify an entity.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield, Kathleen Ford, Marcy Harris</obo:IAO_0000117>
        <obo:ICO_0000404 xml:lang="en"></obo:ICO_0000404>
        <rdfs:comment xml:lang="en">(1) How broad is this notion of &apos;entity&apos; here?

(2) NOTE: this not nested under &apos;designated health information&apos; because information does not need to be health information to be identifiable.

(3) HIPAA Identifiers

(4) Includes fully and partially identifiable information.</rdfs:comment>
        <rdfs:label xml:lang="en">designated identifiable information</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000372 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000372">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000367"/>
        <obo:IAO_0000115 xml:lang="en">A &apos;designated data&apos; that designates image data.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield, Kathleen Ford, Marcy Harris</obo:IAO_0000117>
        <obo:ICO_0000404 xml:lang="en"></obo:ICO_0000404>
        <rdfs:label xml:lang="en">designated image data</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000373 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000373">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000367"/>
        <obo:IAO_0000115 xml:lang="en">A &apos;designated data&apos; that designates video data.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield, Kathleen Ford, Marcy Harris</obo:IAO_0000117>
        <obo:ICO_0000404 xml:lang="en"></obo:ICO_0000404>
        <rdfs:label xml:lang="en">designated video data</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000374 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000374">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000326"/>
        <obo:IAO_0000115 xml:lang="en">A &apos;designated object&apos; that designates a person, or part of a person, as the target of a &apos;designated action.&apos;</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield, Kathleen Ford, Marcy Harris</obo:IAO_0000117>
        <obo:ICO_0000404 xml:lang="en"></obo:ICO_0000404>
        <rdfs:comment xml:lang="en">(1) for when the permitting party is the target of the &apos;designated action&apos;

(2) you may operate on my leg

(3) this includes &apos;study participant&apos; as the target of an action. May also include patient.</rdfs:comment>
        <rdfs:label xml:lang="en">designated human object</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000375 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000375">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000326"/>
        <obo:IAO_0000115 xml:lang="en">A &apos;designated object&apos; that designates a biospecimen.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield, Kathleen Ford, Marcy Harris</obo:IAO_0000117>
        <obo:ICO_0000404 xml:lang="en"></obo:ICO_0000404>
        <rdfs:comment xml:lang="en">(1) this should be mapped to robust specimen heirarchies such as: http://purl.obolibrary.org/obo/OBI_0100051</rdfs:comment>
        <rdfs:comment xml:lang="en">A &apos;designated object&apos; that designates a specimen.</rdfs:comment>
        <rdfs:label xml:lang="en">designated biospecimen</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000376 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000376">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000375"/>
        <obo:IAO_0000115 xml:lang="en">A &apos;designated biospecimen&apos; that designates a portion of excess tissue.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield, Kathleen Ford, Marcy Harris</obo:IAO_0000117>
        <obo:ICO_0000404 xml:lang="en"></obo:ICO_0000404>
        <rdfs:label xml:lang="en">designated residual tissue</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000377 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000377">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000326"/>
        <obo:IAO_0000115 xml:lang="en">A &apos;designated object&apos; that designates an unspecified object.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield, Kathleen Ford, Marcy Harris</obo:IAO_0000117>
        <obo:ICO_0000404 xml:lang="en"></obo:ICO_0000404>
        <rdfs:label xml:lang="en">designated unspecified object</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000378 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000378">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000325"/>
        <obo:IAO_0000115 xml:lang="en">A &apos;designated actor&apos; that designates an actor that may bear a permission role that may be realized in the process prescribed by the process designated by the &apos;designated action.&apos;</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield, Kathleen Ford, Marcy Harris</obo:IAO_0000117>
        <obo:ICO_0000404 xml:lang="en"></obo:ICO_0000404>
        <rdfs:comment xml:lang="en">(1) This designation points towards deontic roles and social processes.

(2) This can be read as: &apos;the actor TO BE permitted.&apos; It is not intended to create a permission the same way the creation of an ICO:permission role might. However, we leave this somewhat open to implementation interpretation.</rdfs:comment>
        <rdfs:label xml:lang="en">designated permitted actor</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000379 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000379">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000325"/>
        <obo:IAO_0000115 xml:lang="en">A &apos;designated actor&apos; that designates an actor with an affilitation to an organization or institution.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield, Kathleen Ford, Marcy Harris</obo:IAO_0000117>
        <obo:ICO_0000404 xml:lang="en"></obo:ICO_0000404>
        <rdfs:comment xml:lang="en">(1) actor with a designated affiliation to an organization/institution.

(2) intended for single individuals rather than groups, but as a way to relate groups and actors performing on the group&apos;s behalf.</rdfs:comment>
        <rdfs:label xml:lang="en">designated affiliated actor</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000380 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000380">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000325"/>
        <obo:IAO_0000115 xml:lang="en">A &apos;designated actor&apos; that designates a corporation.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield, Kathleen Ford, Marcy Harris</obo:IAO_0000117>
        <obo:ICO_0000404 xml:lang="en"></obo:ICO_0000404>
        <rdfs:label xml:lang="en">designated corporation</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000381 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000381">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000325"/>
        <obo:IAO_0000115 xml:lang="en">A &apos;designated actor&apos; that designates an institution.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield, Kathleen Ford, Marcy Harris</obo:IAO_0000117>
        <obo:ICO_0000404 xml:lang="en"></obo:ICO_0000404>
        <rdfs:comment xml:lang="en">(1) established organization

(2) an entity that has independent financial, legal, interests or identity.</rdfs:comment>
        <rdfs:label xml:lang="en">designated institution</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000382 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000382">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000325"/>
        <obo:IAO_0000115 xml:lang="en">A &apos;designated actor&apos; that designates a principal investigator.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield, Kathleen Ford, Marcy Harris</obo:IAO_0000117>
        <obo:ICO_0000404 xml:lang="en"></obo:ICO_0000404>
        <rdfs:label xml:lang="en">designated principal investigator</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000383 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000383">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000325"/>
        <obo:IAO_0000115 xml:lang="en">A &apos;designated actor&apos; that designates an information system.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield, Kathleen Ford, Marcy Harris</obo:IAO_0000117>
        <obo:ICO_0000404 xml:lang="en"></obo:ICO_0000404>
        <rdfs:label xml:lang="en">designated information system actor</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000384 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000384">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000325"/>
        <obo:IAO_0000115 xml:lang="en">A &apos;designated actor&apos; that designates an organization.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield, Kathleen Ford, Marcy Harris</obo:IAO_0000117>
        <obo:ICO_0000404 xml:lang="en"></obo:ICO_0000404>
        <rdfs:comment xml:lang="en">(1) where does surgical team fit in?

(2) how do we define aggregates of people?

(3) possible mapping to (OBI: organization) http://purl.obolibrary.org/obo/OBI_0000245</rdfs:comment>
        <rdfs:label xml:lang="en">designated organization</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000385 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000385">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000384"/>
        <obo:IAO_0000115 xml:lang="en">A &apos;designated organization&apos; that desginates an educational organization.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield, Kathleen Ford, Marcy Harris</obo:IAO_0000117>
        <obo:ICO_0000404 xml:lang="en"></obo:ICO_0000404>
        <rdfs:label xml:lang="en">designated educational organization</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000386 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000386">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000384"/>
        <obo:IAO_0000115 xml:lang="en">A &apos;designated organization&apos; that designates a biobank organization.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield, Kathleen Ford, Marcy Harris</obo:IAO_0000117>
        <obo:ICO_0000404 xml:lang="en"></obo:ICO_0000404>
        <rdfs:label xml:lang="en">designated biobank organization</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000387 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000387">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000384"/>
        <obo:IAO_0000115 xml:lang="en">A &apos;designated organization&apos; that designates a for-profit organization.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield, Kathleen Ford, Marcy Harris</obo:IAO_0000117>
        <obo:ICO_0000404 xml:lang="en"></obo:ICO_0000404>
        <rdfs:label xml:lang="en">designated for-profit organization</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000388 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000388">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000384"/>
        <obo:IAO_0000115 xml:lang="en">A &apos;designated organization&apos; that designates a funding organization.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield, Kathleen Ford, Marcy Harris</obo:IAO_0000117>
        <obo:ICO_0000404 xml:lang="en"></obo:ICO_0000404>
        <rdfs:label xml:lang="en">designated funding organization</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000389 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000389">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000384"/>
        <obo:IAO_0000115 xml:lang="en">A &apos;designated organization&apos; that designates a government organization.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield, Kathleen Ford, Marcy Harris</obo:IAO_0000117>
        <obo:ICO_0000404 xml:lang="en"></obo:ICO_0000404>
        <rdfs:label xml:lang="en">designated government organization</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000390 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000390">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000384"/>
        <obo:IAO_0000115 xml:lang="en">A &apos;designated organization&apos; that designates a healthcare organization.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield, Kathleen Ford, Marcy Harris</obo:IAO_0000117>
        <obo:ICO_0000404 xml:lang="en"></obo:ICO_0000404>
        <rdfs:label xml:lang="en">designated healthcare organization</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000391 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000391">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000384"/>
        <obo:IAO_0000115 xml:lang="en">A &apos;designated organization&apos; that designates a regulatory organization.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield, Kathleen Ford, Marcy Harris</obo:IAO_0000117>
        <obo:ICO_0000404 xml:lang="en"></obo:ICO_0000404>
        <rdfs:label xml:lang="en">designated regulatory organization</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000392 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000392">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000384"/>
        <obo:IAO_0000115 xml:lang="en">A &apos;designated organization&apos; that designates a media organization.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield, Kathleen Ford, Marcy Harris</obo:IAO_0000117>
        <obo:ICO_0000404 xml:lang="en"></obo:ICO_0000404>
        <rdfs:label xml:lang="en">designated media organization</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000393 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000393">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000384"/>
        <obo:IAO_0000115 xml:lang="en">A &apos;designated organization&apos; that designated a non-profit organization.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield, Kathleen Ford, Marcy Harris</obo:IAO_0000117>
        <obo:ICO_0000404 xml:lang="en"></obo:ICO_0000404>
        <rdfs:label xml:lang="en">designated non-profit organization</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000394 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000394">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000384"/>
        <obo:IAO_0000115 xml:lang="en">A &apos;designated organization&apos; that designates a public health organization.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield, Kathleen Ford, Marcy Harris</obo:IAO_0000117>
        <obo:ICO_0000404 xml:lang="en"></obo:ICO_0000404>
        <rdfs:comment xml:lang="en">(1) groups that may have the ability to override specific norms?</rdfs:comment>
        <rdfs:label xml:lang="en">designated public health organization</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000395 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000395">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000384"/>
        <obo:IAO_0000115 xml:lang="en">A &apos;designated organization&apos; that desginates a research organization.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield, Kathleen Ford, Marcy Harris</obo:IAO_0000117>
        <obo:ICO_0000404 xml:lang="en"></obo:ICO_0000404>
        <rdfs:label xml:lang="en">designated research organization</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000396 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000396">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000325"/>
        <obo:IAO_0000115 xml:lang="en">A &apos;designated actor&apos; that designates a team.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield, Kathleen Ford, Marcy Harris</obo:IAO_0000117>
        <obo:ICO_0000404 xml:lang="en"></obo:ICO_0000404>
        <rdfs:comment xml:lang="en">(1) this is useful in defining things like &apos;research team&apos; or &apos;clinical team.&apos;</rdfs:comment>
        <rdfs:label xml:lang="en">designated team</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000397 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000397">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000384"/>
        <obo:IAO_0000115 xml:lang="en">A &apos;designated organization&apos; that designates an unspecified organization.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield, Kathleen Ford, Marcy Harris</obo:IAO_0000117>
        <obo:ICO_0000404 xml:lang="en"></obo:ICO_0000404>
        <rdfs:label xml:lang="en">designated unspecified organization</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000398 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000398">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000325"/>
        <obo:IAO_0000115 xml:lang="en">A &apos;designated actor&apos; that designates an actor that may permit some &apos;designated action&apos;.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield, Kathleen Ford, Marcy Harris</obo:IAO_0000117>
        <obo:ICO_0000404 xml:lang="en"></obo:ICO_0000404>
        <rdfs:comment xml:lang="en">(1) This designation points towards deontic roles and social processes.</rdfs:comment>
        <rdfs:label xml:lang="en">designated permitting actor</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000399 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000399">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000325"/>
        <obo:IAO_0000115 xml:lang="en">A &apos;designated actor&apos; that designates the entity that is permitting some &apos;designated action&apos;.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield, Kathleen Ford, Marcy Harris</obo:IAO_0000117>
        <obo:ICO_0000404 xml:lang="en"></obo:ICO_0000404>
        <rdfs:comment xml:lang="en">(1) not to be confused with &apos;designated consenting actor&apos;.

(2) this definition is currently the same as the definition for &apos;designated consenting actor&apos;. We need to remedy this without appealing to U.S. specific legislative definitions.</rdfs:comment>
        <rdfs:label xml:lang="en">designated assenting actor</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000400 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000400">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000325"/>
        <obo:IAO_0000115 xml:lang="en">A &apos;designated actor&apos; that designates the actor that is permitting some &apos;designated action&apos;.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield, Kathleen Ford, Marcy Harris</obo:IAO_0000117>
        <obo:ICO_0000404 xml:lang="en"></obo:ICO_0000404>
        <rdfs:comment xml:lang="en">(1) Not to be confused with &apos;designed assenting actor&apos;

(2) By &apos;permitting&apos; we mean &apos;making the otherwise impermissable action permissable&apos; or &apos;making allowable.&apos;</rdfs:comment>
        <rdfs:label xml:lang="en">designated consenting actor</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000401 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000401">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000325"/>
        <obo:IAO_0000115 xml:lang="en">A &apos;designated actor&apos; that designates an authorized representative.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield, Kathleen Ford, Marcy Harris</obo:IAO_0000117>
        <obo:ICO_0000404 xml:lang="en"></obo:ICO_0000404>
        <rdfs:comment xml:lang="en">(1) legally authorized representative (LAR): has the ability to act on behalf of another person (under the rule of law).

(2) not sure if this should be under the &apos;designated permitting actor&apos;.

(3) surrogates are included here.</rdfs:comment>
        <rdfs:label xml:lang="en">designated authorized representative</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000403 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000403">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000325"/>
        <obo:IAO_0000115 xml:lang="en">A &apos;designated actor&apos; that designates an unspecified actor.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield, Kathleen Ford, Marcy Harris</obo:IAO_0000117>
        <obo:ICO_0000404 xml:lang="en"></obo:ICO_0000404>
        <rdfs:label xml:lang="en">designated unspecified actor</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000405 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000405">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000344"/>
        <obo:IAO_0000115 xml:lang="en">A &apos;designated research purpose&apos; that designates a health services research process as its end.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield, Kathleen Ford, Marcy Harris</obo:IAO_0000117>
        <rdfs:label xml:lang="en">designated health services research purpose</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000406 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000406">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000344"/>
        <obo:IAO_0000115 xml:lang="en">A &apos;designated research purpose&apos; that designates a process of methods development research as it&apos;s end.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield, Kathleen Ford, Marcy Harris</obo:IAO_0000117>
        <rdfs:label xml:lang="en">designated methods development purpose</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000407 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000407">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000344"/>
        <obo:IAO_0000115 xml:lang="en">A &apos;designated research purpose&apos; that designates reference control material research processes as its end.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield, Kathleen Ford, Marcy Harris</obo:IAO_0000117>
        <rdfs:label xml:lang="en">designated control material research purpose</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000408 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000408">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000344"/>
        <obo:IAO_0000115 xml:lang="en">A &apos;designated research purpose&apos; that designates a process of population research as its end.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield, Kathleen Ford, Marcy Harris</obo:IAO_0000117>
        <rdfs:label xml:lang="en">designated populations research purpose</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000409 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000409">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000344"/>
        <obo:IAO_0000115 xml:lang="en">A &apos;designated research purpose&apos; that designates ancestry research as its end.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield, Kathleen Ford, Marcy Harris</obo:IAO_0000117>
        <rdfs:label xml:lang="en">designated ancestry research purpose</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000410 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000410">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000345"/>
        <obo:IAO_0000115 xml:lang="en">A &apos;designated biomedical research purpose&apos; that designates a process of drug research as its end.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield, Kathleen Ford, Marcy Harris</obo:IAO_0000117>
        <rdfs:label xml:lang="en">designated drug research purpose</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000411 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000411">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000345"/>
        <obo:IAO_0000115 xml:lang="en">A &apos;designated biomedical research purpose&apos; that designates a process of disease specific research as its end.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield, Kathleen Ford, Marcy Harris</obo:IAO_0000117>
        <rdfs:label xml:lang="en">designated disease research purpose</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000412 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000412">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000345"/>
        <obo:IAO_0000115 xml:lang="en">A &apos;designated biomedical research purpose&apos; that designates a process of age category research as its end.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield, Kathleen Ford, Marcy Harris</obo:IAO_0000117>
        <rdfs:label xml:lang="en">designated age category research purpose</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000413 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000413">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000345"/>
        <obo:IAO_0000115 xml:lang="en">A &apos;designated biomedical research purpose&apos; that designates a process of gender category research as its end.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield, Kathleen Ford, Marcy Harris</obo:IAO_0000117>
        <rdfs:label xml:lang="en">designated gender research purpose</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000414 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000414">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000324"/>
        <obo:IAO_0000115 xml:lang="en">A &apos;designated action&apos; that designates a process of administration as permissable.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield, Kathleen Ford, Marcy Harris</obo:IAO_0000117>
        <obo:ICO_0000404 xml:lang="en"></obo:ICO_0000404>
        <rdfs:comment xml:lang="en">(1) This class is intended for actions such as &apos;drug administration.&apos;</rdfs:comment>
        <rdfs:label xml:lang="en">designated process of administration</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000415 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000415">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000326"/>
        <obo:IAO_0000115 xml:lang="en">A &apos;designated object&apos; that designates a pharmaceutical object</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield, Kathleen Ford, Marcy Harris</obo:IAO_0000117>
        <obo:ICO_0000404 xml:lang="en"></obo:ICO_0000404>
        <rdfs:label xml:lang="en">designated pharmaceutical object</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000416 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000416">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000328"/>
        <obo:IAO_0000115 xml:lang="en">A &apos;permission purpose directive&apos; that designates a process of recruitment.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield, Kathleen Ford, Marcy Harris</obo:IAO_0000117>
        <obo:ICO_0000404 xml:lang="en"></obo:ICO_0000404>
        <rdfs:label xml:lang="en">designated recruitment purpose</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000417 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000417">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000328"/>
        <obo:IAO_0000115 xml:lang="en">A &apos;permission purpose directive&apos; that designates a return of results.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield, Kathleen Ford, Marcy Harris</obo:IAO_0000117>
        <obo:ICO_0000404 xml:lang="en"></obo:ICO_0000404>
        <rdfs:comment xml:lang="en">(1) This is intended to cover communication from a healthcare organization to a patient or study participant regarding their health.</rdfs:comment>
        <rdfs:label xml:lang="en">designated return of results purpose</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000418 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000418">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000364"/>
        <obo:IAO_0000115 xml:lang="en">A &apos;permission requirement directive&apos; that directs sensitive infotmation proctection.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield, Kathleen Ford, Marcy Harris</obo:IAO_0000117>
        <obo:ICO_0000404 xml:lang="en"></obo:ICO_0000404>
        <rdfs:comment xml:lang="en">(1) This definition is left purposefully broad to cover a wide range of use cases including processes or methods.</rdfs:comment>
        <rdfs:label xml:lang="en">sensitive information protection directive</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000419 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000419">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000324"/>
        <obo:IAO_0000115 xml:lang="en">A &apos;designated action&apos; that designates a process fo treament.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield, Kathleen Ford, Marcy Harris</obo:IAO_0000117>
        <rdfs:comment xml:lang="en">(1) consent to treat</rdfs:comment>
        <rdfs:label xml:lang="en">designated process of treatment</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000421 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000421">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
        <obo:IAO_0000115 xml:lang="en">A planned process in which data is put to some use by an entity.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Cooper Stansbury, Elizabeth Umberfield</obo:IAO_0000117>
        <rdfs:label xml:lang="en">act of data use</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000422 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000422">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000053"/>
                        <owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/OBI_0000093"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <obo:IAO_0000115 xml:lang="en">An agent who bears a patient role.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">J. Neil Otte</obo:IAO_0000117>
        <rdfs:label xml:lang="en">patient</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000423 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000423">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/OBI_0000011"/>
        <obo:IAO_0000115 xml:lang="en">A planned process in which goods or services are exachanged for money.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Elizabeth Umberfield, Cooper Stansbury</obo:IAO_0000117>
        <obo:IAO_0000119 xml:lang="en">https://www.merriam-webster.com/dictionary/sell</obo:IAO_0000119>
        <obo:IAO_0000232 xml:lang="en">From definition of &apos;sell&apos; from Merriam-Webster: To give up (property) to another for something of value (such as money).&apos;</obo:IAO_0000232>
        <rdfs:label xml:lang="en">act of selling</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000424 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000424">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
        <obo:IAO_0000115 xml:lang="en">A role based on the Health Insurance Portability and Accountability Act that inheres in individuals, organizations, and agencies that are also health care providers, health plans, or health care clearinghouse.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Elizabeth Umberfield, Cooper Stansbury</obo:IAO_0000117>
        <obo:IAO_0000232 xml:lang="en">Adapted from HIPAA.</obo:IAO_0000232>
        <rdfs:label xml:lang="en">covered entity role</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000425 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000425">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000023"/>
        <obo:IAO_0000115 xml:lang="en">A role which is realized in processes of data disclosure.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Elizabeth Umberfield, Cooper Stansbury</obo:IAO_0000117>
        <obo:IAO_0000232 xml:lang="en">Definition from adapted from GDPR Article 4(9): A natural or legal person, public authority, agency or another body, to which the data are disclosed.</obo:IAO_0000232>
        <rdfs:label xml:lang="en">data recipient role</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000426 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000426">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ICO_0000103"/>
        <obo:IAO_0000115 xml:lang="en">Protected health information that excludes HIPAA-specified identifiers of the individual or of relatives, employers, or household members of the individual.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Elizabeth Umberfield, Cooper Stansbury</obo:IAO_0000117>
        <obo:IAO_0000232 xml:lang="en">Definition adapted from HIPAA.</obo:IAO_0000232>
        <rdfs:label xml:lang="en">limited data set</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000427 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000427">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/IAO_0000033"/>
        <obo:IAO_0000115 xml:lang="en">A directive information entity that prescribes the owner role.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Elizabeth Umberfield, Cooper Stansbury</obo:IAO_0000117>
        <rdfs:label xml:lang="en">owner role directive</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000428 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000428">
        <rdfs:subClassOf rdf:resource="http://www.ontologyrepository.com/CommonCoreOntologies/Stasis"/>
        <obo:IAO_0000115 xml:lang="en">A stasis in which an entity bears an ownership role.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Elizabeth Umberfield, Cooper Stansbury</obo:IAO_0000117>
        <rdfs:label xml:lang="en">ownership statis</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/ICO_0000429 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/ICO_0000429">
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
        <obo:IAO_0000115 xml:lang="en">A material entity, collected during some health care process, that bears both a specimen role and an excess material role following some act of artifact modification.</obo:IAO_0000115>
        <obo:IAO_0000117 xml:lang="en">Elizabeth Umberfield, Cooper Stansbury</obo:IAO_0000117>
        <rdfs:label xml:lang="en">residual clinical biospecimen</rdfs:label>
    </owl:Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_9606 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
    


    <!-- http://purl.obolibrary.org/obo/OBI_0000011 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000011"/>
    


    <!-- http://purl.obolibrary.org/obo/OBI_0000066 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000066"/>
    


    <!-- http://purl.obolibrary.org/obo/OBI_0000093 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000093"/>
    


    <!-- http://purl.obolibrary.org/obo/OBI_0000181 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000181"/>
    


    <!-- http://purl.obolibrary.org/obo/OBI_0000245 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000245"/>
    


    <!-- http://purl.obolibrary.org/obo/OBI_0000272 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000272"/>
    


    <!-- http://purl.obolibrary.org/obo/OBI_0000810 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000810"/>
    


    <!-- http://purl.obolibrary.org/obo/OBI_0001000 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001000"/>
    


    <!-- http://purl.obolibrary.org/obo/OBI_0001622 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001622"/>
    


    <!-- http://purl.obolibrary.org/obo/OBI_0100051 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0100051"/>
    


    <!-- http://purl.obolibrary.org/obo/OGMS_0000090 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000090"/>
    


    <!-- http://purl.obolibrary.org/obo/OGMS_0000102 -->

    <owl:Class rdf:about="http://purl.obolibrary.org/obo/OGMS_0000102"/>
    


    <!-- http://purl.unep.org/sdg/SDGIO_00000024 -->

    <owl:Class rdf:about="http://purl.unep.org/sdg/SDGIO_00000024"/>
    


    <!-- http://www.geneontology.org/formats/oboInOwl#ObsoleteClass -->

    <owl:Class rdf:about="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
    


    <!-- http://www.ontologyrepository.com/CommonCoreOntologies/DescriptiveInformationContentEntity -->

    <owl:Class rdf:about="http://www.ontologyrepository.com/CommonCoreOntologies/DescriptiveInformationContentEntity"/>
    


    <!-- http://www.ontologyrepository.com/CommonCoreOntologies/DesignativeInformationContentEntity -->

    <owl:Class rdf:about="http://www.ontologyrepository.com/CommonCoreOntologies/DesignativeInformationContentEntity"/>
    


    <!-- http://www.ontologyrepository.com/CommonCoreOntologies/Stasis -->

    <owl:Class rdf:about="http://www.ontologyrepository.com/CommonCoreOntologies/Stasis"/>
    


    <!-- http://www.ontologyrepository.com/CommonCoreOntologies/StasisOfGenericallyDependentContinuant -->

    <owl:Class rdf:about="http://www.ontologyrepository.com/CommonCoreOntologies/StasisOfGenericallyDependentContinuant"/>
</rdf:RDF>



<!-- Generated by the OWL API (version 4.5.29) https://github.com/owlcs/owlapi -->