No. This repo is an agent-ready workflow layer: manifests, schemas, validators, skills, issue contracts, map/model review demos, figure workflows, and provider run checks. Real processing uses operator-owned runtimes and storage outside git.
Those are processing or workflow systems. CryoCore helps agents plan and review the work around them: declared inputs, map/model questions, figure outputs, state comparisons, provider runs, provenance, artifact checks, and claim boundaries. It can describe lanes that use tools such as RELION or CryoSPARC, but it does not redistribute or bypass those tools.
Yes. The main release checks and no-download fixtures are local. Some examples query public accession APIs when explicitly run.
The validators, release checks, public snapshot scans, docs link checks, skill checks, schemas, and the tiny T2R14 public-coordinate demo. Start with Public Quickstart.
Nothing in the default release gate. Paid provider execution, GPU runs, raw data transfer, and large storage are operator-owned activities outside this public repo. See Provider Execution Model.
No public default does that. Raw movie lanes are gated and must run outside git with explicit operator authorization, scratch storage, and fetched-artifact review.
Cryo-EM workflows often need tools with noncommercial, academic, binary, or redistribution constraints. Public docs can model those gates; public images and default commands must not bypass them.
Yes. Use Adoption Guide. Keep private data, local paths, credentials, license files, and provider logs out of any public skill bundle or issue text.
Use CITATION.cff for the software repo, and also cite the specific public accessions, tools, and datasets used by your run. CryoCore is not a substitute for primary scientific citations.
Start with the skills, schemas, claim-level docs, provider run checks, and public snapshot checks. Keep project-specific accessions, licenses, and private data out of reusable templates.
No. The demos and validators are engineering support for evidence workflows. They do not establish clinical, therapeutic, regulatory, or final biological mechanism claims.